CAJ | 학술논문

目的了解轻度碘缺乏沿海地区连云港市2002-2010年甲状腺肿大(甲肿)患者住院率的变化.方法采用回顾性调查方法,在连云港市县级以上医院,调查甲肿患者的住院情况.按照《全国碘盐监测方案》,每个县(区)[共计5个县(区)]抽取9个乡(镇),每个乡(镇)抽取4个村,每个村抽取8户居民户盐样,采用硫代硫酸钠直接滴定法检测盐碘.结果甲肿住院率从2002年的1.87/10万上升为2009年的7.05/10万,再波动为2010年的6.06/10万(x2=281.91,P均＜0.01).从2002到2010年,女性甲肿住院率显著性高于男性(x2值范围为35.23～116.04,P均＜0.01),≥40岁人群甲肿住院率高于＜40岁人群(x2值范围为33.04 ～263.04,P均＜0.01),城市甲肿住院率高于农村(x2值范围为18.35～140.00,P均＜0.01).2002-2010年居民盐碘均值范围为27.61～30.13mg/kg.居民盐碘覆盖率、合格碘盐食用率逐年增加(x2=183.75、211.99,P均＜0.01),且与甲肿住院率均存在正相关关系(spearman相关系数分别为0.83、0.93,P均＜0.05).结论 2002-2010年连云港市甲肿住院率、居民盐碘覆盖率、合格碘盐食用率均呈现上升趋势,它们之间的关系值得深入研究.
목적 료해경도전결핍연해지구련운항시2002-2010년갑상선종대(갑종)환자주원솔적변화.방법 채용회고성조사방법,재련운항시현급이상의원,조사갑종환자적주원정황.안조《전국전염감측방안》,매개현(구)[공계5개현(구)]추취9개향(진),매개향(진)추취4개촌,매개촌추취8호거민호염양,채용류대류산납직접적정법검측염전.결과 갑종주원솔종2002년적1.87/10만상승위2009년적7.05/10만,재파동위2010년적6.06/10만(x2=281.91,P균＜0.01).종2002도2010년,녀성갑종주원솔현저성고우남성(x2치범위위35.23～116.04,P균＜0.01),≥40세인군갑종주원솔고우＜40세인군(x2치범위위33.04 ～263.04,P균＜0.01),성시갑종주원솔고우농촌(x2치범위위18.35～140.00,P균＜0.01).2002-2010년거민염전균치범위위27.61～30.13mg/kg.거민염전복개솔、합격전염식용솔축년증가(x2=183.75、211.99,P균＜0.01),차여갑종주원솔균존재정상관관계(spearman상관계수분별위0.83、0.93,P균＜0.05).결론 2002-2010년련운항시갑종주원솔、거민염전복개솔、합격전염식용솔균정현상승추세,타문지간적관계치득심입연구.
Objective To observe the changes of hospitalization rates of patients with goiter in Lianyungang City in a coastal area with mild iodine deficiency in 2002-2010.Methods Medical reports of patients with goiter from county hospitals were studied at county level with a retrospective method.In accordance with the "National Iodized Salt Monitoring Program",nine townships(towns) were taken from each county (district) [total of five counties(districts)]; four villages were selected from each township (town); salt samples were taken from eight households in each village,and salt iodine was determined using direct titration of sodium thiosulfate.Results The hospitalization rate of patient with goiter increased from 1.87/10 million in 2002 to 7.05/10 million in 2009,and then fluctuated to 6.06/10 million in 2010(x2 =281.91,P＜ 0.01).Among them,female's hospitalization rates were significantly higher than that of male 's(The variation range of x2 values were 35.23-116.04,all P ＜ 0.01),and the hospitalization rates of people over the age of 40 years were significantly higher than that of people less than 40 years of age(The variation range of x2 values were 33.04-263.04,all P ＜ 0.01),and the hospitalization rates of people in urban areas were significantly higher than that of people in rural areas (The variation range of x2 values were 18.35-140.00,all P ＜ 0.01).Average salt iodine was 27.61-30.13 mg/kg in 2002-2010.The coverage rate of iodized salt and the consumption rate of qualified iodized salt both increased year by year (x2 =183.75,211.99,P ＜ 0.01).There was a positive correlation between hospitalization rate of patient with goiter and coverage rate of iodized salt(spearman correlation coefficient was 0.83,P ＜ 0.05).There was a positive correlation between hospitalization rate of patient with goiter and the consumption rate of qualified iodized salt too (spearman correlation coefficient was 0.93,P ＜ 0.05).Conclusions In Lianyungang City,the hospitalization rate of patient with goiter,the coverage rate of iodized salt and the consumption rate of qualified iodized salt all show upward trend in 2002-2010.The relationship among them is worth further study.