中国医师杂志
中國醫師雜誌
중국의사잡지
JOURNAL OF CHINESE PHYSICIAN
2013年
4期
445-448
,共4页
内窥镜检查%黏膜/外科学%消化系统肿瘤/外科学
內窺鏡檢查%黏膜/外科學%消化繫統腫瘤/外科學
내규경검사%점막/외과학%소화계통종류/외과학
Endoscopy%Mucous membrane/surgery%Digestive system neoplasms/surgery
目的 观察比较消化道早期癌的内镜黏膜下剥离和外科手术治疗疗效.方法 60例消化道早期癌患者分成两组,33例给予内镜黏膜下剥离(endoscopic submucosal dissection,ESD)治疗(ESD组),27例给予外科手术治疗(外科组).治疗过程中观察两种方法的治疗成功率、生存时间、复发及转移情况、营养状况、不良反应及并发症的发生率、住院时间及治疗费用.结果 ESD组和外科组的治疗成功率、生存时间、复发及转移情况比较差异无统计学意义(P＞0.05);ESD组营养状况达正常值率90.9％(30/33),外科组营养状况达正常值率66.7％(18/27);ESD组不良反应及并发症发生率为9.09％(3/33),外科组不良反应及并发症发生率为59.2％(16/27).两组营养状况达正常值率、不良反应及并发症发生率差异有统计学意义(P＜ 0.05,P＜0.01).ESD组住院时间(14.81±3.27)d,治疗费用(10562.01±3060.08)元;外科组住院时间(19.22 ±6.91)d,治疗费用(16587.87±5664.50)元.外科组住院时间较ESD组长,治疗费用较ESD组贵.结论 消化道早期癌ESD治疗,与外科手术的疗效相当,术后不良反应较外科手术发生率低,住院时间短,治疗费用相对较低,特别是能保留患者消化道的完整性,生活质量显著提高.
目的 觀察比較消化道早期癌的內鏡黏膜下剝離和外科手術治療療效.方法 60例消化道早期癌患者分成兩組,33例給予內鏡黏膜下剝離(endoscopic submucosal dissection,ESD)治療(ESD組),27例給予外科手術治療(外科組).治療過程中觀察兩種方法的治療成功率、生存時間、複髮及轉移情況、營養狀況、不良反應及併髮癥的髮生率、住院時間及治療費用.結果 ESD組和外科組的治療成功率、生存時間、複髮及轉移情況比較差異無統計學意義(P＞0.05);ESD組營養狀況達正常值率90.9％(30/33),外科組營養狀況達正常值率66.7％(18/27);ESD組不良反應及併髮癥髮生率為9.09％(3/33),外科組不良反應及併髮癥髮生率為59.2％(16/27).兩組營養狀況達正常值率、不良反應及併髮癥髮生率差異有統計學意義(P＜ 0.05,P＜0.01).ESD組住院時間(14.81±3.27)d,治療費用(10562.01±3060.08)元;外科組住院時間(19.22 ±6.91)d,治療費用(16587.87±5664.50)元.外科組住院時間較ESD組長,治療費用較ESD組貴.結論 消化道早期癌ESD治療,與外科手術的療效相噹,術後不良反應較外科手術髮生率低,住院時間短,治療費用相對較低,特彆是能保留患者消化道的完整性,生活質量顯著提高.
목적 관찰비교소화도조기암적내경점막하박리화외과수술치료료효.방법 60례소화도조기암환자분성량조,33례급여내경점막하박리(endoscopic submucosal dissection,ESD)치료(ESD조),27례급여외과수술치료(외과조).치료과정중관찰량충방법적치료성공솔、생존시간、복발급전이정황、영양상황、불량반응급병발증적발생솔、주원시간급치료비용.결과 ESD조화외과조적치료성공솔、생존시간、복발급전이정황비교차이무통계학의의(P＞0.05);ESD조영양상황체정상치솔90.9％(30/33),외과조영양상황체정상치솔66.7％(18/27);ESD조불량반응급병발증발생솔위9.09％(3/33),외과조불량반응급병발증발생솔위59.2％(16/27).량조영양상황체정상치솔、불량반응급병발증발생솔차이유통계학의의(P＜ 0.05,P＜0.01).ESD조주원시간(14.81±3.27)d,치료비용(10562.01±3060.08)원;외과조주원시간(19.22 ±6.91)d,치료비용(16587.87±5664.50)원.외과조주원시간교ESD조장,치료비용교ESD조귀.결론 소화도조기암ESD치료,여외과수술적료효상당,술후불량반응교외과수술발생솔저,주원시간단,치료비용상대교저,특별시능보류환자소화도적완정성,생활질량현저제고.
Objective To compare the therapeutic efficacies of endoscopic submucosal dissection and surgical operation treatment of early gastrointestinal cancers.Methods Sixty patients with early gastrointestinal cancer were divided into the endoscopic submucosal dissection (ESD) treatment group (n =33patients) and surgical operation treatment group (n =27 patients).During the treatment,success rate,survival time,recurrence and metastasis,nutritional status,adverse reaction and complication rate,hospital stay,and cost of treatment were observed for two groups.Results No statistical significances in success rate,survival time,recurrence and metastasis were found between two groups (P ＞ 0.05).The rate of normal nutritional status value was 90.9％ (30/33) in group ESD and 66.7％ (18/27) in the surgical group with a statistically significant difference between two groups (P ＜ 0.05).The rate of adverse reaction and complication was 9.09％ (3/33) in group ESD and 59.2％ (16/27) in the surgical group with a statistically significant difference between two groups (P ＜ 0.05,P ＜ 0.01).The average length of stay (14,81 ± 3.27) days and the average hospitalization expenses (10562.01 ± 3060.08) Yuan were occurred in the group ESD.The average length of hospital stay (19.22 ± 6.91)days and the average hospitalization expenses (16587.87 ±5664.50)Yuan were occurred in the surgical group.The average length of hospital stay in surgical group was longer 4,41 days than group ESD.The average hospitalization expense in surgical group was 6025.86 yuan more than the ESD group.Conclusions The curative effects of ESD treatment was similar to surgical operation,and there was a lower postoperative adverse reaction rate,a shorter time of hospitalization,a relatively low cost of treatment for ESD treatment compared to the surgical operation.Moreover,ESD treatment can especially keep the gastrointestinal integrity for patients,and the life quality rises significantly.
