CAJ | 학술논문

目的分析AD患者在语义加工过程中由形到音、以及由音到义这两个步骤损害的差异及其特征.方法假词测验内容包括2部分:假-真词、假-假词,每组各10个.20个词随机呈现,分别记录每个词阅读正确数(代表形→音)与判断正确数(代表音→义),正确得1分,错误或不知道得0分.每组总分为20分.结果 41例轻度AD和135名正常对照组被试在年龄、性别和教育程度上差异无统计学意义,MMSE总分分别为(21.06±2.86)分和(28.08± 1.52)分.正常老人组和轻度AD组,假-真词、假-假词“形→音”阅读正确数与“音→义”判断正确数无显著相关性(P＞0.05).正常老人和轻度AD组的假词测验表现比较:在“形→音”阶段,正常老人和轻度AD组的假词阅读差异无统计学意义(P＞0.05),在“音→义”阶段,假-真词判断正确数在两组间差异有统计学意义(P＜0.01),而假-假词在两组间差异无统计学意义(P＞0.05).结论轻度AD患者存在“音→义”联络通路的损害.
목적 분석AD환자재어의가공과정중유형도음、이급유음도의저량개보취손해적차이급기특정.방법 가사측험내용포괄2부분:가-진사、가-가사,매조각10개.20개사수궤정현,분별기록매개사열독정학수(대표형→음)여판단정학수(대표음→의),정학득1분,착오혹불지도득0분.매조총분위20분.결과 41례경도AD화135명정상대조조피시재년령、성별화교육정도상차이무통계학의의,MMSE총분분별위(21.06±2.86)분화(28.08± 1.52)분.정상노인조화경도AD조,가-진사、가-가사“형→음”열독정학수여“음→의”판단정학수무현저상관성(P＞0.05).정상노인화경도AD조적가사측험표현비교:재“형→음”계단,정상노인화경도AD조적가사열독차이무통계학의의(P＞0.05),재“음→의”계단,가-진사판단정학수재량조간차이유통계학의의(P＜0.01),이가-가사재량조간차이무통계학의의(P＞0.05).결론 경도AD환자존재“음→의”련락통로적손해.
Objective To analyze the language function impairment differences between the two steps from the form to sound processing and from the sound to meaning processing for pseudo-words reading in Alzheimer' s disease (AD).Methods The pseudo-words reading test consists two parts:pseudo-true words and pseudopseudo words.Each part had 10 words.All of the 20 words were presented randomly.Correct reading presents the processing of from form to sound,and correct judging presents the processing of from sound to meaning.Each correct respond get 1 score,otherwise get 0.Each part had a total score of 20.Results The pseudo-words reading test was performed to 41 mild AD participants with Mini-mental State Examination (MMSE) average scores of (21.06 ±2.86),and 135 normal controls with MMSE average scores of (28.08± 1.52).The two groups were matched in age,gender and education.For all of the mild AD group and normal control group,there was no significant difference between reading score and judging score in either pseudo-true words or pseudo-pseudo words (P＞0.05).Comparing with mild AD group and normal control group,there was no significant difference in reading score in either pseudo-true words or pseudo-pseudo words (P＞0.05).For judging score,there was significant difference in pseudotrue words (P＜0.01) but not in pseudo-pseudo words (P＞0.05).Conclusion Understanding real syllable is impaired in patients with mild AD.