中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2014年
4期
478-480
,共3页
纪丽君%孙景莹%梁俊芳%戎君%赵俊颖
紀麗君%孫景瑩%樑俊芳%戎君%趙俊穎
기려군%손경형%량준방%융군%조준영
糖尿病视网膜病变%空腹血糖%餐后2h血糖%糖化血清白蛋白%糖化血红蛋白
糖尿病視網膜病變%空腹血糖%餐後2h血糖%糖化血清白蛋白%糖化血紅蛋白
당뇨병시망막병변%공복혈당%찬후2h혈당%당화혈청백단백%당화혈홍단백
Diabetic retinopathy%Fasting blood glucose%2h postprandial blood glucose%Glycated Albumin(GA)%Glycosylated hemoglobin (HbAlc)
目的 探讨糖尿病视网膜病变患者与其血糖控制指标的关系.方法 选取2型糖尿病患者175例,按眼底变化分为3组.其中糖尿病正常眼底(NDR)组45例,非增生性糖尿病视网膜病变(NPDR)组87例,增生性糖尿病视网膜病变(PDR)组43例.检测其空腹血糖(FBG)、餐后2h血糖(2hPBG)、糖化血清白蛋白(GA)及糖化血红蛋白(HbA1c),并相应行眼底检查.结果 与NDR组相比较,NPDR、PDR组GA、HbA1c升高差异有统计学意义(P<0.05),而在NPDR组与PDR组比较差异无统计学意义(P >0.05);NPDR组中2hPBG水平较NDR组升高差异有统计学意义(P<0.05),而FBG水平DR组与NDR组差异无统计学意义(P>0.05).结论 血糖波动与2型糖尿病视网膜病变的发生发展有一定相关性,中长期血糖监控指标(GA、HbA1c)比点监测血糖指标(FBG及2hPBG)对DR患者的治疗、预后的预测更有临床意义.
目的 探討糖尿病視網膜病變患者與其血糖控製指標的關繫.方法 選取2型糖尿病患者175例,按眼底變化分為3組.其中糖尿病正常眼底(NDR)組45例,非增生性糖尿病視網膜病變(NPDR)組87例,增生性糖尿病視網膜病變(PDR)組43例.檢測其空腹血糖(FBG)、餐後2h血糖(2hPBG)、糖化血清白蛋白(GA)及糖化血紅蛋白(HbA1c),併相應行眼底檢查.結果 與NDR組相比較,NPDR、PDR組GA、HbA1c升高差異有統計學意義(P<0.05),而在NPDR組與PDR組比較差異無統計學意義(P >0.05);NPDR組中2hPBG水平較NDR組升高差異有統計學意義(P<0.05),而FBG水平DR組與NDR組差異無統計學意義(P>0.05).結論 血糖波動與2型糖尿病視網膜病變的髮生髮展有一定相關性,中長期血糖鑑控指標(GA、HbA1c)比點鑑測血糖指標(FBG及2hPBG)對DR患者的治療、預後的預測更有臨床意義.
목적 탐토당뇨병시망막병변환자여기혈당공제지표적관계.방법 선취2형당뇨병환자175례,안안저변화분위3조.기중당뇨병정상안저(NDR)조45례,비증생성당뇨병시망막병변(NPDR)조87례,증생성당뇨병시망막병변(PDR)조43례.검측기공복혈당(FBG)、찬후2h혈당(2hPBG)、당화혈청백단백(GA)급당화혈홍단백(HbA1c),병상응행안저검사.결과 여NDR조상비교,NPDR、PDR조GA、HbA1c승고차이유통계학의의(P<0.05),이재NPDR조여PDR조비교차이무통계학의의(P >0.05);NPDR조중2hPBG수평교NDR조승고차이유통계학의의(P<0.05),이FBG수평DR조여NDR조차이무통계학의의(P>0.05).결론 혈당파동여2형당뇨병시망막병변적발생발전유일정상관성,중장기혈당감공지표(GA、HbA1c)비점감측혈당지표(FBG급2hPBG)대DR환자적치료、예후적예측경유림상의의.
ObjectiveTo explore the clinical significance between fasting blood glucose (FBG),2h postprandial blood glucose (2hPBG),Glycated Albumin (GA) and Glycosylated hemoglobin (HbAlc) in the occurrence and development of diabetic retinopathy (DR).Methods The subjects were divided into non diabetic retinopathy (NDR) group,non proliferative diabetic retinopathy (NP-DR) group and proliferative diabetic retinopathy (PDR) group.FBG,2hPBG,GA and HbAlc of 175 patients with type 2 diabetes were detected in which DR was diagnosed and staging by fundus examination and fluorescein fundus angiography (FFA).Results There was no difference in FBG among groups (P >0.05) and the 2hPBG of NPDR group was higher than that of NDR and PDR group (P <0.05).The GA and HbAlc of NDR group was lower than those of DR group.Conclusions It suggests that DR and its progression might be closely related to the glucose variability.The GA and HbAlc are desirable markers for controlling diabetic retinopathy.