CAJ | 학술논문

目的探讨失眠症患者心率变异性及其执行功能的状况以及心率变异性与执行功能的关系.方法对失眠症患者165例与正常对照92例,采用匹兹堡睡眠质量指数(PSQI)进行失眠状况的筛查,威斯康星卡片分类测验(WCST)进行执行功能评估,生理相干与自主平衡系统(SPCS)采集心率变异性(HRV)数据.结果 HRV中SDNN、RMSSD、TP、LF、HF指标,患者组显著高于对照组(t=2.712,2.726,2.427,2.542,2.338,P＜0.05或P＜0.01);WCST中完成分类数、概念化水平百分数,患者组显著低于对照组(t=-2.368,-2.165,均P＜0.05);持续性错误数、持续性错误百分数、持续性应答数显著高于对照组(t=2.712,2.991,2.690,均P＜0.01).HRV中TP、LF、HF、LF/HF与WCST中错误应答数、持续性错误数、持续性错误百分数、持续性应答数呈显著负相关(r=-0.171 ～-0.245,P＜0.05或P＜0.01),与概念化水平百分数呈显著正相关(r=0.198～ 0.227,P＜0.05或P＜0.01).结论本研究发现失眠不仅造成了个体植物神经的紊乱,同时对其大脑前额叶执行功能形成了损害;失眠症患者HRV与执行功能之间存在密切的相关.
목적 탐토실면증환자심솔변이성급기집행공능적상황이급심솔변이성여집행공능적관계.방법 대실면증환자165례여정상대조92례,채용필자보수면질량지수(PSQI)진행실면상황적사사,위사강성잡편분류측험(WCST)진행집행공능평고,생리상간여자주평형계통(SPCS)채집심솔변이성(HRV)수거.결과 HRV중SDNN、RMSSD、TP、LF、HF지표,환자조현저고우대조조(t=2.712,2.726,2.427,2.542,2.338,P＜0.05혹P＜0.01);WCST중완성분류수、개념화수평백분수,환자조현저저우대조조(t=-2.368,-2.165,균P＜0.05);지속성착오수、지속성착오백분수、지속성응답수현저고우대조조(t=2.712,2.991,2.690,균P＜0.01).HRV중TP、LF、HF、LF/HF여WCST중착오응답수、지속성착오수、지속성착오백분수、지속성응답수정현저부상관(r=-0.171 ～-0.245,P＜0.05혹P＜0.01),여개념화수평백분수정현저정상관(r=0.198～ 0.227,P＜0.05혹P＜0.01).결론 본연구발현실면불부조성료개체식물신경적문란,동시대기대뇌전액협집행공능형성료손해;실면증환자HRV여집행공능지간존재밀절적상관.
Objective To investigate status about the heart rate variability and executive function in patients with insomnia.Methods The study involves 165 cases of patients with insomnia and 92 cases normal.The Pittsburgh Sleep Quality Index (PSQI) screening for insomnia,Wisconsin Card Sorting Test (WCST) for the assessment of executive function and Self-generate Physiological Coherence System (SPCS) were used to collect the data of heart rate variability (HRV).Results The SDNN,RMSSD,TP,LF,HF of HRV of the insomnia group were significantly higher than these factors of control group (t=2.712,2.726,2.427,2.542,2.338,P＜0.05 or P＜ 0.01).In the WCST,number of completed categories,conceptualization percentage of the group of patients with insomnia were significantly lower than the control group (t=-2.368,-2.165,all P＜0.05),persistent errors,persistent error percentages,continuous number of responses of patients' group were significantly higher than the control group (t=2.712,2.991,2.690,all P＜0.01).TP,LF,HF,LF/HF of HRV and the number of error responses,persistent errors,persistent error percentages,continuous number of responses of WCST had significant negative correlations (r=-0.171--0.245,P＜0.05 or P＜0.01),while the conceptualization percentage were significantly positively correlated (r=0.198-0.227,P＜0.05 or P＜0.01).Conclusion The results show that insomnia not only cause individual autonomic disorders,but damage the executive function of prefrontal.HRV and executive function in patients with insomnia have close relationships.