中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
11期
1608-1610
,共3页
代谢综合征%抵抗素%胰岛素
代謝綜閤徵%牴抗素%胰島素
대사종합정%저항소%이도소
Metabolic syndrome%Resistin%Insulin
目的 探讨蒙古族、汉族代谢综合征患者抵抗素水平差异及相关因素分析.方法 根据代谢综合征的诊断标准,从健康体检人群中随机抽样选取蒙古族、汉族代谢综合征患者58例,其中蒙古族代谢综合征30例(1组),汉族代谢综合征28例(2组).采用放射免疫方法检测血清抵抗素,同时检测身高、体质量、血压、血糖、血脂、血尿酸、瘦素、胰岛素,并计算体质量指数和胰岛素抵抗指数并比较.结果 两组收缩压、瘦素、抵抗素、胰岛素和胰岛素抵抗指数差异均有统计学意义(均P ＜0.05).两组年龄、舒张压、体质量指数、高密度脂蛋白、低密度脂蛋白、甘油三酯、总胆固醇、血尿酸和空腹血糖差异均无统计学意义(均P＞0.05).1组抵抗素水平的升高与血尿酸、收缩压和胰岛素抵抗指数相关(r=0.357、0.427、0.582,均P＜0.05).结论 蒙古族代谢综合征患者抵抗素水平与血尿酸、收缩压和胰岛素抵抗指数相关,抵抗素在代谢综合征的形成与发展中起重要作用.
目的 探討矇古族、漢族代謝綜閤徵患者牴抗素水平差異及相關因素分析.方法 根據代謝綜閤徵的診斷標準,從健康體檢人群中隨機抽樣選取矇古族、漢族代謝綜閤徵患者58例,其中矇古族代謝綜閤徵30例(1組),漢族代謝綜閤徵28例(2組).採用放射免疫方法檢測血清牴抗素,同時檢測身高、體質量、血壓、血糖、血脂、血尿痠、瘦素、胰島素,併計算體質量指數和胰島素牴抗指數併比較.結果 兩組收縮壓、瘦素、牴抗素、胰島素和胰島素牴抗指數差異均有統計學意義(均P ＜0.05).兩組年齡、舒張壓、體質量指數、高密度脂蛋白、低密度脂蛋白、甘油三酯、總膽固醇、血尿痠和空腹血糖差異均無統計學意義(均P＞0.05).1組牴抗素水平的升高與血尿痠、收縮壓和胰島素牴抗指數相關(r=0.357、0.427、0.582,均P＜0.05).結論 矇古族代謝綜閤徵患者牴抗素水平與血尿痠、收縮壓和胰島素牴抗指數相關,牴抗素在代謝綜閤徵的形成與髮展中起重要作用.
목적 탐토몽고족、한족대사종합정환자저항소수평차이급상관인소분석.방법 근거대사종합정적진단표준,종건강체검인군중수궤추양선취몽고족、한족대사종합정환자58례,기중몽고족대사종합정30례(1조),한족대사종합정28례(2조).채용방사면역방법검측혈청저항소,동시검측신고、체질량、혈압、혈당、혈지、혈뇨산、수소、이도소,병계산체질량지수화이도소저항지수병비교.결과 량조수축압、수소、저항소、이도소화이도소저항지수차이균유통계학의의(균P ＜0.05).량조년령、서장압、체질량지수、고밀도지단백、저밀도지단백、감유삼지、총담고순、혈뇨산화공복혈당차이균무통계학의의(균P＞0.05).1조저항소수평적승고여혈뇨산、수축압화이도소저항지수상관(r=0.357、0.427、0.582,균P＜0.05).결론 몽고족대사종합정환자저항소수평여혈뇨산、수축압화이도소저항지수상관,저항소재대사종합정적형성여발전중기중요작용.
Objective To explore the differences of resistin level between Mongol and Han population in patients with metabolic syndrome and to analyze its related factors.Methods According to the diagnostic criterion of metabolic syndrome,30 patients with metabolic syndrome in Mongol population (group 1) and 28 patients with metabolic syndrome in Han population(group 2) were randomly selected from health examination population.Radioimmunoassay kit was used to examine the serum resistin level in patients with metabolic syndrome.At the same time,their weight,height,blood pressure,blood glucose,blood lipid [high density lipoprotein (HDL),low density lipoprotein (LDL),total cholesterol (TC),glycerin three greases (TG)],blood uric acid (UA),leptin,insulin were measured,and body mass index(BMI) and insulin resistance index(HOMA-IR) were counted and compared.Results There were significant differences in systolic pressure,leptin,resistin,blood insulin and HOMA-IR between the two groups(all P ＜ 0.05).There were no significant differences in age,diastolic pressure,BMI,HDL,LDL,TG,TC,UA and blood glucose between the two groups(all P ＞0.05).The increase of resistin level in group 1 was associated with UA,systolic pressure and HOMA-IR(r =0.357,0.427,0.582,all P ＜ 0.05).Conclusion The serum resistin level of patients with metabolic syndrome in Mongol population is correlated with UA,systolic pressure and insulin resistance index,and maybe play an important role in the development of metabolic syndrome.
