CAJ | 학술논문

目的观察ICL植入术矫正准分子激光角膜屈光手术后屈光回退的临床疗效.方法临床病例系列研究.选取2012年8月至2013年5月在同济医院眼屈光治疗中心就诊的准分子激光角膜屈光手术后屈光回退的患者8例14只眼,使用ICL植入术进行手术矫正.测量患者手术前后视力、屈光度、前房角(0°和180°方位)、中央前房深度、前房容积、角膜内皮细胞密度、眼压和ICL拱高等指标,并对测量结果进行统计学分析.结果术后6个月时,患者裸眼视力均达到术前最佳矫正视力,屈光度显著降低,差异有统计学意义(P＜0.05);0°方位前房角、180°方位前房角、中央前房深度和前房容积均较术前显著下降,差异有统计学意义(P＜0.05);角膜内皮细胞密度较术前下降,差异有统计学意义(P＜0.05);手术前后眼压差异无统计学意义(P＞0.05);随访期间ICL与晶状体前表面无接触、未引起前房角关闭.结论 ICL植入术可以安全有效地矫正准分子激光角膜屈光手术后的屈光回退,长期疗效有待随访观察.
목적 관찰ICL식입술교정준분자격광각막굴광수술후굴광회퇴적림상료효.방법 림상병례계렬연구.선취2012년8월지2013년5월재동제의원안굴광치료중심취진적준분자격광각막굴광수술후굴광회퇴적환자8례14지안,사용ICL식입술진행수술교정.측량환자수술전후시력、굴광도、전방각(0°화180°방위)、중앙전방심도、전방용적、각막내피세포밀도、안압화ICL공고등지표,병대측량결과진행통계학분석.결과 술후6개월시,환자라안시력균체도술전최가교정시력,굴광도현저강저,차이유통계학의의(P＜0.05);0°방위전방각、180°방위전방각、중앙전방심도화전방용적균교술전현저하강,차이유통계학의의(P＜0.05);각막내피세포밀도교술전하강,차이유통계학의의(P＜0.05);수술전후안압차이무통계학의의(P＞0.05);수방기간ICL여정상체전표면무접촉、미인기전방각관폐.결론 ICL식입술가이안전유효지교정준분자격광각막굴광수술후적굴광회퇴,장기료효유대수방관찰.
Objective To observe the clinical effect of the implantation of implantable collamer lens (ICL) for refractive regression after excimer laser photorefractive keratectomy.Methods From August 2012 to May 2013,14 eyes of 8 patients from Refractive Surgery Center of Tongji Hospital with refractive regression after excimer laser refractive surgery were enrolled and corrected with ICL implantation.Before and 6 months after surgery,visual acuity,refractions,iridocorneal angles (0°,180°),central anterior chamber depth (CACD),anterior chamber volume (ACV),endothelial cell density (ECD) and ICL central vault were examined and statistically analyzed.Results Six months after surgery,the uncorrected visual acuity (UCVA) of 14 eyes achieved preoperative best corrective visual acuity (BCVA),refractions decreased significantly,the difference was statistically significant (P ＜ 0.05); iridocorneal angles (0°,180°),CACD and ACV were lower than that before surgery,the differences were statistically significant (P ＜0.05); the ECD decreased by 10.33％ compared with preoperative ECD,the difference was statistically significant (P ＜0.05); there were no statistical difference between IOPs of pre-and 6 months post-surgery (P ＞0.05); during six months after surgery,ICLs had no contact with lens,and no closure of anterior chamber angle was observed.Conclusions ICL implantation for refractive regression after excimer laser refractive surgery is safe and effective.However,more clinical investigations are needed to clarify its long term outcome.