CAJ | 학술논문

目的研究原发性眼后节缺血性疾病与颈动脉狭窄的相关性.方法临床病例对照研究.选择2011年5月至2012年12月在沧州市中心医院就诊的原发性眼后节缺血性疾病患者99例(99只眼),分为三组,A组:32例(32只眼)一过性黑矇,男19例,女13例,平均(64.31±8.15)岁;B组:31例(31只眼)视网膜动脉阻塞,男20例,女11例,平均(63.39±8.06)岁;C组:36例(36只眼)缺血性视神经病变,男19例,女17例,平均(63.50±8.53)岁.对照组:同期门诊30例(30只眼)非眼后节缺血性疾病患者,男12例,女18例,平均(63.03±7.91)岁.对A、B、C3组患者行颈动脉彩色多普勒超声检查,检测其颈动脉狭窄程度、颈动脉斑块部位及类型,并分别与对照组进行比较.结果 A组颈动脉狭窄程度与对照组比较,差异有统计学意义(Z =-3.752,P＜0.01),其中颈动脉中度与重度狭窄分为50％及9.4％,明显高于对照组.B、C组颈动脉狭窄程度与对照组比较,差异均无统计学意义(P＞0.05).B组颈动脉不稳定斑块检出率67.7％ (21/31),与对照组比较,差异有统计学意义(x2=8.887,P =0.003).A、C组颈动脉不稳定斑块检出率与对照组比较,差异均无统计学意义(P＞0.05).四组在颈动脉各部位斑块的分布比例比较经Fisher确切概率法检验,差异无统计学意义(P =0.876).结论一过性黑矇与颈动脉中重度狭窄关系密切.颈动脉不稳定斑块是视网膜动脉阻塞的重要因素.
목적 연구원발성안후절결혈성질병여경동맥협착적상관성.방법 림상병례대조연구.선택2011년5월지2012년12월재창주시중심의원취진적원발성안후절결혈성질병환자99례(99지안),분위삼조,A조:32례(32지안)일과성흑몽,남19례,녀13례,평균(64.31±8.15)세;B조:31례(31지안)시망막동맥조새,남20례,녀11례,평균(63.39±8.06)세;C조:36례(36지안)결혈성시신경병변,남19례,녀17례,평균(63.50±8.53)세.대조조:동기문진30례(30지안)비안후절결혈성질병환자,남12례,녀18례,평균(63.03±7.91)세.대A、B、C3조환자행경동맥채색다보륵초성검사,검측기경동맥협착정도、경동맥반괴부위급류형,병분별여대조조진행비교.결과 A조경동맥협착정도여대조조비교,차이유통계학의의(Z =-3.752,P＜0.01),기중경동맥중도여중도협착분위50％급9.4％,명현고우대조조.B、C조경동맥협착정도여대조조비교,차이균무통계학의의(P＞0.05).B조경동맥불은정반괴검출솔67.7％ (21/31),여대조조비교,차이유통계학의의(x2=8.887,P =0.003).A、C조경동맥불은정반괴검출솔여대조조비교,차이균무통계학의의(P＞0.05).사조재경동맥각부위반괴적분포비례비교경Fisher학절개솔법검험,차이무통계학의의(P =0.876).결론 일과성흑몽여경동맥중중도협착관계밀절.경동맥불은정반괴시시망막동맥조새적중요인소.
Objective To research the correlation of primary posterior ocular ischemic diseases and carotid stenosis.Methods A clinical case-control study.Ninety-nine patients (99 eyes) with primary posterior ocular ischemic diseases were enrolled during May 2011 to December 2012,and divided into three groups:group A,32 patients (32 eyes) with amaurosis fugax.There were 19 males and 13 females whose average age was (64.31±8.15) years old.Group B had 31 patients (31 eyes) with retinal artery occlusion.There were 20 males and 11 females whose average age was (63.39±8.06) years old.Group C had 36 patients (36 eyes) with anterior ischemic optic neuropathy.There were 19 males and 17 females whose average age was (63.50±8.53) years old.Control group had 30 cases (30 eyes) without primary posterior ocular ischemic diseases.There were 12 males and 18 females whose average age was (63.03±7.91) years old.Their carotid arteries were examined with color doppler ultrasound to detect the degree of carotid stenosis,carotid artery plaque area and type.The data were statistically compared respectively with the control group.Results Detection rate of carotid artery moderately and severe stenosis in group A was 50％ (16/32) and 9.4％ (3/32),which was higher compared with the control group.The difference was statistically significant (Z =-3.752,P ＜0.001).There were no statistical differences of detection rate between group B,C and the control group (P ＞0.05).Detection rate of unstable carotid plaques in group B was 67.7％ (21/31),which was higher compared with the control group.The difference was statistically significant (x2 =8.887,P =0.003).There was no significant difference on distribution ratios of each part of the carotid artery in four groups (P =0.876).Conclusions There is close relations between amaurosis fugax and carotid artery moderately and severe stenosis.There is correlation between retinal artery occlusion and unstable carotid plaques.