CAJ | 학술논문

目的探讨优化复苏集束化策略对急诊脓毒性休克患者预后的影响.方法将经急诊重症监护室(ICU)收住的脓毒性休克患者65例用数字表法随机分为治疗组(采用优化复苏集束化策略)32例和对照组(采用拯救脓毒症运动经典方法)33例.观察和比较两组患者器官衰竭评分系统(SOFA)评分的变化及血管活性药物使用时间、机械通气时间、ICU住院时间和28 d病死率.结果治疗组人选后3d、7 d SOFA评分分别为(9.1±2.5)分、(8.2±2.8)分,均低于对照组同期的(10.1 ±3.3)分、(9.5±3.1)分(=4.52、3.99,均P＜0.05)；治疗组28 d病死率为28.1％,低于对照组的48.5％(x2=12.84,P＜0.05).结论早期应用优化复苏集束化策略可以明显改善急诊脓毒性休克患者的预后.
목적 탐토우화복소집속화책략대급진농독성휴극환자예후적영향.방법 장경급진중증감호실(ICU)수주적농독성휴극환자65례용수자표법수궤분위치료조(채용우화복소집속화책략)32례화대조조(채용증구농독증운동경전방법)33례.관찰화비교량조환자기관쇠갈평분계통(SOFA)평분적변화급혈관활성약물사용시간、궤계통기시간、ICU주원시간화28 d병사솔.결과 치료조인선후3d、7 d SOFA평분분별위(9.1±2.5)분、(8.2±2.8)분,균저우대조조동기적(10.1 ±3.3)분、(9.5±3.1)분(=4.52、3.99,균P＜0.05)；치료조28 d병사솔위28.1％,저우대조조적48.5％(x2=12.84,P＜0.05).결론 조기응용우화복소집속화책략가이명현개선급진농독성휴극환자적예후.
Objective To evaluate the effects of an optimized resuscitation bundle on prognosis of emergency patients with septic shock.Methods 65 patients with septic shock,admitted into emergency intensive care unit (ICU),were randomly divided into the treatment group(treated by an optimized resuscitation bundle)and the control group(treated by surviving sepsis campaign classics methods)by using random number table.The scores of sepsis-related organ failure assessment(SOFA) scores,the vasoactive agent application times,the mechanical ventilation times,the stay days of ICU,and 28-day mortality of the two groups were observed and compared.Results 3,7 day after erollment the SOFA score of the treatment group was (9.1 ± 2.5) points,(8.2 ± 2.8) points,respectively,which was lower than that of the control group[(10.1 ± 3.3) points,(9.5 ± 3.1) points] at the same time(t =4.52,3.99,all P ＜ 0.05) ; 8-day mortality rate of the treatment group was 28.1％,which was lower than that of the control group (48.5％) (x2 =12.84,P ＜ 0.05).Conclusion Application of an early optimized resuscitation bundle can significantly improve the prognosis of emergency patients with septic shock.