中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2014年
3期
282-285
,共4页
赵桂玲%陈剑%庞燕华%周舟%梁德茂%朱敏怡%黎宗汉
趙桂玲%陳劍%龐燕華%週舟%樑德茂%硃敏怡%黎宗漢
조계령%진검%방연화%주주%량덕무%주민이%려종한
频域OCT%视网膜神经纤维层厚度%近视眼
頻域OCT%視網膜神經纖維層厚度%近視眼
빈역OCT%시망막신경섬유층후도%근시안
Optical coherence tomography%Retinal nerve fiber layer thickness%Myopia
目的 以光学相干断层成像(optical coherence tomography,OCT)分析青年人正视眼和不同屈光度的视网膜神经纤维层(retinal nerve fiber layer,RNFL)厚度及视盘参数的差异.方法 临床病例系列研究.对2012年3月至2013年4月在广州医学院志愿参加研究的青年人110名220只眼.全部使用OCT的3D模式进行正视眼和不同程度近视眼的RNFL厚度及视盘参数检测.结果 18～27岁的青年人110名.中高度近视与正视眼相比,全周平均和鼻侧、上方、下方RNFL厚度都明显变薄,颞侧明显变厚,差异有统计学意义(P＜0.05).以上各部位的RNFL厚度在高度近视眼比正视眼相差分别为8.53 μm (7.77％),14.71 μm (19.04％),11.96 μm (8.97％),18.2 μm (12.78％)和-10.37 μm(-12.07％).各种程度的近视眼与正视眼相比,视盘面积等各项参数均变小,除盘缘面积和盘缘容积外差异均有统计学意义(P＜0.05).结论 近视眼的RNFL厚度比正视眼薄,鼻侧变化最早也最大.上方和下方相继变薄,同时颞侧在增厚.近视眼视盘参数均变小.
目的 以光學相榦斷層成像(optical coherence tomography,OCT)分析青年人正視眼和不同屈光度的視網膜神經纖維層(retinal nerve fiber layer,RNFL)厚度及視盤參數的差異.方法 臨床病例繫列研究.對2012年3月至2013年4月在廣州醫學院誌願參加研究的青年人110名220隻眼.全部使用OCT的3D模式進行正視眼和不同程度近視眼的RNFL厚度及視盤參數檢測.結果 18～27歲的青年人110名.中高度近視與正視眼相比,全週平均和鼻側、上方、下方RNFL厚度都明顯變薄,顳側明顯變厚,差異有統計學意義(P＜0.05).以上各部位的RNFL厚度在高度近視眼比正視眼相差分彆為8.53 μm (7.77％),14.71 μm (19.04％),11.96 μm (8.97％),18.2 μm (12.78％)和-10.37 μm(-12.07％).各種程度的近視眼與正視眼相比,視盤麵積等各項參數均變小,除盤緣麵積和盤緣容積外差異均有統計學意義(P＜0.05).結論 近視眼的RNFL厚度比正視眼薄,鼻側變化最早也最大.上方和下方相繼變薄,同時顳側在增厚.近視眼視盤參數均變小.
목적 이광학상간단층성상(optical coherence tomography,OCT)분석청년인정시안화불동굴광도적시망막신경섬유층(retinal nerve fiber layer,RNFL)후도급시반삼수적차이.방법 림상병례계렬연구.대2012년3월지2013년4월재엄주의학원지원삼가연구적청년인110명220지안.전부사용OCT적3D모식진행정시안화불동정도근시안적RNFL후도급시반삼수검측.결과 18～27세적청년인110명.중고도근시여정시안상비,전주평균화비측、상방、하방RNFL후도도명현변박,섭측명현변후,차이유통계학의의(P＜0.05).이상각부위적RNFL후도재고도근시안비정시안상차분별위8.53 μm (7.77％),14.71 μm (19.04％),11.96 μm (8.97％),18.2 μm (12.78％)화-10.37 μm(-12.07％).각충정도적근시안여정시안상비,시반면적등각항삼수균변소,제반연면적화반연용적외차이균유통계학의의(P＜0.05).결론 근시안적RNFL후도비정시안박,비측변화최조야최대.상방화하방상계변박,동시섭측재증후.근시안시반삼수균변소.
Objective To study the characteristics and clinical significance of retinal nerve fiber layer (RNFL) thickness and optic nerve head (ONH) parameters along with an increase of myopia degree.Methods According to the myopic degree,110 subjects were divided into 4 groups:normal,slight,medium and high myopic groups.Optical coherence tomography (OCT) was used to measure the RNFL thickness and ONH parameters.Each subject had 3D scans on the ONH with 6× 6mm (512×128).The mean and different quadrants RNFL thickness and ONH parameters in different groups were analyzed.Results Compared with normal groups,the mean RNFL thicknesses in all myopic groups were significantly thinner.The change occurred first in nasal quadrant.RNFL thicknesses in high myopic groups were significantly thinner in nasal,inferior and superior quadrant.However,temporal quadrant was significantly thicker.Compared with normal groups,ONH parameters in every myopic group were smaller.Except Rim Area and Rim Volume,all parameters were significantly smaller.Conclusions The mean RNFL thickness in myopic groups is thinner and thinner along with an increase of myopia degree.Different from others,temporal quadrant is thicker.Except Rim Area and Rim Volume,all ONH parameters are significantly smaller.Above mentioned features have the clinical significance for diagnosing disease.
