中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2014年
8期
1123-1126
,共4页
重症监护病房%病原菌%耐药性
重癥鑑護病房%病原菌%耐藥性
중증감호병방%병원균%내약성
Intensive care unit%Pathogenic bacteria%Drug resistance
目的 了解医院重症监护病房(ICU)病原菌的分布及耐药性,为临床合理用药和医院感染预防控制提供依据.方法 回顾性分析2009年1月至2012年12月医院ICU分离的749株病原菌的耐药性,细菌鉴定和药敏试验采用VITEK 2 Compact全自动细菌培养鉴定仪.结果 749株病原菌中以鲍曼不动杆菌(208株,27.8％)、铜绿假单胞菌(108株,14.4％)、大肠埃希菌(96株,12.8％)、金黄色葡萄球菌(76株,10.1％)、肺炎克雷伯菌(62株,8.3％)为主;标本来源主要为痰液(503株,67.2％);耐甲氧西林金黄色葡萄球菌(MRSA)的分离率为82.9％ (63/76);耐亚胺培南铜绿假单胞菌(IRPA)的分离率为22.2％(24/108);耐碳青霉烯类抗菌药物鲍曼不动杆菌(CR-AB)的分离率为88.0％ (183/208).鲍曼不动杆菌对阿米卡星耐药率为28.6％～ 31.5％,对其它20种抗菌药物的耐药率高达81.6％～100.0％;铜绿假单胞菌对环丙沙星、左氧氟沙星、氨曲南和哌拉西林/他唑巴坦的耐药率为11.6％ ～25.0％.结论 ICU检出的病原菌中,多药耐药的现象严重,医院应加强细菌耐药性监测,合理使用抗菌药物,降低医院感染.
目的 瞭解醫院重癥鑑護病房(ICU)病原菌的分佈及耐藥性,為臨床閤理用藥和醫院感染預防控製提供依據.方法 迴顧性分析2009年1月至2012年12月醫院ICU分離的749株病原菌的耐藥性,細菌鑒定和藥敏試驗採用VITEK 2 Compact全自動細菌培養鑒定儀.結果 749株病原菌中以鮑曼不動桿菌(208株,27.8％)、銅綠假單胞菌(108株,14.4％)、大腸埃希菌(96株,12.8％)、金黃色葡萄毬菌(76株,10.1％)、肺炎剋雷伯菌(62株,8.3％)為主;標本來源主要為痰液(503株,67.2％);耐甲氧西林金黃色葡萄毬菌(MRSA)的分離率為82.9％ (63/76);耐亞胺培南銅綠假單胞菌(IRPA)的分離率為22.2％(24/108);耐碳青黴烯類抗菌藥物鮑曼不動桿菌(CR-AB)的分離率為88.0％ (183/208).鮑曼不動桿菌對阿米卡星耐藥率為28.6％～ 31.5％,對其它20種抗菌藥物的耐藥率高達81.6％～100.0％;銅綠假單胞菌對環丙沙星、左氧氟沙星、氨麯南和哌拉西林/他唑巴坦的耐藥率為11.6％ ～25.0％.結論 ICU檢齣的病原菌中,多藥耐藥的現象嚴重,醫院應加彊細菌耐藥性鑑測,閤理使用抗菌藥物,降低醫院感染.
목적 료해의원중증감호병방(ICU)병원균적분포급내약성,위림상합리용약화의원감염예방공제제공의거.방법 회고성분석2009년1월지2012년12월의원ICU분리적749주병원균적내약성,세균감정화약민시험채용VITEK 2 Compact전자동세균배양감정의.결과 749주병원균중이포만불동간균(208주,27.8％)、동록가단포균(108주,14.4％)、대장애희균(96주,12.8％)、금황색포도구균(76주,10.1％)、폐염극뢰백균(62주,8.3％)위주;표본래원주요위담액(503주,67.2％);내갑양서림금황색포도구균(MRSA)적분리솔위82.9％ (63/76);내아알배남동록가단포균(IRPA)적분리솔위22.2％(24/108);내탄청매희류항균약물포만불동간균(CR-AB)적분리솔위88.0％ (183/208).포만불동간균대아미잡성내약솔위28.6％～ 31.5％,대기타20충항균약물적내약솔고체81.6％～100.0％;동록가단포균대배병사성、좌양불사성、안곡남화고랍서림/타서파탄적내약솔위11.6％ ～25.0％.결론 ICU검출적병원균중,다약내약적현상엄중,의원응가강세균내약성감측,합리사용항균약물,강저의원감염.
Objective To understand the hospital intensive care unit(ICU) pathogenic bacteria distribution and drug resistance for providing the basis for rational drug use and hospital infection control and prevention.Methods The drug resistance of 749 strains of pathogenic bacteria the separated from ICU was analyzed from January 2009 to December 2012.VITEK 2 Compact automatic bacteria identification instrument was used to detect bacteria identification and drug sensitive test using.Results There were Acinetobacter baumannii(208 strains,27.8％),Pseudomonas aeruginosa(108 strains,14.4％),E.coli (96 strains,12.8 ％),Staphylococcus aureus (76 strains,10.1％),Klebsiella pneumoniae(62 strains,8.3％) mainly accupied in 749 strains of pathogenic bacteria.The species was mainly from sputum specimens sources (503 strains,67.2％) ; the separation rate of Methicillin-resistant staphylococcus aureus (MRSA) was 82.9％ (63/76) ; the separation rate of Imine resistance from South pseudomonas aeruginosa(IRPA) was 22.2％ (24/108) ; the separation rate of resistance to carbon penicillium alkene antimicrobial acinetobacter baumannii (CR-AB) was 88.0％ (183/208).The resistant rate of Acinetobacter baumannii to amikacin was from 28.6％ to 31.5％,the other 20 kinds of antimicrobial drug resistant rate was as high as 81.6％-100.0％ ; Pseudomonas aeruginosa to ciprofloxacin,ofloxacin,aztreonam and piperacillin/tazobactam resistant rate of 11.6％-25.0％.Conclusion Detection of pathogens in ICU,multi-drug resistance is serious,the hospital should strengthen the bacterial drug resistance monitoring,rational use of antimicrobial drugs,reduce the nosocomial infection.
