CAJ | 학술논문

目的观察纤维蛋白黏合剂联合自体结膜移植治疗手术源性浅层巩膜坏死手术的临床效果.方法采用非随机回顾性系列病例研究.选择2007年6月至2011年6月在厦门大学附属厦门眼科中心住院的14例(14只限)不同病因手术源性浅层巩膜坏死患者,根据病灶的大小和形状,采用纤维蛋白黏合剂辅助自体结膜移植术治疗,术后随访6～12个月,观察患者术后结膜植片、巩膜情况及并发症.结果 14例患者结膜瓣均成功贴附巩膜生长良好,术后2～4周不适症状得到完全缓解.3只眼滴用糖皮质激素后曾出现眼压升高,经及时改用普拉洛芬滴眼后眼压控制正常.与术前相比,术后3眼(21.43％)最佳矫正视力提高,11只眼不变(78.57％).随访1年,所有术眼无巩膜坏死复发.结论纤维蛋白黏合剂辅助自体结膜移植治疗手术源性浅层巩膜坏死是一种较为简便、安全、有效的手术方式.
목적 관찰섬유단백점합제연합자체결막이식치료수술원성천층공막배사수술적림상효과.방법 채용비수궤회고성계렬병례연구.선택2007년6월지2011년6월재하문대학부속하문안과중심주원적14례(14지한)불동병인수술원성천층공막배사환자,근거병조적대소화형상,채용섬유단백점합제보조자체결막이식술치료,술후수방6～12개월,관찰환자술후결막식편、공막정황급병발증.결과 14례환자결막판균성공첩부공막생장량호,술후2～4주불괄증상득도완전완해.3지안적용당피질격소후증출현안압승고,경급시개용보랍락분적안후안압공제정상.여술전상비,술후3안(21.43％)최가교정시력제고,11지안불변(78.57％).수방1년,소유술안무공막배사복발.결론 섬유단백점합제보조자체결막이식치료수술원성천층공막배사시일충교위간편、안전、유효적수술방식.
Objective To observe the clinical effect of fibrin glue (FG) with conjunctival autograft in the treatment of surgically induced necrotizing scleritis using conjunctival autograft transplantation.Methods Noncomparative interventional case series.In 14 eyes of 14 patients with surgically induced necrotizing scleritis (SINS),fibrin glue (FG) with conjunctival autograft was performed.Postoperatively,the graft status and postoperative complications were recorded.Results After surgery,no autograft dislocation and necrotizing scleritis occurred during the follow-up period.All symptoms and signs steadily reduced,except 3 cases with elevated intraocular pressure postoperatively,3 patients had improved best corrected visual acuity while 1l patients had the same BCVA.Conclusions Fibrin glue (FG) with conjunctival autograft surgery for SINS is feasible,technically easy,safe and effective.It can be one of the surgical treatment options for SINS.