中华临床营养杂志
中華臨床營養雜誌
중화림상영양잡지
CHINESE JOURNAL OF CLINICAL NUTRITION
2013年
5期
263-266
,共4页
楼大钧%朱麒钱%叶飞%李铎%黄迪华%董海燕%斯徐伟
樓大鈞%硃麒錢%葉飛%李鐸%黃迪華%董海燕%斯徐偉
루대균%주기전%협비%리탁%황적화%동해연%사서위
代谢综合征%甘油三酯%多不饱和脂肪酸
代謝綜閤徵%甘油三酯%多不飽和脂肪痠
대사종합정%감유삼지%다불포화지방산
Metabolic syndrome%Triglyceride%Polyunsaturated fatty acid
目的 研究代谢综合征(MS)患者血脂与血清多不饱和脂肪酸(PUFA)的相关性.方法 选取2011年6月至2012年6月绍兴市人民医院住院控制血糖的74例代谢综合征患者,以同期门诊体检的62例为正常对照,采用酶法测定血脂,高效气相色谱法测定血清磷脂脂肪酸谱组分,并计算血清PUFA百分含量.结果 MS组甘油三醋(TG)水平明显高于对照组[(2.0±0.8) mmol/L比(1.3±0.5)mmol/L,P=0.000].MS组n-3 PUFA百分含量(9.8％±2.2％比11.1％±2.4％,P =0.002)、n-6 PUFA百分含量(35.4％±6.7％比39.5％±7.8％,P=0.009)、总PUFA百分含量均明显低于对照组(45.2％±8.9％比50.6％±10.1％,P=0.000).相关性分析显示TG浓度水平与n-3 PUFA、总PUFA百分含量呈负相关(r=-0.42,P=0.008；r=-0.23,P=0.013).结论 MS患者n-3 PUFA、n-6 PUFA、PUFA明显低于健康对照,其血清TG水平与血清PUFA呈负相关.
目的 研究代謝綜閤徵(MS)患者血脂與血清多不飽和脂肪痠(PUFA)的相關性.方法 選取2011年6月至2012年6月紹興市人民醫院住院控製血糖的74例代謝綜閤徵患者,以同期門診體檢的62例為正常對照,採用酶法測定血脂,高效氣相色譜法測定血清燐脂脂肪痠譜組分,併計算血清PUFA百分含量.結果 MS組甘油三醋(TG)水平明顯高于對照組[(2.0±0.8) mmol/L比(1.3±0.5)mmol/L,P=0.000].MS組n-3 PUFA百分含量(9.8％±2.2％比11.1％±2.4％,P =0.002)、n-6 PUFA百分含量(35.4％±6.7％比39.5％±7.8％,P=0.009)、總PUFA百分含量均明顯低于對照組(45.2％±8.9％比50.6％±10.1％,P=0.000).相關性分析顯示TG濃度水平與n-3 PUFA、總PUFA百分含量呈負相關(r=-0.42,P=0.008；r=-0.23,P=0.013).結論 MS患者n-3 PUFA、n-6 PUFA、PUFA明顯低于健康對照,其血清TG水平與血清PUFA呈負相關.
목적 연구대사종합정(MS)환자혈지여혈청다불포화지방산(PUFA)적상관성.방법 선취2011년6월지2012년6월소흥시인민의원주원공제혈당적74례대사종합정환자,이동기문진체검적62례위정상대조,채용매법측정혈지,고효기상색보법측정혈청린지지방산보조분,병계산혈청PUFA백분함량.결과 MS조감유삼작(TG)수평명현고우대조조[(2.0±0.8) mmol/L비(1.3±0.5)mmol/L,P=0.000].MS조n-3 PUFA백분함량(9.8％±2.2％비11.1％±2.4％,P =0.002)、n-6 PUFA백분함량(35.4％±6.7％비39.5％±7.8％,P=0.009)、총PUFA백분함량균명현저우대조조(45.2％±8.9％비50.6％±10.1％,P=0.000).상관성분석현시TG농도수평여n-3 PUFA、총PUFA백분함량정부상관(r=-0.42,P=0.008；r=-0.23,P=0.013).결론 MS환자n-3 PUFA、n-6 PUFA、PUFA명현저우건강대조,기혈청TG수평여혈청PUFA정부상관.
Objective To investigate the relationship between triglyceride and serum polyunsaturated fatty acid (PUFA) in patients with metabolic syndrome (MS).Methods Totally 74 MS patients (MS group) and 62 healthy subjects (normal control group,NC group) were recruited from June 2011 to June 2012 in Shaoxing People's Hospital.Serum phospholipid fatty acid profiles were analyzed with capillary gas chromatography.Serum lipids were measured by enzymatic assay.Results The triglyceride concentration was significantly higher in MS group than that in NC group [(2.0 ±0.8) mmol/L vs.(1.3 ±0.5) mmol/L,P=0.000].The levels of n-3 PUFA,n-6 PUFA,and PUFA were significantly lower in MS group than those in NC group (9.8％ ±2.2％ vs.11.1％ ±2.4％,P=0.002; 35.4％ ±6.7％ vs.39.5％ ±7.8％,P=0.009; 45.2％ ±8.9％ vs.50.6％ ±10.1％,P =0.000).Triglyceride concentration was inversely correlated with n-3 PUFA and PUFA levels (r =-0.42,P =0.008 ; r =-0.23,P =0.013).Conclusions n-3 PUFA,n-6 PUFA,and PUFA decrease in MS patients.Triglyceride concentration is inversely correlated with PUFA.
