中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2014年
10期
1100-1103
,共4页
曹珊%侯灵彤%董建新%张克兵
曹珊%侯靈彤%董建新%張剋兵
조산%후령동%동건신%장극병
妊娠结局%人绒毛膜促性腺激素%孕酮%雌二醇%睾酮
妊娠結跼%人絨毛膜促性腺激素%孕酮%雌二醇%睪酮
임신결국%인융모막촉성선격소%잉동%자이순%고동
Pregnancy outcomes%Serum human chorionic gonadotropin%Progesterone%Estradiol%Testosterone
目的 探讨不同妊娠结局者妊娠早期相关激素水平的变化规律.方法 选择早期单胎妊娠妇女314例,随访至孕3个月.采用化学发光分析法检测血清人绒毛膜促性腺激素(β-HCG)、孕酮、雌二醇及睾酮.根据妊娠结局及临床症状进行分组,比较不同妊娠结局者早期妊娠相关激素水平的变化规律.结果 正常妊娠组167例(53.18％);异常妊娠组147例(46.82％),其中先兆流产继续妊娠组102例(69.39％),难免流产组29例(19.73％),胚胎停育组16例(10.88％);正常妊娠组血清雌二醇水平高于先兆流产继续妊娠组、难免流产组及胚胎停育组[(3 104.6±1 507.1)、(2 361.0±1 057.9)、(1 250.0±624.5)、(1465.7±724.4) pmol/L],差异均有统计学意义(P均＜0.05);正常妊娠组血清β-HCG、雌二醇及睾酮水平与孕周均呈正相关(r值分别为0.57、0.62、0.24,P均＜0.05),孕酮水平与孕周无相关性(r=0.15,P=0.06).结论 动态检测孕早期血清β-HCG、孕酮、雌二醇及睾酮可以指导临床医师保胎治疗.
目的 探討不同妊娠結跼者妊娠早期相關激素水平的變化規律.方法 選擇早期單胎妊娠婦女314例,隨訪至孕3箇月.採用化學髮光分析法檢測血清人絨毛膜促性腺激素(β-HCG)、孕酮、雌二醇及睪酮.根據妊娠結跼及臨床癥狀進行分組,比較不同妊娠結跼者早期妊娠相關激素水平的變化規律.結果 正常妊娠組167例(53.18％);異常妊娠組147例(46.82％),其中先兆流產繼續妊娠組102例(69.39％),難免流產組29例(19.73％),胚胎停育組16例(10.88％);正常妊娠組血清雌二醇水平高于先兆流產繼續妊娠組、難免流產組及胚胎停育組[(3 104.6±1 507.1)、(2 361.0±1 057.9)、(1 250.0±624.5)、(1465.7±724.4) pmol/L],差異均有統計學意義(P均＜0.05);正常妊娠組血清β-HCG、雌二醇及睪酮水平與孕週均呈正相關(r值分彆為0.57、0.62、0.24,P均＜0.05),孕酮水平與孕週無相關性(r=0.15,P=0.06).結論 動態檢測孕早期血清β-HCG、孕酮、雌二醇及睪酮可以指導臨床醫師保胎治療.
목적 탐토불동임신결국자임신조기상관격소수평적변화규률.방법 선택조기단태임신부녀314례,수방지잉3개월.채용화학발광분석법검측혈청인융모막촉성선격소(β-HCG)、잉동、자이순급고동.근거임신결국급림상증상진행분조,비교불동임신결국자조기임신상관격소수평적변화규률.결과 정상임신조167례(53.18％);이상임신조147례(46.82％),기중선조유산계속임신조102례(69.39％),난면유산조29례(19.73％),배태정육조16례(10.88％);정상임신조혈청자이순수평고우선조유산계속임신조、난면유산조급배태정육조[(3 104.6±1 507.1)、(2 361.0±1 057.9)、(1 250.0±624.5)、(1465.7±724.4) pmol/L],차이균유통계학의의(P균＜0.05);정상임신조혈청β-HCG、자이순급고동수평여잉주균정정상관(r치분별위0.57、0.62、0.24,P균＜0.05),잉동수평여잉주무상관성(r=0.15,P=0.06).결론 동태검측잉조기혈청β-HCG、잉동、자이순급고동가이지도림상의사보태치료.
Objective To explore the rules of early pregnancy related hormone changes in different pregnancy outcomes.Methods Three hundred and fourteen women at early pregnancy women were selected as our subjects.And they were followed up until 3 months of gestation.chemiluminescence analysis was used to test serum human chorionic gonadotropin (β-HCG),progesterone,estradiol and testosterone levels all pregnant women.According to the pregnancy outcome,clinical symptom and body mass index,all subjects were divided into normal and abnormal group.Results Among 314 cases of early pregnancy women,the normal pregnancy group was 53.18％ (167/314) and the abnormal pregnancy were 46.82％ (147/314).While in abnormal pregnancy group,women with the threatened abortion and continues pregnancy were 102 cases(69.39％),with inevitable abortion group were 29 cases (19.73％),and with embryos diapauses were 16 cases (10.88％).Serum estradiol level of cases in normal pregnancy group was (3104.6 ± 1507.1) pmol/L,higher than that in threatened abortion and continues pregnancy,threatened abortion group and inevitable abortion group((2 361.0 ±1 057.9) pmol/L,(1 250.0 ±624.5) pmol/L,(1 465.7 ±724.4) pmol/L)),and the differences were statistically significant(P ＜ 0.05).In normal pregnancy group,the level of serum β-HCG,estradiol and testosterone were positively correlated with gestational age (r =0.57,0.62 and 0.24 ; P ＜ 0.05).However,progesterone levels had no correlation with gestational age (r =0.15,P =0.06).Conclusion Dynamic detection of early pregnancy can guide clinicians to colytic therapy.
