CAJ | 학술논문

目的探讨LASEK术中使用化学分区浸润法制作上皮瓣的可行性及优缺点.方法对2011年3～12月在焦作五官医院眼科应用LASEK治疗高度近视98例(196只眼)患者,所有病例左眼均使用20％乙醇分区浸润法制作角膜上皮瓣为实验组,右眼均采用常规制瓣方法为对照组.观察术中制瓣情况、术后双眼刺激症状,角膜上皮瓣愈合情况及Haze发生率.结果术中选择上皮瓣完整、边缘整齐者,实验组93只眼,对照组89只眼,差异无统计学意义(u=1.28,P＞0.05);实验组术后刺激症状明显减轻,优于常规对照组(u=8.767,P＜0.01);实验组术后上皮瓣愈合的平整性、透明性好,1级瓣实验组和对照组分别有72只眼和35只眼,两组相比差异有统计学意义(u =5.318,P＜0.01); Haze 0级者实验组和对照组分别有89只眼和78只眼,差异有统计学意义(u=2.245,P＜0.05).结论上皮瓣下角膜原位磨镶术中采用分区浸润法制作角膜上皮瓣,方法简单易于掌握,能有效地减少术后眼部刺激症状及降低Haze发生几率.
목적 탐토LASEK술중사용화학분구침윤법제작상피판적가행성급우결점.방법 대2011년3～12월재초작오관의원안과응용LASEK치료고도근시98례(196지안)환자,소유병례좌안균사용20％을순분구침윤법제작각막상피판위실험조,우안균채용상규제판방법위대조조.관찰술중제판정황、술후쌍안자격증상,각막상피판유합정황급Haze발생솔.결과 술중선택상피판완정、변연정제자,실험조93지안,대조조89지안,차이무통계학의의(u=1.28,P＞0.05);실험조술후자격증상명현감경,우우상규대조조(u=8.767,P＜0.01);실험조술후상피판유합적평정성、투명성호,1급판실험조화대조조분별유72지안화35지안,량조상비차이유통계학의의(u =5.318,P＜0.01); Haze 0급자실험조화대조조분별유89지안화78지안,차이유통계학의의(u=2.245,P＜0.05).결론 상피판하각막원위마양술중채용분구침윤법제작각막상피판,방법간단역우장악,능유효지감소술후안부자격증상급강저Haze발생궤솔.
Objective To determine the effect of using by partition infiltration on corneal epithelial flap during laser assisted subepithelial keratomileusis (LASEK).Methods Ninety-eight patients (196 eyes) with moderate to high myopia were enrolled in the study.The left eye was in experimental group using 20％ alcohol by partition infiltration method and the right eye using standard method as control group.The integrity of corneal epithelial flap during the surgery,postoperative irritation and corneal epithelial flap healing,corneal haze incidence were compared.Results The integrated corneal epithelial flap was in 93 eyes in experimental group and 89 eyes in control group,there was no significant difference in the two groups (u=1.28,P ＞0.05).There was less irritation in experimental group compared with the control group (u=8.767,P ＜0.01).Smoothness and transparency of the corneal epithelial flap in the postoperative were better than the control group (u=5.318,P ＜ 0.01).The haze was less in experimental group.The haze score zero in the two group were in 89 and 78 respectively (u=2.245,P ＜0.05).Conclusions Partition infiltration method in LASEK can reduce the postoperative pain and corneal haze.It is a simple method and easy to learn.