CAJ | 학술논문

目的研究矫正散光的有晶状体眼后房型人工晶状体(toric implantable contact lens,TICL)矫正高度近视合并散光的有效性及可预测性.方法对22例(31只眼)高度近视患者行TICL植入术,术前散光度数为(-1.50～-4.75)D之间.记录术前及术后1、3个月的裸眼视力、最佳矫正视力、屈光度、眼压、角膜内皮细胞密度等.结果所有患者成功植入TICL,手术前后裸眼视力(Log-MAR)分别为1.16±0.31、0.23±0.17、0.25±0.18,手术前后最佳矫正视力(LogMAR)分别为0.26±0.17、0.13±0.13、0.12±0.13,差异有统计学意义(P＜0.01);植入TICL预计矫正等效球镜度数与术后1个月实际矫正度数一致(r=-0.938,P=0.000),预计矫正等效球镜度数与术后3个月实际矫正度数一致(r =-0.946,P=0.000);植入TICL预计矫正散光度数与术后1个月实际矫正散光度数J0一致(r=-0.526,P=0.002),与术后3个月实际矫正散光度数J0一致(r=-0.542,P=0.002).预计矫正散光度数与术后1个月实际矫正散光度数J45一致(r=-0.710,P=0.000),与术后3个月实际矫正散光度数J45一致(r =-0.878,P=0.000).手术前后角膜内皮细胞密度分别为(2933.65±263.07)、(2899.35±256.84)、(2877.13±274.55)个/mm2,差异无统计学意义.结论 TICL矫正高度近视合并散光有较好的有效性及可预测性,长期疗效有待进一步观察.
목적 연구교정산광적유정상체안후방형인공정상체(toric implantable contact lens,TICL)교정고도근시합병산광적유효성급가예측성.방법 대22례(31지안)고도근시환자행TICL식입술,술전산광도수위(-1.50～-4.75)D지간.기록술전급술후1、3개월적라안시력、최가교정시력、굴광도、안압、각막내피세포밀도등.결과 소유환자성공식입TICL,수술전후라안시력(Log-MAR)분별위1.16±0.31、0.23±0.17、0.25±0.18,수술전후최가교정시력(LogMAR)분별위0.26±0.17、0.13±0.13、0.12±0.13,차이유통계학의의(P＜0.01);식입TICL예계교정등효구경도수여술후1개월실제교정도수일치(r=-0.938,P=0.000),예계교정등효구경도수여술후3개월실제교정도수일치(r =-0.946,P=0.000);식입TICL예계교정산광도수여술후1개월실제교정산광도수J0일치(r=-0.526,P=0.002),여술후3개월실제교정산광도수J0일치(r=-0.542,P=0.002).예계교정산광도수여술후1개월실제교정산광도수J45일치(r=-0.710,P=0.000),여술후3개월실제교정산광도수J45일치(r =-0.878,P=0.000).수술전후각막내피세포밀도분별위(2933.65±263.07)、(2899.35±256.84)、(2877.13±274.55)개/mm2,차이무통계학의의.결론 TICL교정고도근시합병산광유교호적유효성급가예측성,장기료효유대진일보관찰.
Objective To evaluate the efficacy and safety of posterior chamber phakic intraocular lens toric implantable contact lens (TICL) for the correction high myopia with a astigmatism.Methods Posterior chamber phakic toric intraocular lens implantation was performed in 31 eyes of 22 patients with high myopia with a astigmatism.The patients with a astigmatism (-1.50 ～-4.75)D.The clinical examinations included uncorrected visual acuity (UCVA),best corrected visual acuity (BCVA),astigmatism power,intraocular pressure and cornea endothelial cell density before and after surgery.Results TICL were implanted successfully in all the operative eyes.The average UCVA was 1.16+0.31,0.23±0.17,0.25±0.18 at preoperative and postoperative 1 month,3 months respectively.The average BCVA was 0.26±0.17,0.13±0.13,0.12±0.13 at preoperative and postoperative 1 month,3 months respectively,showed a significant difference (P ＜0.01).At 1 month the expected correction of spherical equivalent degree corresponded with actual (r =-0.938,P =0.000),also at 3 months (r =-0.946,P=0.000); At 1 month the expected correction of astigmatism degree J0 corresponded with actual (r =-0.526,P =0.002),also at 3 months (r =-0.542,P =0.002).At 1 month the expected correction of astigmatism degree J45 corresponded with actual (r =-0.710,P =0.000),also at 3 months (r =-0.878,P =0.000).The average cornea endothelial cell density was (2933.65±263.07) cells/mm2 before operation and (2899.35±256.84),(2877.13±274.55) cells/rmm2 at 1 month,3 months after operation,showed no significant difference.Conclusions TICL implantation for high myopia with a astigmatism is predictable,safe and effective.A long term evaluation of effectiveness and safety for this phakic IOL should be performed.