中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2014年
1期
49-52
,共4页
中心性浆液性脉络膜视网膜病变%光学相干断层扫描%视野
中心性漿液性脈絡膜視網膜病變%光學相榦斷層掃描%視野
중심성장액성맥락막시망막병변%광학상간단층소묘%시야
Central serous chorioretinopathy%Optical coherence tomography%Visual field
目的 观察中心性浆液性脉络膜视网膜病变(central serous chorioretinopathy,CSC)的光学相干断层扫描(optical coherence tomography,OCT)和视野参数的特征及相关性.方法 临床病例系列研究.对2012年8～12月在天津市眼科医院就诊的急性期CSC患者30例(30只眼),并将其对侧眼作为正常对照组,进行OCT定量测量黄斑区视网膜厚度,Humphrey-750i型自动视野计分析黄斑10°的平均光敏感度(mean sensitivity,MS)、平均偏差(mean deviation,MD)和黄斑中心凹光敏感度(Foveal sensitivity).采用统计学软件分析数据,评价急性期CSC患者黄斑区形态与功能的相关性.结果 CSC患眼的直径1 mm的中央区视网膜厚度、3 mm旁中心凹视网膜平均厚度和直径5 mm的中心凹周围平均视网膜厚度与对侧眼比较,差异均有统计学意义(P＜0.05),CSC患眼的MS、MD和Fovealsensitivity与对侧眼比较,差异均有统计学意义(P＜0.05),患眼组的直径1 mm的中央区视网膜厚度与黄斑中心凹光敏感度差异有统计学意义(r =-0.546,P=0.002)；3mm旁中心凹视网膜平均厚度与MS差异有统计学意义(r=-0.631,P=0.000),与MD比较差异有统计学意义(r=-0.493,P=0.007,P＜0.05).结论 急性期CSC患者的OCT横断面图像可以清楚显示眼底后极部黄斑区或附近视网膜神经上皮层局限性浆液性脱离,伴或不伴有视网膜色素上皮的脱离；视野检查常见中心暗点,呈圆形或椭圆形.OCT与视野相结合能更全面评估中心性浆液性脉络膜视网膜病变微结构及与结构变化相应的功能改变,更好地了解CSC急性期形态与视觉功能的变化.
目的 觀察中心性漿液性脈絡膜視網膜病變(central serous chorioretinopathy,CSC)的光學相榦斷層掃描(optical coherence tomography,OCT)和視野參數的特徵及相關性.方法 臨床病例繫列研究.對2012年8～12月在天津市眼科醫院就診的急性期CSC患者30例(30隻眼),併將其對側眼作為正常對照組,進行OCT定量測量黃斑區視網膜厚度,Humphrey-750i型自動視野計分析黃斑10°的平均光敏感度(mean sensitivity,MS)、平均偏差(mean deviation,MD)和黃斑中心凹光敏感度(Foveal sensitivity).採用統計學軟件分析數據,評價急性期CSC患者黃斑區形態與功能的相關性.結果 CSC患眼的直徑1 mm的中央區視網膜厚度、3 mm徬中心凹視網膜平均厚度和直徑5 mm的中心凹週圍平均視網膜厚度與對側眼比較,差異均有統計學意義(P＜0.05),CSC患眼的MS、MD和Fovealsensitivity與對側眼比較,差異均有統計學意義(P＜0.05),患眼組的直徑1 mm的中央區視網膜厚度與黃斑中心凹光敏感度差異有統計學意義(r =-0.546,P=0.002)；3mm徬中心凹視網膜平均厚度與MS差異有統計學意義(r=-0.631,P=0.000),與MD比較差異有統計學意義(r=-0.493,P=0.007,P＜0.05).結論 急性期CSC患者的OCT橫斷麵圖像可以清楚顯示眼底後極部黃斑區或附近視網膜神經上皮層跼限性漿液性脫離,伴或不伴有視網膜色素上皮的脫離；視野檢查常見中心暗點,呈圓形或橢圓形.OCT與視野相結閤能更全麵評估中心性漿液性脈絡膜視網膜病變微結構及與結構變化相應的功能改變,更好地瞭解CSC急性期形態與視覺功能的變化.
목적 관찰중심성장액성맥락막시망막병변(central serous chorioretinopathy,CSC)적광학상간단층소묘(optical coherence tomography,OCT)화시야삼수적특정급상관성.방법 림상병례계렬연구.대2012년8～12월재천진시안과의원취진적급성기CSC환자30례(30지안),병장기대측안작위정상대조조,진행OCT정량측량황반구시망막후도,Humphrey-750i형자동시야계분석황반10°적평균광민감도(mean sensitivity,MS)、평균편차(mean deviation,MD)화황반중심요광민감도(Foveal sensitivity).채용통계학연건분석수거,평개급성기CSC환자황반구형태여공능적상관성.결과 CSC환안적직경1 mm적중앙구시망막후도、3 mm방중심요시망막평균후도화직경5 mm적중심요주위평균시망막후도여대측안비교,차이균유통계학의의(P＜0.05),CSC환안적MS、MD화Fovealsensitivity여대측안비교,차이균유통계학의의(P＜0.05),환안조적직경1 mm적중앙구시망막후도여황반중심요광민감도차이유통계학의의(r =-0.546,P=0.002)；3mm방중심요시망막평균후도여MS차이유통계학의의(r=-0.631,P=0.000),여MD비교차이유통계학의의(r=-0.493,P=0.007,P＜0.05).결론 급성기CSC환자적OCT횡단면도상가이청초현시안저후겁부황반구혹부근시망막신경상피층국한성장액성탈리,반혹불반유시망막색소상피적탈리；시야검사상견중심암점,정원형혹타원형.OCT여시야상결합능경전면평고중심성장액성맥락막시망막병변미결구급여결구변화상응적공능개변,경호지료해CSC급성기형태여시각공능적변화.
Objective To evaluate the characteristics of and the association between the optical coherence tomography (OCT) results and visual field index for acute central serous chorioretinopathy (CSC).Methods Thirty patients (30 eyes) suffering acute CSC were selected randomly and fellow eyes were as normal control group.Optical coherence tomography (OCT) examination and visual field test were applied to each group:OCT for retinal macular thickness and Humphrey-750i automated perimeter for the mean sensitivity (MS),mean deviation (MD) as well as foveal sensitivity of macular (10°).The relationship between the results of macular morphology and function were analyzed by SPSS.Results The OCT scan showed that the comparison of the average retinal thickness in the central lmm diameter area,the average thickness of macula central fovea for 3mm paracentral and the average retinal thickness in the macula central fovea of 5mm pericentral between affected and fellow eyes had statistical significance (P ＜0.05).The visual field test showed that the comparison of the MS,MD and foveal sensitivity between affected and fellow eyes had statistical significance (P ＜0.05).The average retinal thickness in the central l mm diameter area affected eyes was associated with the negativeness of central light sensitivity (r =-0.546,P =0.002),and the average thickness of macula central fovea for 3mm paracentral was associated with the negativeness of MS (r =-0.631,P =0.000),also associated with the negativeness of MD (r =-0.493,P =0.007).In cross-sectional images of OCT,it can be clearly demonstrated that the morphological changes of the localized serous neuroepithelial detachment with or without the pigment epithelium detachment at macular area; visual field provides round or oval central scotoma for macular (10°) of CSC patients.Conclusions The association of OCT and visual field develops a more comprehensive evaluation for the transitions of relevant functions in structure and micro-structure changes of CSC,also can provide a better perception of changes in morphological and visual functions of acute CSC eyes.
