CAJ | 학술논문

目的探讨羊膜移植治疗反复性角膜上皮糜烂的临床疗效.方法回顾性分析保存生物羊膜移植治疗的20例(21眼)反复性角膜上皮糜烂住院患者,术后随访观察3～16个月,对术后角膜上皮完全修复时间、视力提高情况进行分析评价.结果 21眼中19眼单纯羊膜移植术,术后角膜上皮完全修复时间最短3d,最长28 d;1眼于术后第8天羊膜融解,角膜上皮未愈合,经再次手术并联合佩戴角膜接触镜治疗后角膜上皮完全修复;1眼首次手术及联合佩戴角膜接触镜治疗,术后7d角膜上皮完全修复.术后视力提高(t=2.613,P=0.02).结论羊膜移植是治疗反复性角膜上皮糜烂的有效方法.
목적 탐토양막이식치료반복성각막상피미란적림상료효.방법 회고성분석보존생물양막이식치료적20례(21안)반복성각막상피미란주원환자,술후수방관찰3～16개월,대술후각막상피완전수복시간、시력제고정황진행분석평개.결과 21안중19안단순양막이식술,술후각막상피완전수복시간최단3d,최장28 d;1안우술후제8천양막융해,각막상피미유합,경재차수술병연합패대각막접촉경치료후각막상피완전수복;1안수차수술급연합패대각막접촉경치료,술후7d각막상피완전수복.술후시력제고(t=2.613,P=0.02).결론 양막이식시치료반복성각막상피미란적유효방법.
Objective To study the clinical efficacy of amniotic membrane transplantation for recurrent corneal epithelial erosion.Methods We retrospectively analyzed 21 eyes of 20 cases with recurrent corneal epithelial erosion treated by amniotic membrane transplantation.The follow-up time was 3-16months.The complete repair time of corneal epithelium and the improvement of visual acuity were evaluated.Results Of the 21 eyes,19 eyes underwent amniotic membrane transplantation and the shortest repair time of corneal epithelium was 3 days,the longest was 28 days.The amniotic membrane of 1 eye was dissolved at 8 d after operation,and the comeal epithelium did not repair until reoperation of transplantation combined with wearing corneal contact lens.The comeal epithelium of the other 1 eye completely repaired at 7 d after amniotic membrane transplantation combined with wearing corneal contact lens.The visual acuity was improved after surgery (t =2.613,P =0.02).Conclusion Amniotic membrane transplantation is effective for the treatment of recurrent corneal epithelial erosion.