中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2014年
28期
23-26
,共4页
李龙钦%崔伯塔%戴译萱%彭炤源%王敏%季国忠%张发明
李龍欽%崔伯塔%戴譯萱%彭炤源%王敏%季國忠%張髮明
리룡흠%최백탑%대역훤%팽소원%왕민%계국충%장발명
炎症性肠病%结肠炎,溃疡性%克罗恩病%诊断%治疗
炎癥性腸病%結腸炎,潰瘍性%剋囉恩病%診斷%治療
염증성장병%결장염,궤양성%극라은병%진단%치료
Inflammatory bowel disease%Colitis,ulcerative%Crohn's disease%Diagnosis%Treatment
目的 探讨炎症性肠病(IBD)患者的临床治疗现状.方法 调查122例IBD患者的临床特点及诊疗特征.结果 122例IBD患者中,54例为溃疡性结肠炎(UC),病变范围以广泛结肠为主,就诊医院中位数3家,使用氨基水杨酸制剂、糖皮质激素、免疫抑制剂、生物制剂和抗生素分别为100.0％(54/54),55.6％(30/54),24.1％(13/54),7.4％ (4/54),75.9％(41/54);68例为克罗恩病(CD),病变范围以空回肠+结肠为主,就诊医院中位数4家,使用过氨基水杨酸制剂、糖皮质激素、免疫抑制剂、生物制剂和抗生素分别为95.6％(65/68),58.8％(40/68),47.1％(32/68),11.8％ (8/68),79.4％(54/68).CD患者使用免疫抑制剂、喹诺酮类抗生素均高于UC患者,使用中草药治疗的低于UC患者,差异有统计学意义(P＜0.05).结论 目前治疗IBD的主要药物有氨基水杨酸制剂、糖皮质激素、免疫抑制剂、生物制剂.
目的 探討炎癥性腸病(IBD)患者的臨床治療現狀.方法 調查122例IBD患者的臨床特點及診療特徵.結果 122例IBD患者中,54例為潰瘍性結腸炎(UC),病變範圍以廣汎結腸為主,就診醫院中位數3傢,使用氨基水楊痠製劑、糖皮質激素、免疫抑製劑、生物製劑和抗生素分彆為100.0％(54/54),55.6％(30/54),24.1％(13/54),7.4％ (4/54),75.9％(41/54);68例為剋囉恩病(CD),病變範圍以空迴腸+結腸為主,就診醫院中位數4傢,使用過氨基水楊痠製劑、糖皮質激素、免疫抑製劑、生物製劑和抗生素分彆為95.6％(65/68),58.8％(40/68),47.1％(32/68),11.8％ (8/68),79.4％(54/68).CD患者使用免疫抑製劑、喹諾酮類抗生素均高于UC患者,使用中草藥治療的低于UC患者,差異有統計學意義(P＜0.05).結論 目前治療IBD的主要藥物有氨基水楊痠製劑、糖皮質激素、免疫抑製劑、生物製劑.
목적 탐토염증성장병(IBD)환자적림상치료현상.방법 조사122례IBD환자적림상특점급진료특정.결과 122례IBD환자중,54례위궤양성결장염(UC),병변범위이엄범결장위주,취진의원중위수3가,사용안기수양산제제、당피질격소、면역억제제、생물제제화항생소분별위100.0％(54/54),55.6％(30/54),24.1％(13/54),7.4％ (4/54),75.9％(41/54);68례위극라은병(CD),병변범위이공회장+결장위주,취진의원중위수4가,사용과안기수양산제제、당피질격소、면역억제제、생물제제화항생소분별위95.6％(65/68),58.8％(40/68),47.1％(32/68),11.8％ (8/68),79.4％(54/68).CD환자사용면역억제제、규낙동류항생소균고우UC환자,사용중초약치료적저우UC환자,차이유통계학의의(P＜0.05).결론 목전치료IBD적주요약물유안기수양산제제、당피질격소、면역억제제、생물제제.
Objective To investigate the clinical situation of inflammatory bowel disease (IBD).Methods The clinical features and treatment features of 122 patients with IBD were investigated.Results In 122 IBD patients,54 cases had ulcerative colitis (UC),the lesion was in colon,hospital number visited was median 3,the ratios of using amino salicylic acid salts,hormones,immunosuppressive agents,biological agents and antibiotics was 100.0％ (54/54),55.6％ (30/54),24.1％ (13/54),7.4％ (4/54) and 75.9％ (41/54); 68 cases had Crohn disease (CD),the lesion was in the ileocolic,hospital number visited was median 4,the ratios of using amino salicylic acid salts,hormones,immunosuppressive agents,biological agents and antibiotics was 95.6％ (65/68),58.8％ (40/68),47.1％ (32/68),11.8％ (8/68) and 79.4％ (54/68).The uses of CD in patients with immunosuppression,quinolone antibiotics in patients of CD were higher than those of patients with UC,the use of herbal medicine in patients of CD was lower than that in patients of UC,the difference was statistically significant (P ＜ 0.05).Conclusion The main drugs currently used to treat IBD are amino salicylic acid preparation,corticosteroids,immunosuppressive agents,biological agents.
