CAJ | 학술논문

目的观察参麦注射液对局部晚期非小细胞肺癌同步放化疗患者免疫功能的影响.方法将80例局部晚期非小细胞肺癌患者随机均分为治疗组和对照组.对照组给予三维适形放疗同步TP(多西他赛+顺铂)方案化疗.治疗组在对照组基础上同时给予参麦注射液治疗.观察两组T细胞亚群变化.结果两组治疗前CD+3、CD+4、CD+8、CD+4/CD+8和CD+16 CD+56差异均无统计学意义(均P＞0.05).治疗组应用参麦注射液后未出现明显不良反应.结论参麦注射液联合同步放化疗治疗局部晚期非小细胞肺癌,对提高机体免疫力具有重要作用.
목적 관찰삼맥주사액대국부만기비소세포폐암동보방화료환자면역공능적영향.방법 장80례국부만기비소세포폐암환자수궤균분위치료조화대조조.대조조급여삼유괄형방료동보TP(다서타새+순박)방안화료.치료조재대조조기출상동시급여삼맥주사액치료.관찰량조T세포아군변화.결과 량조치료전CD+3、CD+4、CD+8、CD+4/CD+8화CD+16 CD+56차이균무통계학의의(균P＞0.05).치료조응용삼맥주사액후미출현명현불량반응.결론 삼맥주사액연합동보방화료치료국부만기비소세포폐암,대제고궤체면역력구유중요작용.
Objective To observe the effect of Shenmai injection combined concurrent chemoradiotherapy on immune function in patients with locally advanced non-small cell lung cancer.Methods A total of 80 patients with locally advanced non-small cell lung cancer were randomly divided into treatment group and control group.In treatment group,40 patients received simultaneous three-dimensional conformal radiotherapy combined with TP(docetaxel+cisplatin)chemotherapy,while given Shenmai injection in the process of concurrent chemoradiotherapy.In control group,40 patients only received chemoradiotherapy.The changes of T cell subsets were observed between the two groups.Results It showed no significant differences in percentages of CD+3,CD+4,CD+16CD+56and CD+4/CD+8 ratio between two groups pre-treatment(all P＞0.05).There were no significant adverse reactions occurred after received Shenmai injection in treatment group.Conclusion It play an important role in improving immune function of patients with locally advanced non-small cell lung cancer who received Shenmai injection combined concurrent chemoradiotherapy.