中国医师杂志
中國醫師雜誌
중국의사잡지
JOURNAL OF CHINESE PHYSICIAN
2014年
9期
1227-1229
,共3页
胆固醇/血液%脂蛋白类,HDL/血液%脂蛋白类,LDL/血液%胃肿瘤/病理学%肿瘤分期%预后
膽固醇/血液%脂蛋白類,HDL/血液%脂蛋白類,LDL/血液%胃腫瘤/病理學%腫瘤分期%預後
담고순/혈액%지단백류,HDL/혈액%지단백류,LDL/혈액%위종류/병이학%종류분기%예후
Cholesterol/blood%Lipoproteins,HDL/blood%Lipoproteins,LDL/blood%Stomach neoplasms/pathology%Neoplasm staging%Prognosis
目的 探讨血清总胆固醇(TC)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)水平与胃癌TNM分期及Lauren's分型间的关系.方法 对157例胃癌患者、80例良性胃病患者及80例正常人采用日立Antinomic Analyzer 7170A全自动生化分析仪测定其外周血脂水平,采用SPSS 19.0统计软件对各组数据进行统计学分析.结果 胃癌组血清TC、HDL、LDL较正常对照组和良性胃病组均明显下降(P＜0.05);胃癌患者血清HDL水平随胃癌TNM分期的增高而降低,且均低于良性胃病组及正常对照组(P＜0.05);胃癌患者Lauren's组织学分型间血清TC、HDL、LDL水平差异无统计学意义(P＞0.05).结论 胃癌患者存在血脂及脂蛋白的代谢异常,血清HDL水平降低可能与胃癌的TNM分期有关,监测血脂水平变化可能对胃癌筛查及预后判断有一定参考价值.
目的 探討血清總膽固醇(TC)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)水平與胃癌TNM分期及Lauren's分型間的關繫.方法 對157例胃癌患者、80例良性胃病患者及80例正常人採用日立Antinomic Analyzer 7170A全自動生化分析儀測定其外週血脂水平,採用SPSS 19.0統計軟件對各組數據進行統計學分析.結果 胃癌組血清TC、HDL、LDL較正常對照組和良性胃病組均明顯下降(P＜0.05);胃癌患者血清HDL水平隨胃癌TNM分期的增高而降低,且均低于良性胃病組及正常對照組(P＜0.05);胃癌患者Lauren's組織學分型間血清TC、HDL、LDL水平差異無統計學意義(P＞0.05).結論 胃癌患者存在血脂及脂蛋白的代謝異常,血清HDL水平降低可能與胃癌的TNM分期有關,鑑測血脂水平變化可能對胃癌篩查及預後判斷有一定參攷價值.
목적 탐토혈청총담고순(TC)、고밀도지단백(HDL)、저밀도지단백(LDL)수평여위암TNM분기급Lauren's분형간적관계.방법 대157례위암환자、80례량성위병환자급80례정상인채용일립Antinomic Analyzer 7170A전자동생화분석의측정기외주혈지수평,채용SPSS 19.0통계연건대각조수거진행통계학분석.결과 위암조혈청TC、HDL、LDL교정상대조조화량성위병조균명현하강(P＜0.05);위암환자혈청HDL수평수위암TNM분기적증고이강저,차균저우량성위병조급정상대조조(P＜0.05);위암환자Lauren's조직학분형간혈청TC、HDL、LDL수평차이무통계학의의(P＞0.05).결론 위암환자존재혈지급지단백적대사이상,혈청HDL수평강저가능여위암적TNM분기유관,감측혈지수평변화가능대위암사사급예후판단유일정삼고개치.
Objective To investigate the correlations of the levels of serum total cholesterol (TC),high density lipoprotein(HDL),and low density lipoprotein (LDL) with tumor node metastasis (TNM) staging and Lauren's classification in gastric cancer.Methods The blood lipid levels of 157 cases of gastric cancers,80 cases of benign gastric diseases,and 80 cases of normal subjects were detected by the Hitachi 7170A automatic biochemical instrument,and these values were statistically compared with SPSS 19.0.Results The contents of serum TC,HDL,and LDL in the group of gastric cancers were lower than those in the groups of normal subjects and benign gastric diseases (P ＜ 0.05).The contents of serum HDL levels were decreased with the increase of the TNM stage in patients with gastric cancer,and were all lower than the benign gastric diseases and the health control group (P ＜ 0.05).No statistically significant correlation was found in the levels of serum TC,HDL,and LDL in Lauren's histological types of gastric cancers (P ＜0.05).Conclusions Abnormal lipid metabolism had already appeared in gastric cancer,and the decreased serum HDL levels was correlated with TNM stage of gastric cancer.Detection of the changes of lipid levels in patients might be beneficial to the screening and prognosis of gastric cancer.
