CAJ | 학술논문

目的观察舍曲林联合脑功能治疗仪对抑郁发作的疗效.方法将80例不伴严重躯体疾病的抑郁发作患者,按照入院先后顺序分为舍曲林联合脑功能治疗组(40例,A组)和单纯服用舍曲林组(40例,B组),两组均给予服用舍曲林100 mg/d,疗程8周.观察治疗前及治疗1,2,4,6,8周末24项汉密尔顿抑郁量表(HAMD-24)、20项抑郁自评量表(SDS-20)的评分变化情况.结果治疗前两组之间HAMD、SDS的评分均差异无统计学意义(P＞0.05),治疗后均差异有统计学意义(P＜0.05).治疗8周末A组下降幅度明显,B组下降趋势平稳.两组的HAMD临床评分有效率分别为87.2％、76.3％,SDS临床评分有效率分别为89.7％、78.9％,A组疗效明显优于B组(P＜0.05).结论舍曲林联合脑功能治疗能缩短起效时间,提高舍曲林的疗效.
목적 관찰사곡림연합뇌공능치료의대억욱발작적료효.방법 장80례불반엄중구체질병적억욱발작환자,안조입원선후순서분위사곡림연합뇌공능치료조(40례,A조)화단순복용사곡림조(40례,B조),량조균급여복용사곡림100 mg/d,료정8주.관찰치료전급치료1,2,4,6,8주말24항한밀이돈억욱량표(HAMD-24)、20항억욱자평량표(SDS-20)적평분변화정황.결과 치료전량조지간HAMD、SDS적평분균차이무통계학의의(P＞0.05),치료후균차이유통계학의의(P＜0.05).치료8주말A조하강폭도명현,B조하강추세평은.량조적HAMD림상평분유효솔분별위87.2％、76.3％,SDS림상평분유효솔분별위89.7％、78.9％,A조료효명현우우B조(P＜0.05).결론 사곡림연합뇌공능치료능축단기효시간,제고사곡림적료효.
Objective To observe the therapeutic effect of sertraline combined with brain function treatment instrument for depressive episodes.Methods According to sequence of hospitalization,80 patients with depression without severe physical disease randomly divided into sertraline with brain function treatment group (40 cases,group A) and only take sertraline group (40 cases,group B),and two groups were given Sertraline 100 mg/day for 8 weeks.24 Hamilton Depression Scale (HAMD-24) and 20 Self-rating Depression Scale (SDS-20) were assessed before and after 1,2,4,6,8 weekend treatment.Results The scores of HAMD-24 and SDS-20 were not significant difference between the two groups before treatment(P＞0.05),but there were statistically significant after treatment (P＜0.05).They were significantly decreased after 8 weeks treatment in group A and were decreased slightly in group B with HAMD-24 and SDS-20.Clinical efficiencies of HAMD of the two groups were 87.2 ％,76.3 ％,respectively,and those of SDS were 89.7 ％,78.9 ％,respectively.Clinical efficacy in group A was significantly better than that in group B (P＜0.05).Conclusion Sertraline with brain function treatment instrument can shorten the onset time and improve its effect.