CAJ | 학술논문

目的探讨不同症状维度的强迫症患者生活质量的差异性.方法收集54例门诊及住院强迫症患者组成研究组,54例健康人组成对照组;采用健康状况问卷(SF-36)调查生活质量.对形究组使用耶鲁布朗强迫症状清单(YBOCS-SC)评估后进行分析.结果研究组的SF-36得分除生理机能外,其他各项评分均低于对照组,尤其精神健康领域的项目表现突出,如精神健康(t=12.474,P＜0.01)、情感职能(t=9.407,P＜0.01)、社会功能(t=8.862,P＜0.01)、精力(t=8.057,P＜0.01).经因子分析将研究组症状降维后得到四个维度:①简称对称/排序,贡献率21.60％;②简称污染/清洗维度,贡献率16.37％;③简称攻击/宗教维度,贡献率12.34％;④简称性/检查维度,贡献率10.90％.方差分析显示不同症状维度的患者在生理职能(F=5.199,P=0.004)、躯体疼痛(F=3.169,P=0.034)、情感职能(F=9.350,P=0.000)、精神健康(F=4.854,P=0.005)等项目上的差异性具有统计学意义;经LSD多重检验发现,差异主要表现在前三组与④组之间.结论强迫症患者的精神健康受损严重;强迫症的症状维度具有稳定性;不同症状维度患者的生活质量受损差异性显示强迫症症状可能具有异质性.
목적 탐토불동증상유도적강박증환자생활질량적차이성.방법 수집54례문진급주원강박증환자조성연구조,54례건강인조성대조조;채용건강상황문권(SF-36)조사생활질량.대형구조사용야로포랑강박증상청단(YBOCS-SC)평고후진행분석.결과 연구조적SF-36득분제생리궤능외,기타각항평분균저우대조조,우기정신건강영역적항목표현돌출,여정신건강(t=12.474,P＜0.01)、정감직능(t=9.407,P＜0.01)、사회공능(t=8.862,P＜0.01)、정력(t=8.057,P＜0.01).경인자분석장연구조증상강유후득도사개유도:①간칭대칭/배서,공헌솔21.60％;②간칭오염/청세유도,공헌솔16.37％;③간칭공격/종교유도,공헌솔12.34％;④간칭성/검사유도,공헌솔10.90％.방차분석현시불동증상유도적환자재생리직능(F=5.199,P=0.004)、구체동통(F=3.169,P=0.034)、정감직능(F=9.350,P=0.000)、정신건강(F=4.854,P=0.005)등항목상적차이성구유통계학의의;경LSD다중검험발현,차이주요표현재전삼조여④조지간.결론 강박증환자적정신건강수손엄중;강박증적증상유도구유은정성;불동증상유도환자적생활질량수손차이성현시강박증증상가능구유이질성.
Objective To investigate the difference of quality of life in patients with different symptom dimensions of obsessive-compulsive disorder(OCD).Methods Collected 54 cases of outpatient and the first inpatient with OCD to be the research group and 54 normal persons were the control group.The quality of life was assessed with SF-36,and compared the scores.An analysis was performed on the major categories of the YBOCS-SC to derive symptom dimension scores.Results Compared to the control group,patients with OCD showed significant impairment in seven domains of quality of life,especially in the mental health(t=12.474,P＜0.01),the roleemotional(t=9.407,P＜0.01),the social functioning(t=8.862,P＜0.01) and the vitality(t=8.057,P＜0.01).The patients with distinct symptom dimensions of ①symmetry/order,contribution rate 21.60％ ; ②contaminate/clean,contribution rate 16.37％; ③ aggression/religion,contribution rate 12.34％; ④ sex/check,contribution rate 10.90％.They showed different severity of the impairments in four domains of quality of life,the role-physical(F=5.199,P=0.004),the bodily pain (F=3.169,P=0.034),the role-emotional (F=9.350,P=0.000),the mental health(F=4.854,P=0.005).The differences mainly found between the ①②③group and the ④group by LSD multiple testing.Conclusion The mental health is severely damaged with OCD patients.There is stability with the structure of the symptom dimensions of OCD.And it maybe showed the heterogeneity of the symptoms for the significant difference of impairments of quality of life in patients with OCD.