中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2013年
8期
869-871
,共3页
食管癌%肿瘤复发%三维适形放疗
食管癌%腫瘤複髮%三維適形放療
식관암%종류복발%삼유괄형방료
Esophageal carcinoma%Neoplasm recurrence%Three dimensional conformal radiotherapy
目的 探讨食管癌术后局部复发转移的放疗效果.方法 回顾性分析食管癌术后局部复发转移行放疗的60例患者临床资料,单纯吻合口复发8例,吻合口复发+纵隔淋巴结转移21例,腹腔淋巴结转移5例,单纯锁骨上淋巴结转移9例,单纯纵隔淋巴结转移11例,锁骨上区+纵隔淋巴结转移6例.所有患者均采用三维适形放疗,剂量50～70 Gy.观察放疗后的近期疗效、生存率及急性放射不良反应.结果 患者近期总有效率为78.3％.1、2、3年生存率分别为100％、50.0％、30.0％,中位生存期为15.8个月.急性放射不良反应包括:急性放射性食管炎Ⅰ、Ⅱ级16例(26.7％,16/60),Ⅲ级4例(6.7％,4/60)；急性放射性肺炎11例(18.3％,11/60)；骨髓抑制Ⅰ、Ⅱ级3例(5％,3/60)；急性心脏损伤1例(1.7％,1/60).结论 食管癌术后局部复发行三维适形放疗是一种疗效较好的治疗方法,缩短了放疗疗程,提高了生存率.
目的 探討食管癌術後跼部複髮轉移的放療效果.方法 迴顧性分析食管癌術後跼部複髮轉移行放療的60例患者臨床資料,單純吻閤口複髮8例,吻閤口複髮+縱隔淋巴結轉移21例,腹腔淋巴結轉移5例,單純鎖骨上淋巴結轉移9例,單純縱隔淋巴結轉移11例,鎖骨上區+縱隔淋巴結轉移6例.所有患者均採用三維適形放療,劑量50～70 Gy.觀察放療後的近期療效、生存率及急性放射不良反應.結果 患者近期總有效率為78.3％.1、2、3年生存率分彆為100％、50.0％、30.0％,中位生存期為15.8箇月.急性放射不良反應包括:急性放射性食管炎Ⅰ、Ⅱ級16例(26.7％,16/60),Ⅲ級4例(6.7％,4/60)；急性放射性肺炎11例(18.3％,11/60)；骨髓抑製Ⅰ、Ⅱ級3例(5％,3/60)；急性心髒損傷1例(1.7％,1/60).結論 食管癌術後跼部複髮行三維適形放療是一種療效較好的治療方法,縮短瞭放療療程,提高瞭生存率.
목적 탐토식관암술후국부복발전이적방료효과.방법 회고성분석식관암술후국부복발전이행방료적60례환자림상자료,단순문합구복발8례,문합구복발+종격림파결전이21례,복강림파결전이5례,단순쇄골상림파결전이9례,단순종격림파결전이11례,쇄골상구+종격림파결전이6례.소유환자균채용삼유괄형방료,제량50～70 Gy.관찰방료후적근기료효、생존솔급급성방사불량반응.결과 환자근기총유효솔위78.3％.1、2、3년생존솔분별위100％、50.0％、30.0％,중위생존기위15.8개월.급성방사불량반응포괄:급성방사성식관염Ⅰ、Ⅱ급16례(26.7％,16/60),Ⅲ급4례(6.7％,4/60)；급성방사성폐염11례(18.3％,11/60)；골수억제Ⅰ、Ⅱ급3례(5％,3/60)；급성심장손상1례(1.7％,1/60).결론 식관암술후국부복발행삼유괄형방료시일충료효교호적치료방법,축단료방료료정,제고료생존솔.
Objective To investigate the effects of radiotherapy of patients with post-operative locoregional recurrence of esophageal carcinoma.Methods Retrospectively analyzed the clinical data of 60 patients with esophageal carcinoma who developed post-operative loco-regional recurrence.There were 8 patients with anastomosis relapse,21 with anastomosis and mediastinal lymph nodes metastasis,5 with abdominal lymph node metastasis,9 with supra clavicular lymph node metastasis,11 with mediastinal lymph node metastasis and 6 with mediastinal and supra-clavicular lynph node metastasis.Three-dimensional conformal radiation therapy was used to treat all the patients,with a total radiation dose of 50-70 Gy.Short-term effect,survival and adverse reactions of acute radiation were observed after radiotherapy.Results The effective rate of short term was 78.3％.The 1st,2nd and 3th year overall survival rates were 100％,50.0％,30.0％,respectively,and the middle survival phase was 15.8 months.Acute radiation side effects include:16 cases of acute radiation esophagitis grade Ⅰ,Ⅱ (26.7％,16/60),4 cases of Ⅲ grade (6.7％,4/60);11 cases of acute radiation pneumonitis (18.3％,11/60);3 cases of bone marrow suppression Ⅰ,Ⅱ grade (5％,3/60) and acute cardiac injury in 1 case (1.7％,1/60).Conclusion Radiotherapy may improve the survival rate and the reduce the therapy phase of esophageal carcinoma patients with postoperative recurrence which is a good method for patients.
