中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2013年
3期
267-269
,共3页
杨丽亚%韩梅%解士勇%杨凯转%徐延山
楊麗亞%韓梅%解士勇%楊凱轉%徐延山
양려아%한매%해사용%양개전%서연산
光感受器内外节层%缺失%病因%相干光断层扫描
光感受器內外節層%缺失%病因%相榦光斷層掃描
광감수기내외절층%결실%병인%상간광단층소묘
Photoreceptor inner/outer segment (IS/OS) layer%Deletion%Etiology%Optical coherence tomography
目的 了解黄斑区光感受器内外节(IS/OS)层局部微小缺失的常见病因及相干光断层扫描(OCT)特征.方法 临床病例回顾性研究.回顾性分析2009年6月到2012年1月在天津市眼科医院门诊患者资料,OCT示患眼黄斑区IS/OS层局部微小缺失、中断,视网膜缺失区域外不伴有其他形态学改变,从患者的病历资料中提取病史及最佳矫正视力(BCVA)、眼底彩色照相、OCT、FFA等检查结果.结果 90例98只眼.视力均有不同程度下降、视物模糊或伴眼前黑影.原因未明者47例47只眼(48.0％),外伤史者17例18只眼(18.4％),黄斑裂孔术后者7例7只眼(7.1％),眼底出血吸收后者5例5眼(5.1％),电焊伤者4例8眼(8.2％),激光损伤者3例4眼(4.1％),电击伤者2例3只眼(3.1％),高度近视者2例2只眼(2.0％),中心性浆液性脉络膜视网膜病变(中浆)恢复后者1例1只眼(1.0％),合并青光眼者1例2只眼(2.0％),合并糖尿病者1例1只眼(1.0％).眼底彩色照相显示黄斑区出现圆形或椭圆形、边界不清的暗黄色改变者72例80只眼(81.6％),未发现明显改变者18例18只眼(18.4％).OCT示黄斑区均可见IS/OS层局部缺失、中断,视网膜缺失区域外不伴有其他形态学改变；37例行荧光素眼底血管造影(FFA)检查,未见明显异常.结论 多种因素均可导致黄斑区IS/OS层部分缺失,致病因素目前尚未完全明确；视功能均有不同程度损害；OCT检查能够明确病变部位,对临床诊疗具有指导意义.
目的 瞭解黃斑區光感受器內外節(IS/OS)層跼部微小缺失的常見病因及相榦光斷層掃描(OCT)特徵.方法 臨床病例迴顧性研究.迴顧性分析2009年6月到2012年1月在天津市眼科醫院門診患者資料,OCT示患眼黃斑區IS/OS層跼部微小缺失、中斷,視網膜缺失區域外不伴有其他形態學改變,從患者的病歷資料中提取病史及最佳矯正視力(BCVA)、眼底綵色照相、OCT、FFA等檢查結果.結果 90例98隻眼.視力均有不同程度下降、視物模糊或伴眼前黑影.原因未明者47例47隻眼(48.0％),外傷史者17例18隻眼(18.4％),黃斑裂孔術後者7例7隻眼(7.1％),眼底齣血吸收後者5例5眼(5.1％),電銲傷者4例8眼(8.2％),激光損傷者3例4眼(4.1％),電擊傷者2例3隻眼(3.1％),高度近視者2例2隻眼(2.0％),中心性漿液性脈絡膜視網膜病變(中漿)恢複後者1例1隻眼(1.0％),閤併青光眼者1例2隻眼(2.0％),閤併糖尿病者1例1隻眼(1.0％).眼底綵色照相顯示黃斑區齣現圓形或橢圓形、邊界不清的暗黃色改變者72例80隻眼(81.6％),未髮現明顯改變者18例18隻眼(18.4％).OCT示黃斑區均可見IS/OS層跼部缺失、中斷,視網膜缺失區域外不伴有其他形態學改變；37例行熒光素眼底血管造影(FFA)檢查,未見明顯異常.結論 多種因素均可導緻黃斑區IS/OS層部分缺失,緻病因素目前尚未完全明確；視功能均有不同程度損害；OCT檢查能夠明確病變部位,對臨床診療具有指導意義.
목적 료해황반구광감수기내외절(IS/OS)층국부미소결실적상견병인급상간광단층소묘(OCT)특정.방법 림상병례회고성연구.회고성분석2009년6월도2012년1월재천진시안과의원문진환자자료,OCT시환안황반구IS/OS층국부미소결실、중단,시망막결실구역외불반유기타형태학개변,종환자적병력자료중제취병사급최가교정시력(BCVA)、안저채색조상、OCT、FFA등검사결과.결과 90례98지안.시력균유불동정도하강、시물모호혹반안전흑영.원인미명자47례47지안(48.0％),외상사자17례18지안(18.4％),황반렬공술후자7례7지안(7.1％),안저출혈흡수후자5례5안(5.1％),전한상자4례8안(8.2％),격광손상자3례4안(4.1％),전격상자2례3지안(3.1％),고도근시자2례2지안(2.0％),중심성장액성맥락막시망막병변(중장)회복후자1례1지안(1.0％),합병청광안자1례2지안(2.0％),합병당뇨병자1례1지안(1.0％).안저채색조상현시황반구출현원형혹타원형、변계불청적암황색개변자72례80지안(81.6％),미발현명현개변자18례18지안(18.4％).OCT시황반구균가견IS/OS층국부결실、중단,시망막결실구역외불반유기타형태학개변；37례행형광소안저혈관조영(FFA)검사,미견명현이상.결론 다충인소균가도치황반구IS/OS층부분결실,치병인소목전상미완전명학；시공능균유불동정도손해；OCT검사능구명학병변부위,대림상진료구유지도의의.
ObJective To study the common etiology and optical coherence tomography (OCT) characteristics of the photoreceptor inner/outer segment (IS/OS) layer local deletion in macular.Methods The clinical data of outpatients from June 2009 to January 2012 in Tianjin Eye Hospital were summarized and analyzed retrospectively,and their OCT examination revealed that the IS/OS layer local deletion and break in macular was not associated with other morphological changes outside the region of retina missing.The history,vision,fundus photography and OCT examination results were extracted from the patient's medical records.Results Ninety-eight eyes of 90 cases showed that visual acuity decreased with blurred vision or immediate shadow.Forty-seven eyes of 47 cases (48.0％) had no clear etiological factors; 18 eyes of 17 cases (18.4％) associated with other types of traumatic retinopathy; 7 eyes of 7 cases (7.1％) had macular hole surgery before; 5 eyes of 5 cases (5.1％) had subhyaloid hemorrhage; 4 cases (8.2％) were welders,both eyes injuring; 4eyes of 3 cases (4.1％) were laser injuries; 3 eyes of 2 cases (3.1％) had recent electrical injuries; 2 eyes of 2 cases (2.0％) were high myopia; 1 eye of 1 case (1.0％) restored from central serous chorioretinopathy; 2 eyes of 1 case (1.0％) were with glaucoma and l eye of l case was with diabetes.Fundus photography showed that 80 eyes of 72 cases could be found round or oval,ill-defined dark yellow changes in macular and the others were without significant changes.All the eyes' OCT examination revealed that the IS/OS layer local deletion and break in macular was not associated with other morphological changes outside the region of retina missing.Conclusions The causes of IS/OS layer local deletion and break in macular are very complicate,and many of them are indefinite.The location can impair visual function more or less.It is possible to use OCT to precisely locate diseased regions,thus providing guidance to the clinical diagnosis and treatment.
