中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2014年
6期
519-521
,共3页
祝海洲%曹先德%陈晔%孟琳
祝海洲%曹先德%陳曄%孟琳
축해주%조선덕%진엽%맹림
焦虑%青年男性%血清性激素%勃起功能障碍
焦慮%青年男性%血清性激素%勃起功能障礙
초필%청년남성%혈청성격소%발기공능장애
Anxiety%Young men%Serum sex hormone%Erectile dysfunction
目的 探讨焦虑对青年男性性激素水平及勃起功能障碍的影响及相关性.方法 通过问卷式调查,根据焦虑自评量表(SAS)评分,将120名青年男性分为正常组(26例)、轻度焦虑症状组(36例)、中度焦虑症状组(32例)、重度焦虑症状组(26例).采用免疫化学发光法检测血清性激素:促卵泡激素(FSH)、黄体生成素(LH)、催乳素(PRL)、睾酮(T)、雌二醇(E2)浓度.使用国际勃起功能指数评分(IIEF-5).结果 焦虑患者血清FSH、LH、PRL、E2有升高趋势,与正常组比较,差异无统计学意义(F=0.28,P=0.08;F=2.91,P=0.06; F=0.90,P=0.44;F=0.80,P=0.15);中度焦虑症状、重度焦虑症状组血清T、IIEF-5评分明显降低,与正常组比较差异有统计学意义(P=0.00);焦虑越严重,勃起能障碍发生率越高(x2=72.423,P=0.00),勃起功能障碍与焦虑程度呈正相关(r=0.637,P=0.00),睾酮在焦虑评分对IIEF-5评分的关系中产生了部分中介作用.结论 焦虑可引起性激素紊乱,降低睾酮水平,并可致勃起功能障碍.
目的 探討焦慮對青年男性性激素水平及勃起功能障礙的影響及相關性.方法 通過問捲式調查,根據焦慮自評量錶(SAS)評分,將120名青年男性分為正常組(26例)、輕度焦慮癥狀組(36例)、中度焦慮癥狀組(32例)、重度焦慮癥狀組(26例).採用免疫化學髮光法檢測血清性激素:促卵泡激素(FSH)、黃體生成素(LH)、催乳素(PRL)、睪酮(T)、雌二醇(E2)濃度.使用國際勃起功能指數評分(IIEF-5).結果 焦慮患者血清FSH、LH、PRL、E2有升高趨勢,與正常組比較,差異無統計學意義(F=0.28,P=0.08;F=2.91,P=0.06; F=0.90,P=0.44;F=0.80,P=0.15);中度焦慮癥狀、重度焦慮癥狀組血清T、IIEF-5評分明顯降低,與正常組比較差異有統計學意義(P=0.00);焦慮越嚴重,勃起能障礙髮生率越高(x2=72.423,P=0.00),勃起功能障礙與焦慮程度呈正相關(r=0.637,P=0.00),睪酮在焦慮評分對IIEF-5評分的關繫中產生瞭部分中介作用.結論 焦慮可引起性激素紊亂,降低睪酮水平,併可緻勃起功能障礙.
목적 탐토초필대청년남성성격소수평급발기공능장애적영향급상관성.방법 통과문권식조사,근거초필자평량표(SAS)평분,장120명청년남성분위정상조(26례)、경도초필증상조(36례)、중도초필증상조(32례)、중도초필증상조(26례).채용면역화학발광법검측혈청성격소:촉란포격소(FSH)、황체생성소(LH)、최유소(PRL)、고동(T)、자이순(E2)농도.사용국제발기공능지수평분(IIEF-5).결과 초필환자혈청FSH、LH、PRL、E2유승고추세,여정상조비교,차이무통계학의의(F=0.28,P=0.08;F=2.91,P=0.06; F=0.90,P=0.44;F=0.80,P=0.15);중도초필증상、중도초필증상조혈청T、IIEF-5평분명현강저,여정상조비교차이유통계학의의(P=0.00);초필월엄중,발기능장애발생솔월고(x2=72.423,P=0.00),발기공능장애여초필정도정정상관(r=0.637,P=0.00),고동재초필평분대IIEF-5평분적관계중산생료부분중개작용.결론 초필가인기성격소문란,강저고동수평,병가치발기공능장애.
Objective To explore the effects of anxiety-like behaviors on the levels of sex hormones and severity of erectile dysfunction(ED) in young men.Methods A total of 120 young men with ED,between the ages of 23 and 35 years,were prospectively studied,and all of them were the outpatients from the Affiliated Hospital of Jining Medical University from January 2012 to October 2013.Self-Rating Anxiety Scale (SAS) was used.According to the scores of SAS,the patients were divided into four groups.26 were rated by SAS as in the normal,36 in the mild,32 in the moderate and 26 in the severe state of anxiety.The levels of serum sex hormone (FSH,LH,PRL,T,E2) were detected by immunochemiluminometric assays.ED was assessed using the IIEF-5.Further,the responses were divided into three diagnosing groups on the basis of cutoff scores for IIEF-5.The relationship between the SAS scores of measuring anxiety,serum sex hormone levels,and the indicators for ED,Spearman rank correlations were carried out.Results Comparing with the normal control group,the levels of serum sex hormones (FSH,LH,PRL,E2) increased in other groups,but there were no significant differences (F=0.28,P=0.08 ; F=2.91,P=0.06; F=0.90,P=0.44; F=0.80,P=0.15).The levels of serum testosterone and the scores of IIEF-5 in the moderate and severe anxiety group decreased.The more severe symptoms of anxiety,the more likely that the ED would occur(x2=72.423,P=0.00),and ED was significantly positively correlated with anxiety(r=0.637,P=0.00).Testosterone played the partial intermediary role on the relationship between anxiety score and the IIEF-5 score.Conclusion Anxiety may contribute to ED through disturbing the sex hormone and lowering the level of serum testosterone.
