中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
8期
1162-1163
,共2页
肺炎,支原体%阿奇霉素%糖皮质激素%儿童
肺炎,支原體%阿奇黴素%糖皮質激素%兒童
폐염,지원체%아기매소%당피질격소%인동
Pneumonia,mycoplasma%Azithromycin%Glucocorticoid%Children
目的 研究阿奇霉素联合糖皮质激素治疗小儿支原体肺炎的临床疗效.方法 选择支原体肺炎患儿124例,随机分为研究组和对照组,每组62例.在进行常规对症治疗的基础上,对照组给予阿奇霉素,剂量为10 mg·kg-1·d-1.研究组在治疗前5d合用阿奇霉素与氢化可的松琥珀酸钠(剂量为0.2 mg/kg),5d后停用氢化可的松琥珀酸钠,总疗程为2周.结果 研究组患儿咳嗽、发热和肺部啰音消失时间明显短于对照组.研究组有效率为95.2％,对照组为83.9％,差异有统计学意义(P＜0.05).研究组有9例患儿出现不良反应,对照组为14例,差异有统计学意义(P＜0.05).结论 糖皮质激素联合阿奇霉素治疗小儿肺炎支原体肺炎,可提高治疗疗效,缩短治疗时间,是小儿肺炎支原体肺炎临床治疗的较好选择.
目的 研究阿奇黴素聯閤糖皮質激素治療小兒支原體肺炎的臨床療效.方法 選擇支原體肺炎患兒124例,隨機分為研究組和對照組,每組62例.在進行常規對癥治療的基礎上,對照組給予阿奇黴素,劑量為10 mg·kg-1·d-1.研究組在治療前5d閤用阿奇黴素與氫化可的鬆琥珀痠鈉(劑量為0.2 mg/kg),5d後停用氫化可的鬆琥珀痠鈉,總療程為2週.結果 研究組患兒咳嗽、髮熱和肺部啰音消失時間明顯短于對照組.研究組有效率為95.2％,對照組為83.9％,差異有統計學意義(P＜0.05).研究組有9例患兒齣現不良反應,對照組為14例,差異有統計學意義(P＜0.05).結論 糖皮質激素聯閤阿奇黴素治療小兒肺炎支原體肺炎,可提高治療療效,縮短治療時間,是小兒肺炎支原體肺炎臨床治療的較好選擇.
목적 연구아기매소연합당피질격소치료소인지원체폐염적림상료효.방법 선택지원체폐염환인124례,수궤분위연구조화대조조,매조62례.재진행상규대증치료적기출상,대조조급여아기매소,제량위10 mg·kg-1·d-1.연구조재치료전5d합용아기매소여경화가적송호박산납(제량위0.2 mg/kg),5d후정용경화가적송호박산납,총료정위2주.결과 연구조환인해수、발열화폐부라음소실시간명현단우대조조.연구조유효솔위95.2％,대조조위83.9％,차이유통계학의의(P＜0.05).연구조유9례환인출현불량반응,대조조위14례,차이유통계학의의(P＜0.05).결론 당피질격소연합아기매소치료소인폐염지원체폐염,가제고치료료효,축단치료시간,시소인폐염지원체폐염림상치료적교호선택.
Objective To investigate the clinical effects of azithromycin combined with glucocorticoid for the mycoplasma pneumonia in children.Methods 124 children with mycoplasma pneumonia were randomly divided into the study group and the control group with 62 cases in each group.On the basis of the routine symptomatic treatment,the control group was given azithromycin(10mg · kg-1 · d-1) and the study group was treated with azithromycin and hydrocortisone sodium succinate (0.2mg/kg) in the first five days,then stop giving hydrocortisone sodium succinate.The total course was two weeks.Results The study group of children with cough,fever and pulmonary rales disappeared significantly shorter than the control group.Comparison of clinical efficacy,the study group effective rate was 95.2％,the control group was 83.9％,the difference was statistically significant (P ＜ 0.05).Study group had 9 cases of adverse reactions,the control group had 14 cases of adverse reactions,the difference was statistically significant (P ＜ 0.05).Conclusion Glucocorticoid combined with azithromycin is used to treat children with mycoplasma pneumoniae pneumonia,which can improve the therapeutic efficacy and shorten treatment time.It is a better choice of clinical treatment for mycoplasma pneumoniae pneumonia in children.
