中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2013年
6期
618-621
,共4页
赵振国%张鑫鑫%于胜吉%宋艳%徐立斌%刘婷%叶智斌
趙振國%張鑫鑫%于勝吉%宋豔%徐立斌%劉婷%葉智斌
조진국%장흠흠%우성길%송염%서립빈%류정%협지빈
平滑肌肉瘤%软组织肉瘤%转移%预后
平滑肌肉瘤%軟組織肉瘤%轉移%預後
평활기육류%연조직육류%전이%예후
Leiomyosarcoma%Soft tissue sarcoma%Metastasis%Prognosis
目的 探讨四肢或躯干软组织平滑肌肉瘤的临床特征、治疗方法和预后情况.方法 回顾性分析1999年1月至2012年12月收治的18例四肢或躯干平滑肌肉瘤患者的临床资料.7例外院局部切除术后；2例外院活检术后；8例外院多次术后复发；l例初诊于我院.l例行肿瘤边缘切除；17例行扩大切除.18例患者均获得随访,随访时间16 ～ 158个月.结果 随访期间9例(50.0％)发生肺转移,其中5例合并局部复发(27.8％).全组死亡10例,生存8例.10例死亡患者中,7例死于肿瘤进展,3例死于非肿瘤因素.8例生存的患者,2例为带瘤生存.全组5年总生存率为59.2％.结论 四肢或躯干软组织平滑肌肉瘤是一种少见的恶性肿瘤,多见于老年人,一般表现为软组织内肿物.复发和转移多见,预后差.手术治疗结合放疗是主要治疗方法.
目的 探討四肢或軀榦軟組織平滑肌肉瘤的臨床特徵、治療方法和預後情況.方法 迴顧性分析1999年1月至2012年12月收治的18例四肢或軀榦平滑肌肉瘤患者的臨床資料.7例外院跼部切除術後；2例外院活檢術後；8例外院多次術後複髮；l例初診于我院.l例行腫瘤邊緣切除；17例行擴大切除.18例患者均穫得隨訪,隨訪時間16 ～ 158箇月.結果 隨訪期間9例(50.0％)髮生肺轉移,其中5例閤併跼部複髮(27.8％).全組死亡10例,生存8例.10例死亡患者中,7例死于腫瘤進展,3例死于非腫瘤因素.8例生存的患者,2例為帶瘤生存.全組5年總生存率為59.2％.結論 四肢或軀榦軟組織平滑肌肉瘤是一種少見的噁性腫瘤,多見于老年人,一般錶現為軟組織內腫物.複髮和轉移多見,預後差.手術治療結閤放療是主要治療方法.
목적 탐토사지혹구간연조직평활기육류적림상특정、치료방법화예후정황.방법 회고성분석1999년1월지2012년12월수치적18례사지혹구간평활기육류환자적림상자료.7예외원국부절제술후；2예외원활검술후；8예외원다차술후복발；l례초진우아원.l례행종류변연절제；17례행확대절제.18례환자균획득수방,수방시간16 ～ 158개월.결과 수방기간9례(50.0％)발생폐전이,기중5례합병국부복발(27.8％).전조사망10례,생존8례.10례사망환자중,7례사우종류진전,3례사우비종류인소.8례생존적환자,2례위대류생존.전조5년총생존솔위59.2％.결론 사지혹구간연조직평활기육류시일충소견적악성종류,다견우노년인,일반표현위연조직내종물.복발화전이다견,예후차.수술치료결합방료시주요치료방법.
Objective To explore the clinical feature,suitable treatment and prognosis of soft tissue leiomyosarcoma of the trunk and extremities.Methods Clinical data of 18 cases of pathologically confirmed soft tissue leiomyosarcoma of the trunk and extremities from January 1999 to December 2012 were analyzed retrospectively.Primary tumors in 7 cases were marginally excised before admitted to our hospital,2 had open biopsy before admission to our hospital,and 8 cases had local relapse at admission; Only one patient took our institute as the first visit.Seventeen cases were performed extended excision of tumors and 1 case underwent marginal resection.All the patients were followed up and the follow-up period was from 16 to 158 months.Results During follow-up period,9 patients developed lung metastasis,and local recurrence occurred in 5 patients.Ten patients died and 8 survived.Of the ten dead cases,seven died of tumor progression and 3 died from non-tumor factors.In the 8 patients survived,2 survived with tumor.The 5-year overall survival rate was 59.2％.Conclusion Soft tissue leiomyosarcoma of the trunk and extremities are rare malignant tumors,mostly occurred in elder patients and presenting soft tissue mass.Local recurrence and distant metastasis are common and associated with a poor prognosis.Surgical excision combined with adjuvant radiation is the common treatment strategy.
