中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2014年
10期
1223-1226
,共4页
王宗华%白华%马斌超%陈思扬
王宗華%白華%馬斌超%陳思颺
왕종화%백화%마빈초%진사양
早产儿视网膜病变%激光光凝术%极低出生体重%附加病变
早產兒視網膜病變%激光光凝術%極低齣生體重%附加病變
조산인시망막병변%격광광응술%겁저출생체중%부가병변
Retinopathy of prematurity%Laser photocoagulation%Very low birth weight%Plus disease
目的 评价间接检眼镜激光治疗出生体重极低早产儿视网膜病变(retinopathy of rematurity,ROP)的治疗效果及安全性.方法 对2010年1月至2011年12月在北京军区总医院就诊的76例(147只眼)极低出生体重早产儿ROP行间接检眼镜激光治疗,并依据治疗效果分为:病变消退组(133只眼)和病变进展组(14只眼),观察其疗效并比较相关因素.结果 激光治疗后,病变消退总计133只眼,治愈率90.48％ (133/147).激光治疗与出生体重、出生胎龄、治疗时矫正胎龄差异比较无统计学意义(P＞0.05).按ROP分期:病变消退组中Ⅰ区病变36.84％ (49/133),3期为51.13％ (68/133);病变进展组中Ⅰ区病变71.43％ (10/14),3期85.71％ (12/14).提示两组中Ⅰ区病变、3期病变的激光治疗效果较差(x2=6.306,P=0.012; x2=6.109,P=0.013).病变消退组中伴有附加病变87.22％ (116/133),病变进展组伴附加病变者为100％ (14/14).结论 对极低出生体重儿ROP行间接检眼镜激光光凝治疗是安全、有效的,其治疗效果与病变区域、病变程度有关.Ⅰ区和3期病变激光治疗效果差.
目的 評價間接檢眼鏡激光治療齣生體重極低早產兒視網膜病變(retinopathy of rematurity,ROP)的治療效果及安全性.方法 對2010年1月至2011年12月在北京軍區總醫院就診的76例(147隻眼)極低齣生體重早產兒ROP行間接檢眼鏡激光治療,併依據治療效果分為:病變消退組(133隻眼)和病變進展組(14隻眼),觀察其療效併比較相關因素.結果 激光治療後,病變消退總計133隻眼,治愈率90.48％ (133/147).激光治療與齣生體重、齣生胎齡、治療時矯正胎齡差異比較無統計學意義(P＞0.05).按ROP分期:病變消退組中Ⅰ區病變36.84％ (49/133),3期為51.13％ (68/133);病變進展組中Ⅰ區病變71.43％ (10/14),3期85.71％ (12/14).提示兩組中Ⅰ區病變、3期病變的激光治療效果較差(x2=6.306,P=0.012; x2=6.109,P=0.013).病變消退組中伴有附加病變87.22％ (116/133),病變進展組伴附加病變者為100％ (14/14).結論 對極低齣生體重兒ROP行間接檢眼鏡激光光凝治療是安全、有效的,其治療效果與病變區域、病變程度有關.Ⅰ區和3期病變激光治療效果差.
목적 평개간접검안경격광치료출생체중겁저조산인시망막병변(retinopathy of rematurity,ROP)적치료효과급안전성.방법 대2010년1월지2011년12월재북경군구총의원취진적76례(147지안)겁저출생체중조산인ROP행간접검안경격광치료,병의거치료효과분위:병변소퇴조(133지안)화병변진전조(14지안),관찰기료효병비교상관인소.결과 격광치료후,병변소퇴총계133지안,치유솔90.48％ (133/147).격광치료여출생체중、출생태령、치료시교정태령차이비교무통계학의의(P＞0.05).안ROP분기:병변소퇴조중Ⅰ구병변36.84％ (49/133),3기위51.13％ (68/133);병변진전조중Ⅰ구병변71.43％ (10/14),3기85.71％ (12/14).제시량조중Ⅰ구병변、3기병변적격광치료효과교차(x2=6.306,P=0.012; x2=6.109,P=0.013).병변소퇴조중반유부가병변87.22％ (116/133),병변진전조반부가병변자위100％ (14/14).결론 대겁저출생체중인ROP행간접검안경격광광응치료시안전、유효적,기치료효과여병변구역、병변정도유관.Ⅰ구화3기병변격광치료효과차.
Objective To analyze the treatment efficacy of laser photocoagulation for retinopathy of prematurity (ROP) in very low birth weight preterm infants.Methods The clinical records in 76 very low birth weight preterm infants (147 eyes) treated by binocular indirect ophthalmoscopic photocoagulation were retrospectively analyzed.Various risk factors were compared between the progressed infants and the regressed infants.Results Of 133 eyes with ROP were cured by the laser photocoagulation with the curative rate 90.48％.There was no significantly difference in the birth weight,gestational age and the corrected gestational at the time of operation between the progressed infants and the regressed infants (P ＞0.05).In the regressed group,36.84％ (49/133) infants were in zone 1,51.13％ (68/133) infants were stage 3.In the progressed group 71.43％ (10/14) infants were in zone 1 and 85.71％ (12/14) infants were stage 3.ROP in zone 1,at stage 3 and with plus disease might be more dangerous than others (x2=6.306,P =0.012; x2=6.109,P =0.013).In the regressed group 87.22％ (116/133) infants were with plus disease and in the progressed group 100％ infants were with plus disease.Conclusions Binocular indirect ophthalmoscopic photocoagulation is a safe and effective procedure for treatment of ROP in very low birth weight preterm infants.Patients with zone I ROP or at stage 3 always progress quickly and show a poor outcome.
