中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2014年
2期
144-147
,共4页
获得性免疫缺陷综合征%肺部感染%生存质量%中西医结合治疗
穫得性免疫缺陷綜閤徵%肺部感染%生存質量%中西醫結閤治療
획득성면역결함종합정%폐부감염%생존질량%중서의결합치료
AIDS%Lung infection%Quality of life%Chinese and western medicines
目的 探讨中西医药物结合治疗对获得性免疫缺陷综合征(AIDS)合并肺部感染患者生存质量的改善作用.方法 将60例AIDS合并肺部感染患者按照随机、双盲对照方法分为两组,西药±安慰剂组30例,西药+中药组30例,患者住院观察时间均为4周.用WHO QOL-HIV生存质量量表加上AIDS相关条目,对两组患者治疗前后生存质量进行调查.结果 西药+中药组与西药+安慰剂组治疗前WHO QOL-HIV量表中生活质量、活动能力、健康状况、睡眠、工作能力、休闲机会得分差异均无统计学意义(P均＞0.05),治疗后西药+中药组上述各指标得分均高于西药+安慰剂组[(3.78±0.69)、(2.90±0.77)分,(3.55±0.67)、(2.75 ±0.85)分,(3.55±0.67)、(2.75±0.85)分,(3.18±0.72)、(2.85±0.68)分,(3.66±0.70)、(3.35±0.57)分,(3.03±0.73)、(2.95±0.85)分],差异均有统计学意义(t值分别为-2.79、-2.79、-4.28、-3.08、-4.08、-2.56,P均＜0.05);西药+中药组与西药+安慰剂组治疗前WHO QOL-HIV量表中自己满意度、性生活、人类获得性免疫缺陷病毒对身体影响、生活意义、精力评分差异均无统计学意义(P均＞0.05),治疗后西药+中药组各指标得分高于西药+安慰剂组[(3.51±0.67)、(2.93±0.71)分,(3.13±0.46)、(2.86±0.74)分,(3.96±0.71)、(3.45±0.98)分,(3.66±0.72)、(3.23±0.88)分,(3.23±0.67)、(2.90±0.65)分],差异均有统计学意义(t值分别为-4.38、-2.34、-3.75、-2.76、-2.38,P均＜0.05),人类获得性免疫缺陷病毒对精神影响组间治疗前比较差异无统计学意义(P＞0.05),治疗后西药+中药组低于西药+安慰剂组[(3.05±0.90)、(3.46±0.87)分],差异有统计学意义(t=2.31,P＜0.05).结论 中药联合西药治疗能明显改善AIDS合并肺部感染患者的生存质量.
目的 探討中西醫藥物結閤治療對穫得性免疫缺陷綜閤徵(AIDS)閤併肺部感染患者生存質量的改善作用.方法 將60例AIDS閤併肺部感染患者按照隨機、雙盲對照方法分為兩組,西藥±安慰劑組30例,西藥+中藥組30例,患者住院觀察時間均為4週.用WHO QOL-HIV生存質量量錶加上AIDS相關條目,對兩組患者治療前後生存質量進行調查.結果 西藥+中藥組與西藥+安慰劑組治療前WHO QOL-HIV量錶中生活質量、活動能力、健康狀況、睡眠、工作能力、休閒機會得分差異均無統計學意義(P均＞0.05),治療後西藥+中藥組上述各指標得分均高于西藥+安慰劑組[(3.78±0.69)、(2.90±0.77)分,(3.55±0.67)、(2.75 ±0.85)分,(3.55±0.67)、(2.75±0.85)分,(3.18±0.72)、(2.85±0.68)分,(3.66±0.70)、(3.35±0.57)分,(3.03±0.73)、(2.95±0.85)分],差異均有統計學意義(t值分彆為-2.79、-2.79、-4.28、-3.08、-4.08、-2.56,P均＜0.05);西藥+中藥組與西藥+安慰劑組治療前WHO QOL-HIV量錶中自己滿意度、性生活、人類穫得性免疫缺陷病毒對身體影響、生活意義、精力評分差異均無統計學意義(P均＞0.05),治療後西藥+中藥組各指標得分高于西藥+安慰劑組[(3.51±0.67)、(2.93±0.71)分,(3.13±0.46)、(2.86±0.74)分,(3.96±0.71)、(3.45±0.98)分,(3.66±0.72)、(3.23±0.88)分,(3.23±0.67)、(2.90±0.65)分],差異均有統計學意義(t值分彆為-4.38、-2.34、-3.75、-2.76、-2.38,P均＜0.05),人類穫得性免疫缺陷病毒對精神影響組間治療前比較差異無統計學意義(P＞0.05),治療後西藥+中藥組低于西藥+安慰劑組[(3.05±0.90)、(3.46±0.87)分],差異有統計學意義(t=2.31,P＜0.05).結論 中藥聯閤西藥治療能明顯改善AIDS閤併肺部感染患者的生存質量.
목적 탐토중서의약물결합치료대획득성면역결함종합정(AIDS)합병폐부감염환자생존질량적개선작용.방법 장60례AIDS합병폐부감염환자안조수궤、쌍맹대조방법분위량조,서약±안위제조30례,서약+중약조30례,환자주원관찰시간균위4주.용WHO QOL-HIV생존질량량표가상AIDS상관조목,대량조환자치료전후생존질량진행조사.결과 서약+중약조여서약+안위제조치료전WHO QOL-HIV량표중생활질량、활동능력、건강상황、수면、공작능력、휴한궤회득분차이균무통계학의의(P균＞0.05),치료후서약+중약조상술각지표득분균고우서약+안위제조[(3.78±0.69)、(2.90±0.77)분,(3.55±0.67)、(2.75 ±0.85)분,(3.55±0.67)、(2.75±0.85)분,(3.18±0.72)、(2.85±0.68)분,(3.66±0.70)、(3.35±0.57)분,(3.03±0.73)、(2.95±0.85)분],차이균유통계학의의(t치분별위-2.79、-2.79、-4.28、-3.08、-4.08、-2.56,P균＜0.05);서약+중약조여서약+안위제조치료전WHO QOL-HIV량표중자기만의도、성생활、인류획득성면역결함병독대신체영향、생활의의、정력평분차이균무통계학의의(P균＞0.05),치료후서약+중약조각지표득분고우서약+안위제조[(3.51±0.67)、(2.93±0.71)분,(3.13±0.46)、(2.86±0.74)분,(3.96±0.71)、(3.45±0.98)분,(3.66±0.72)、(3.23±0.88)분,(3.23±0.67)、(2.90±0.65)분],차이균유통계학의의(t치분별위-4.38、-2.34、-3.75、-2.76、-2.38,P균＜0.05),인류획득성면역결함병독대정신영향조간치료전비교차이무통계학의의(P＞0.05),치료후서약+중약조저우서약+안위제조[(3.05±0.90)、(3.46±0.87)분],차이유통계학의의(t=2.31,P＜0.05).결론 중약연합서약치료능명현개선AIDS합병폐부감염환자적생존질량.
Objective To investigate and evaluate the improvement of the quality of life of pulmonary infection in AIDS patients treated by Chinese traditional treatment combined Western medicines treatment.Methods Sixty cases with HIV infection combined with pulmonary infection were selected as our subjects.They were randomly divided into two groups and each group was 30 cases.Patients in western medicine group were given medicine plus placebo,and in Chinese medicine group were given west medicine combined with traditional Chinese medicine.Patients hospitalized for 4 weeks.WHO QOL-HIV plus AIDS-related quality of life scale were used to collect the information about quality of life.Results There were no significant difference between two groups in terms of quality of life,life activity,health status,sleep status,ability to work,leisure opportunities scores at before treatment (P ＞ 0.05).After treatment,the score of quality of life,life activity,health status,sleep status,ability to work,leisure opportunities in patients of Chinese group were (3.78 ± 0.69),(3.55 ± 0.67),(3.55 ± 0.67),(3.18 ± 0.72),(3.66 ± 0.70),(3.03 ± 0.73) respectively,higher than that of western medicine group ((2.90 ± 0.77),(2.75 ± 0.85),(2.75 ± 0.85),(2.85 ± 0.68),(3.35 ± 0.57),(2.95 ± 0.85) respectively,t =-2.791,-2.791,-4.28,-3.08,-4.08,-2.56,P ＜ 0.05).There were no significant differences between the two groups in the terms of the score of satisfaction,sex ability,HIV impaction on the body,the meaning of life,the energy aspects of patients at before treatment (P ＞ 0.05),but after treatment,these scores in Chinese medicine group were higher that in the control group ((3.51 ± 0.67) vs.(2.93 ±0.71),(3.13±0.46) vs.(2.86±0.74),(3.96±0.71) vs.(3.45 ±0.98),(3.66±0.72) vs.(3.23 ± 0.88),(3.23 ± 0.67) vs.(2.90 ± 0.65)),and the differences were statistically significant (t =-4.38,-2.34,-3.75,-2.76,-2.38,P ＜ 0.05).There was no significant difference in the term of the mental effect of HIV within groups at before treatment,but after treatment,the score in Chinese group was lower than the Western group ((3.05 ± 0.90) vs.(3.46 ± 0.87),t =2.31,P ＜ 0.05).Conclusion Chinese medicine combined western medicine can significant improve the quality of life of HIV patients with pulmonary infection.
