中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2014年
7期
625-626
,共2页
动态脉压%脉压指数%认知功能
動態脈壓%脈壓指數%認知功能
동태맥압%맥압지수%인지공능
Ambulatory pulse pressure%Pulse pressure index%Cognitive function
目的 探讨动态脉压(PP)、脉压指数(PPI)与认知功能损害(VCI)程度的关系.方法 将60名重度、中度、轻度认知功能障碍患者作为研究对象,40名健康人作为对照组,所有患者进行动态血压的监测.结果 重度VCI组的PP、PPI显著高于中度、轻度VCI组及对照组[PP(mmHg):(59.10±11.82、54.94±10.86、50.28±8.33、45.54±9.22,P＜0.05),PPI:(0.61±0.08、0.53±0.06、0.44±0.05、0.37±0.03,P＜0.05)],其MMSE评分显著低于中度、轻度及对照组[(15.56±2.64)分、(19.32±3.32)分、(22.62±3.11)分、(26.45±2.94)分,P＜0.05];中度VCI组PP、PPI显著高于对照组(P＜0.05),MMSE评分显著低于轻度VCI及对照组(P＜0.05).直线相关分析显示PP,PPI与MMSE评分呈明显负相关.结论 动态脉压、脉压指数的增加与认知功能的损害有关.
目的 探討動態脈壓(PP)、脈壓指數(PPI)與認知功能損害(VCI)程度的關繫.方法 將60名重度、中度、輕度認知功能障礙患者作為研究對象,40名健康人作為對照組,所有患者進行動態血壓的鑑測.結果 重度VCI組的PP、PPI顯著高于中度、輕度VCI組及對照組[PP(mmHg):(59.10±11.82、54.94±10.86、50.28±8.33、45.54±9.22,P＜0.05),PPI:(0.61±0.08、0.53±0.06、0.44±0.05、0.37±0.03,P＜0.05)],其MMSE評分顯著低于中度、輕度及對照組[(15.56±2.64)分、(19.32±3.32)分、(22.62±3.11)分、(26.45±2.94)分,P＜0.05];中度VCI組PP、PPI顯著高于對照組(P＜0.05),MMSE評分顯著低于輕度VCI及對照組(P＜0.05).直線相關分析顯示PP,PPI與MMSE評分呈明顯負相關.結論 動態脈壓、脈壓指數的增加與認知功能的損害有關.
목적 탐토동태맥압(PP)、맥압지수(PPI)여인지공능손해(VCI)정도적관계.방법 장60명중도、중도、경도인지공능장애환자작위연구대상,40명건강인작위대조조,소유환자진행동태혈압적감측.결과 중도VCI조적PP、PPI현저고우중도、경도VCI조급대조조[PP(mmHg):(59.10±11.82、54.94±10.86、50.28±8.33、45.54±9.22,P＜0.05),PPI:(0.61±0.08、0.53±0.06、0.44±0.05、0.37±0.03,P＜0.05)],기MMSE평분현저저우중도、경도급대조조[(15.56±2.64)분、(19.32±3.32)분、(22.62±3.11)분、(26.45±2.94)분,P＜0.05];중도VCI조PP、PPI현저고우대조조(P＜0.05),MMSE평분현저저우경도VCI급대조조(P＜0.05).직선상관분석현시PP,PPI여MMSE평분정명현부상관.결론 동태맥압、맥압지수적증가여인지공능적손해유관.
Objective To assess the relationship between ambulatory pulse pressure (PP),pulse pressure indices (PPI) and the severity of cognitive function.Methods Sixty patients with severe,moderate,mild vascular cognitive impairment(VCI) as the research object,and forty healthy people as control group.All of the patients of ambulatory blood pressure were monitored.Results Severe VCI group of PP and PPI was significantly higher than moderate,mild VCI group and the control group (PP (mmHg):(59.10 ± 11.82,54.94 ± 10.86,50.28 ±8.33,45.54±9.22,P＜0.05),PPI:(0.61±0.08,0.53±0.06,0.44±0.05,0.37±0.03,P＜0.05),and the MMSE score was significantly lower than moderate,mild,and the control group(15.56±2.64,19.32±3.32,22.62±3.11,26.45±2.94,P＜0.05).Moderate VCI group of PP and PPI was significantly higher than the control group(P＜0.05).MMSE score was significantly lower than mild VCI and the control group(P＜0.05).Linear correlation analysis showed that PP and PPI was significantly negative related to MMSE score.Conclusion The increase of dynamic pulse pressure,pulse pressure index is associated with the damage of cognitive function.
