CAJ | 학술논문

目的评价点阵二氧化碳激光联合液氮冷冻治疗扁平疣的临床疗效和安全性.方法将83例扁平疣患者按治疗方法分为两组,观察组42例予点阵二氧化碳激光联合液氮冷冻治疗,对照组41例予液氮冷冻治疗,均10d为1个疗程,共治疗2个疗程.比较两组疗效、复发情况及不良反应.结果观察组第1和2个疗程后痊愈率明显高于对照组[73.81％(31/42)比46.34％(19/41)和97.62％(41/42)比75.61％(31/41)],观察组复发率和不良反应发生率明显低于对照组[2.44％(1/41)比19.35％(6/31)和9.52％(4/42)比31.71％(13/41)],差异均有统计学意义(P＜ 0.05或＜ 0.01).结论点阵二氧化碳激光联合液氮冷冻治疗扁平疣可明显提高痊愈率,降低复发率,而且安全.
목적 평개점진이양화탄격광연합액담냉동치료편평우적림상료효화안전성.방법 장83례편평우환자안치료방법분위량조,관찰조42례여점진이양화탄격광연합액담냉동치료,대조조41례여액담냉동치료,균10d위1개료정,공치료2개료정.비교량조료효、복발정황급불량반응.결과 관찰조제1화2개료정후전유솔명현고우대조조[73.81％(31/42)비46.34％(19/41)화97.62％(41/42)비75.61％(31/41)],관찰조복발솔화불량반응발생솔명현저우대조조[2.44％(1/41)비19.35％(6/31)화9.52％(4/42)비31.71％(13/41)],차이균유통계학의의(P＜ 0.05혹＜ 0.01).결론 점진이양화탄격광연합액담냉동치료편평우가명현제고전유솔,강저복발솔,이차안전.
Objective To evaluate the clinical efficacy and safety about carbon dioxide fractional laser combined with liquid nitrogen cryotherapy for flat warts.Methods Eighty-three patients with flat warts were divided into 2 groups according to the treatment method,42 patients in treatment group were treated by carbon dioxide fractional laser combined with liquid nitrogen cryotherapy,41 patients in control group were treated by liquid nitrogen cryotherapy alone.As a period for 10 days,2 groups were given 2 periods of treatment.The therapeutic effect,recurrence rate and adverse reaction were compared between 2 groups.Results The cure rates of 1-period and 2-period in treatment group were significantly higher than those in control group [73.81％(31/42) vs.46.34％(19/41) and 97.62％(41/42) vs.75.61％(31/41)],the recurrence rate and incidence of adverse reaction in treatment group were significantly lower than those in control group [2.44％(1/41) vs.19.35％(6/31) and 9.52％(4/42) vs.31.71％(13/41)],there were statistical differences (P ＜ 0.05 or ＜ 0.01).Conclusion Carbon dioxide fractional laser combined with liquid nitrogen cryotherapy for fiat warts is a safe and effective treatment with low recurrence rate.