CAJ | 학술논문

目的探讨炎症相关指标(白细胞计数、血沉、C-反应蛋白)在预测动脉瘤性蛛网膜下腔出血后迟发性脑缺血的临床价值.方法将动脉瘤性蛛网膜下腔出血患者217例以是否发生迟发型脑缺血(DCI)分为2组,其中DCI组69例,非DCI组148例.回顾性分析217例患者炎症相关指标,并分析其与DCI患者临床预后的关系.结果 DCI组入院炎症相关指标(WBC计数、血沉及C-反应蛋白)均明显高于非DCI组,差异有统计学意义(P＜0.05).随访结果显示DCI组有33例患者死亡,植物生存12例,重残患者12例,与非DCI组相比差异有统计学意义(P＜0.05).Spearman相关性分析显示DCI组格拉斯哥预后评分(GOS)与炎症指标均呈负相关(r=-0.877,-0.683,-0.841,P＜0.05).结论炎症相关指标可作为预测动脉瘤性蛛网膜下腔出血后迟发性脑缺血的工具之一.
목적 탐토염증상관지표(백세포계수、혈침、C-반응단백)재예측동맥류성주망막하강출혈후지발성뇌결혈적림상개치.방법 장동맥류성주망막하강출혈환자217례이시부발생지발형뇌결혈(DCI)분위2조,기중DCI조69례,비DCI조148례.회고성분석217례환자염증상관지표,병분석기여DCI환자림상예후적관계.결과 DCI조입원염증상관지표(WBC계수、혈침급C-반응단백)균명현고우비DCI조,차이유통계학의의(P＜0.05).수방결과현시DCI조유33례환자사망,식물생존12례,중잔환자12례,여비DCI조상비차이유통계학의의(P＜0.05).Spearman상관성분석현시DCI조격랍사가예후평분(GOS)여염증지표균정부상관(r=-0.877,-0.683,-0.841,P＜0.05).결론 염증상관지표가작위예측동맥류성주망막하강출혈후지발성뇌결혈적공구지일.
Objective To investigate the clinical value of inflammation-related factors [white blood cell count,erythrocyte sedimentation rate (ESR),and C-reactive protein] in predicting delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.Methods The aneurysmal subarachnoid hemorrhage in 217 cases according to whether the occurrence of delayed cerebral ischemia were divided into 2 groups:delayed cerebral ischemia (DCI) group (n =69) and non DCI group (n =148).A retrospective analysis of 217 cases of patients was performed with inflammation-related factors,and its relationship with clinical prognosis of patients with DCI was also analyzed.Results The inflammation-related factors (WBC count,erythrocyte sedimentation rate,and C-reactive protein) in DCI group were significantly higher than those in non DCI group with a statistically significant difference (P ＜ 0.05).The follow-up results showed that there were 33 patients died,12 cases of plant survival,and 12 patients with severe disability in DCI group,which had a statistically significant difference relative to non DCI group (P ＜ 0.05).Spearman analysis showed that there was a significantly negative relationship between inflammation-related factors (white blood cell count,ESR,C-reactive protein) and glasgow prognostic score (GOS) in DCI group(r =-0.877,-0.683,-0.841,P ＜0.05).Conclusions The inflammation-related factors can be used as one of method to predict delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.