CAJ | 학술논문

目的研究弱视儿童多焦视觉诱发电位(mVEP)特征峰的变化.方法采用德国Roland公司生产的RETIScan3.20多焦视觉电生理仪,对30例正常对照组和78例弱视患者进行mVEP的检测,进行视网膜不同区域的比较.结果 (1)重度弱视组特征峰的振幅反应密度(646.78±29.53) nV.deg-2,低于正常对照组(835.29±11.02) nV·deg-2,重度弱视组特征峰隐含值(115.1±10.2) ms,长于正常对照组(103.8±11.1) ms,有统计学意义.轻度弱视组和中度弱视组特征峰振幅反应密度在第1、2、3环中降低,有统计学意义(P＜0.05),第4、5、6环不延长,差异无统计学意义(P＞0.05).(2)重度弱视组鼻侧视网膜特征峰隐含值(110.7±3.8) ms,长于正常对照组鼻侧视网膜特征峰隐含值(102.9±2.1) ms,差异有统计学意义；重度弱视组颞侧视网膜特征峰隐含值(107.2±4.5) ms,长于正常对照组颞侧视网膜特征峰隐含值(103.3±1.9)ms,差异有统计学意义；轻度和中度弱视组特征峰隐含值在第1环延长,差异有统计学意义(P＜0.05)；3、重度弱视组上半侧视网膜特征峰隐含值(110.3±4.1) ms,长于正常对照组下半侧视网膜特征峰隐含值(105.2±2.9) ms,差异有统计学意义.重度弱视组下半侧视网膜特征峰隐含值(109.2±4.8) ms,长于正常对照组下半侧视网膜特征峰隐含值(106.4±2.2) ms,差异有统计学意义.结论弱视的mVEP结果存在特征性改变,“中枢发生学说”与“外周发生学说”相互联系,互为补充.
목적 연구약시인동다초시각유발전위(mVEP)특정봉적변화.방법 채용덕국Roland공사생산적RETIScan3.20다초시각전생리의,대30례정상대조조화78례약시환자진행mVEP적검측,진행시망막불동구역적비교.결과 (1)중도약시조특정봉적진폭반응밀도(646.78±29.53) nV.deg-2,저우정상대조조(835.29±11.02) nV·deg-2,중도약시조특정봉은함치(115.1±10.2) ms,장우정상대조조(103.8±11.1) ms,유통계학의의.경도약시조화중도약시조특정봉진폭반응밀도재제1、2、3배중강저,유통계학의의(P＜0.05),제4、5、6배불연장,차이무통계학의의(P＞0.05).(2)중도약시조비측시망막특정봉은함치(110.7±3.8) ms,장우정상대조조비측시망막특정봉은함치(102.9±2.1) ms,차이유통계학의의；중도약시조섭측시망막특정봉은함치(107.2±4.5) ms,장우정상대조조섭측시망막특정봉은함치(103.3±1.9)ms,차이유통계학의의；경도화중도약시조특정봉은함치재제1배연장,차이유통계학의의(P＜0.05)；3、중도약시조상반측시망막특정봉은함치(110.3±4.1) ms,장우정상대조조하반측시망막특정봉은함치(105.2±2.9) ms,차이유통계학의의.중도약시조하반측시망막특정봉은함치(109.2±4.8) ms,장우정상대조조하반측시망막특정봉은함치(106.4±2.2) ms,차이유통계학의의.결론 약시적mVEP결과존재특정성개변,“중추발생학설”여“외주발생학설”상호련계,호위보충.
ObJective To study the characteristic changes of multifocal VEP in amblyopia's children.Methods The mVEP of both eyes of 78 amblyopias were recorded by Roland RETIScan 3.20 multiofcal electrophysiological system made by Germany Roland Company.The changes in different retinal area were investigated by comparing with the normal subjects.Results 1.The amplitude densities in the serious amblyopias group was about 646.78±29.53 nV.deg-2,and it was lowered than the densities of normal group,the latencies in the serious amblyopia group was about 115.1±10.2 ms,and it was more prolong than the latencies of the normal group.The amplitude densities in the Mild and moderate amblyopia groups (1,2,3 ring) was reduced,with statistical significance (P ＜0.05); but the amplitude densities in 4,5,6 ring was extended,without statistical significance (P ＞0.05).2.The latencies in the nasal retinal hemifield of serious amblyopia group was about 110.7±3.8 ms,and it was more prolong than the latencies of the nasal retinal hemifield of normal group,especially significantly in area.The latencies in the temporal retinal hemifield of serious amblyopia group was about 107.2±4.5ms,and it was more prolong than the latencies of the temporal retinal hemifield of normal group,especially significantly in area.The latencies in the mild and moderate amblyopia in first ring was extended,with statistical significance (P ＜0.05); 3.The latencies in the higher retinal hemifield of serious amblyopia group was about 105.2±2.9ms,and it was more prolong than the latencies of the higher retinal hemifield of normal group,especially significantly in area.The latencies in the lower retinal hemifield of serious amblyopia group was about 109.2±4.8ms,and it was more prolong than the latencies of the lower retinal hemifield of normal group,especially significantly in area.Conclusions The results of amblyopia mVEP has characteristic change,"central place theory" and "outside theory" are interrelated and complemented each other.