中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2014年
6期
511-513
,共3页
卢妍妍%阎琳%蒋珊%李幼辉
盧妍妍%閻琳%蔣珊%李幼輝
로연연%염림%장산%리유휘
抑郁症%躯体症状%血清皮质醇%述情障碍
抑鬱癥%軀體癥狀%血清皮質醇%述情障礙
억욱증%구체증상%혈청피질순%술정장애
Depression%Somatic symptoms%Cortisol%Alexithymia
目的 探讨伴躯体症状的抑郁症患者血清皮质醇水平与述情障碍程度的相关性.方法 采用放射免疫法测定30例伴躯体症状的抑郁症患者(躯体组)及30例不伴躯体症状的抑郁症患者(不伴组)晨起血清皮质醇水平,使用述情障碍量表(TAS-20)评定两组患者述情障碍.结果 (1)躯体组血清皮质醇水平显著高于不伴组[(533.88± 144.10) μmol/L vs (458.27±82.87) μmol/L,P＜0.01],差异有统计学意义.(2)躯体组述情障碍总分及识别情感障碍、描述情感障碍因子分高于不伴组[(67.13±6.96)分vs(62.03±7.14)分,(24.50±3.78)分vs (21.63±3.63)分,(15.30±2.69)分vs(13.57±2.03)分,均P＜0.01],差异有统计学意义.(3)躯体组血清皮质醇水平与述情障碍总分正相关(r=0.596,P＜0.01),与识别情感障碍、描述情感障碍、外向性思维因子分正相关(r=0.391,0.435,0.452,均P＜0.05).(4)不伴组血清皮质醇水平与述情障碍总分正相关(r=0.418,P＜0.05),与外向性思维因子分正相关(r=0.489,P＜0.01).结论 伴躯体症状较不伴躯体症状的抑郁症患者存在较重的述情障碍,具体体现在识别情绪障碍、描述情绪障碍.述情障碍的严重程度与血清皮质醇水平存在正相关关系.
目的 探討伴軀體癥狀的抑鬱癥患者血清皮質醇水平與述情障礙程度的相關性.方法 採用放射免疫法測定30例伴軀體癥狀的抑鬱癥患者(軀體組)及30例不伴軀體癥狀的抑鬱癥患者(不伴組)晨起血清皮質醇水平,使用述情障礙量錶(TAS-20)評定兩組患者述情障礙.結果 (1)軀體組血清皮質醇水平顯著高于不伴組[(533.88± 144.10) μmol/L vs (458.27±82.87) μmol/L,P＜0.01],差異有統計學意義.(2)軀體組述情障礙總分及識彆情感障礙、描述情感障礙因子分高于不伴組[(67.13±6.96)分vs(62.03±7.14)分,(24.50±3.78)分vs (21.63±3.63)分,(15.30±2.69)分vs(13.57±2.03)分,均P＜0.01],差異有統計學意義.(3)軀體組血清皮質醇水平與述情障礙總分正相關(r=0.596,P＜0.01),與識彆情感障礙、描述情感障礙、外嚮性思維因子分正相關(r=0.391,0.435,0.452,均P＜0.05).(4)不伴組血清皮質醇水平與述情障礙總分正相關(r=0.418,P＜0.05),與外嚮性思維因子分正相關(r=0.489,P＜0.01).結論 伴軀體癥狀較不伴軀體癥狀的抑鬱癥患者存在較重的述情障礙,具體體現在識彆情緒障礙、描述情緒障礙.述情障礙的嚴重程度與血清皮質醇水平存在正相關關繫.
목적 탐토반구체증상적억욱증환자혈청피질순수평여술정장애정도적상관성.방법 채용방사면역법측정30례반구체증상적억욱증환자(구체조)급30례불반구체증상적억욱증환자(불반조)신기혈청피질순수평,사용술정장애량표(TAS-20)평정량조환자술정장애.결과 (1)구체조혈청피질순수평현저고우불반조[(533.88± 144.10) μmol/L vs (458.27±82.87) μmol/L,P＜0.01],차이유통계학의의.(2)구체조술정장애총분급식별정감장애、묘술정감장애인자분고우불반조[(67.13±6.96)분vs(62.03±7.14)분,(24.50±3.78)분vs (21.63±3.63)분,(15.30±2.69)분vs(13.57±2.03)분,균P＜0.01],차이유통계학의의.(3)구체조혈청피질순수평여술정장애총분정상관(r=0.596,P＜0.01),여식별정감장애、묘술정감장애、외향성사유인자분정상관(r=0.391,0.435,0.452,균P＜0.05).(4)불반조혈청피질순수평여술정장애총분정상관(r=0.418,P＜0.05),여외향성사유인자분정상관(r=0.489,P＜0.01).결론 반구체증상교불반구체증상적억욱증환자존재교중적술정장애,구체체현재식별정서장애、묘술정서장애.술정장애적엄중정도여혈청피질순수평존재정상관관계.
Objective To investigate the correlation between the level of serum cortisol and alexithymia in depressive patients with somatic symptoms.Methods The morning level of serum cortisol was measured with radioimmunoassay in 30 depressive patients with somatic symptoms (somatization group) and 30 depressive patients without somatic symptoms (non-somatization group).The severity of alexithymia was evaluated with Toronto alexithymia Scale(TAS-20).Results (1) The level of serum cortisol in somatization group was significantly higher than that in non-somatization group((533.88±144.10) μmol/L vs (458.27±82.87) μmol/L,P＜0.01).(2) The total TAS score and the factor score of "Difficulty in identifying feelings" and "Difficulty in describing feelings" in somatization group were obviously higher than those in non-somatization group,respectively ((67.13 ± 6.96) vs (62.03±7.14),(24.50±3.78) vs (21.63±3.63),(15.30±2.69) vs (13.57±2.03),all P＜0.01).(3) The level of serum cortisol in somatization group was positively correlated with the total score of alexithymia (r=0.596,P＜0.01) and the factor score of "Difficulty in identifying feelings"," Difficulty in describing feelings"," externally oriented thinking",respectively (r=0.391,0.435,0.452,all P＜0.05).(4) The level of serum cortisol in non-somatization group was positively related to the total TAS score (r=0.418,P＜0.05) and the factor score of "externally oriented thinking"(r=0.489,P＜0.01).Conclusions Compared with depressive patients without somatic symptoms,depressive patients with somatic symptoms had more severe alexithymia,especially in "Difficulty in identifying feelings" and "Difficulty in describing feelings".The severity of alexithymia was positively correlated with the level of serum cortisol.
