CAJ | 학술논문

目的探讨免疫功能正常的马尔尼菲青霉病的临床特点.方法分析总结4例免疫功能正常的马尔尼菲青霉病患者的临床资料.结果患者临床表现主要有间歇性低-中热、淋巴结肿大、皮损、溶骨性破坏、贫血及白细胞升高.血液、脓液等标本培养马尔尼菲青霉菌阳性率较高.两性霉素B、伊曲康唑治疗效果较好.结论马尔尼菲青霉菌可感染免疫功能正常的人群,临床表现无特异性,及时、有效的抗真菌治疗可改善患者的预后.
목적 탐토면역공능정상적마이니비청매병적림상특점.방법 분석총결4례면역공능정상적마이니비청매병환자적림상자료.결과 환자림상표현주요유간헐성저-중열、림파결종대、피손、용골성파배、빈혈급백세포승고.혈액、농액등표본배양마이니비청매균양성솔교고.량성매소B、이곡강서치료효과교호.결론 마이니비청매균가감염면역공능정상적인군,림상표현무특이성,급시、유효적항진균치료가개선환자적예후.
Objective To discuss the clinical features of immunocompetent patients with Penicilliosis marneffei.Methods To analyze and summarize the clinical data of 4 immunocompetent patients with Penicilliosis marneffei.Results Clinical manifestation of patients centered on intermittent slight or mild fever,lymphadenectasis,skin eruptions,osteolytic destruction,anaemia,and leukocytosis.The cultural Penicillium marneffei in specimen such as blood,pus showed a higher positive rate.Amphotericin B and itraconazole was available in treatment.Conclusion Immunocompetent people can be infected by Penicillium marneffei,and they appear nonspecific in clinical manifestation after infection.A timely and effective antifungal therapy can improve the prognosis of patients.