CAJ | 학술논문

目的探讨中药消风止痒颗粒联合左西替利嗪治疗老年荨麻疹患者的疗效以及对老年患者血清白细胞介素2(IL-2)与IgE的影响.方法 96例老年荨麻疹患者随机分成治疗组和对照组,治疗组用消风止痒颗粒联合左西替利嗪,对照组用左西替利嗪,2周为1个疗程.观察两组的治疗效果,以及两组患者血清IL-2与IgE水平.结果治疗组和对照组治愈率分别为69.6％和52.5％,两组差异有统计学意义(P＜0.05).治疗组血清IL-2与IgE均较对照组明显下降(均P＜0.01).结论消风止痒颗粒联合左西替利嗪治疗老年荨麻疹患者效果较好,能显著降低患者血清IL-2与IgE水平.
목적 탐토중약소풍지양과립연합좌서체리진치료노년담마진환자적료효이급대노년환자혈청백세포개소2(IL-2)여IgE적영향.방법 96례노년담마진환자수궤분성치료조화대조조,치료조용소풍지양과립연합좌서체리진,대조조용좌서체리진,2주위1개료정.관찰량조적치료효과,이급량조환자혈청IL-2여IgE수평.결과 치료조화대조조치유솔분별위69.6％화52.5％,량조차이유통계학의의(P＜0.05).치료조혈청IL-2여IgE균교대조조명현하강(균P＜0.01).결론 소풍지양과립연합좌서체리진치료노년담마진환자효과교호,능현저강저환자혈청IL-2여IgE수평.
Objective To study the effects of Xiaofengzhiyang Particles and Levocetirizine on elderly urticaria and effects on the serum levels of IL-2 and IgE.Methods 96 elderly patients were randomly divided into two groups.The patients in study group were prescribed with Xiaofengzhiyang Particles and Levocetirizine.The patients in control group were prescribed with Levocetirizine,two weeks for a course.The curative effect and serum levels of IL-2 and IgE were observed after treatment.Results The complete cure rate of the study group was 69.6％,the control group was 52.5％.There was significant difference between the two groups(P＜0.05).The serum levels of IL-2 and IgE were significantly decreased in study group(all P＜0.01).Conclusion Xiaofengzhiyang Particles combined with Levocetirizine is effective in treating elderly urticaria,and the two drugs together could reduce the serum levels of IL-2 and IgE.