中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2014年
8期
792-797
,共6页
李伟哲%高明%王艳秀%陈朔华%苏晓茹%韩红锋%齐艳红%李玉卿%赵性泉
李偉哲%高明%王豔秀%陳朔華%囌曉茹%韓紅鋒%齊豔紅%李玉卿%趙性泉
리위철%고명%왕염수%진삭화%소효여%한홍봉%제염홍%리옥경%조성천
代谢综合征%踝臂指数%外周动脉疾病
代謝綜閤徵%踝臂指數%外週動脈疾病
대사종합정%과비지수%외주동맥질병
Metabolic syndrome%Ankle-brachial index%Peripheral arterial disease
目的 探讨代谢综合征(MS)对中老年人群踝臂指数(ABI)的影响.方法 采用前瞻性队列研究,在2006-2007年参加健康体检的101 510例开滦集团职工中随机分层抽取5 852例作为研究对象,进行统一问卷调查及血液生化检查,符合入选标准的为5 440例.于2010-2011年度进行第3次健康体检并测量ABI,最终纳入统计分析的有效数据为4 729例.依据2007年中国成人血脂异常防治指南对2004年CDS建议的修订作为诊断标准,将研究人群分为MS组和非MS组,对影响ABI的相关危险因素进行多因素Logistic回归分析.结果 MS组和非MS组的平均ABI分别为1.09±0.11、1.09±0.09,组间比较差异无统计学意义(P =0.807).ABI≤0.9分别为49例(5.2％)、120例(3.2％),组间比较差异有统计学意义(x2=7.41,P＜0.05);影响ABI的多因素logistic回归分析显示:ABI≤0.9、男性人群与MS患者具有相关性(RR:1.48,95％ CI:1.04～2.08、RR:1.56,95％ CI:1.02 ～2.37;P均＜0.05).结论 在中老年人群MS是影响远期ABI的独立危险因素,且在男性中更加显著.
目的 探討代謝綜閤徵(MS)對中老年人群踝臂指數(ABI)的影響.方法 採用前瞻性隊列研究,在2006-2007年參加健康體檢的101 510例開灤集糰職工中隨機分層抽取5 852例作為研究對象,進行統一問捲調查及血液生化檢查,符閤入選標準的為5 440例.于2010-2011年度進行第3次健康體檢併測量ABI,最終納入統計分析的有效數據為4 729例.依據2007年中國成人血脂異常防治指南對2004年CDS建議的脩訂作為診斷標準,將研究人群分為MS組和非MS組,對影響ABI的相關危險因素進行多因素Logistic迴歸分析.結果 MS組和非MS組的平均ABI分彆為1.09±0.11、1.09±0.09,組間比較差異無統計學意義(P =0.807).ABI≤0.9分彆為49例(5.2％)、120例(3.2％),組間比較差異有統計學意義(x2=7.41,P＜0.05);影響ABI的多因素logistic迴歸分析顯示:ABI≤0.9、男性人群與MS患者具有相關性(RR:1.48,95％ CI:1.04～2.08、RR:1.56,95％ CI:1.02 ～2.37;P均＜0.05).結論 在中老年人群MS是影響遠期ABI的獨立危險因素,且在男性中更加顯著.
목적 탐토대사종합정(MS)대중노년인군과비지수(ABI)적영향.방법 채용전첨성대렬연구,재2006-2007년삼가건강체검적101 510례개란집단직공중수궤분층추취5 852례작위연구대상,진행통일문권조사급혈액생화검사,부합입선표준적위5 440례.우2010-2011년도진행제3차건강체검병측량ABI,최종납입통계분석적유효수거위4 729례.의거2007년중국성인혈지이상방치지남대2004년CDS건의적수정작위진단표준,장연구인군분위MS조화비MS조,대영향ABI적상관위험인소진행다인소Logistic회귀분석.결과 MS조화비MS조적평균ABI분별위1.09±0.11、1.09±0.09,조간비교차이무통계학의의(P =0.807).ABI≤0.9분별위49례(5.2％)、120례(3.2％),조간비교차이유통계학의의(x2=7.41,P＜0.05);영향ABI적다인소logistic회귀분석현시:ABI≤0.9、남성인군여MS환자구유상관성(RR:1.48,95％ CI:1.04～2.08、RR:1.56,95％ CI:1.02 ～2.37;P균＜0.05).결론 재중노년인군MS시영향원기ABI적독립위험인소,차재남성중경가현저.
Objective To investigate the impact of metabolic syndrome (MS) in the elderly anklebrachial index(ABI).Methods A prospective cohort study was conducted.Five hundred and eighty-two people from 101 510 cases who participated in the 2006-2007 of healthy Kailuan Group employees by stratified random decimation were selected as subjects.Unified questionnaires and blood tests were performed and 5 440 cases met the inclusion criteria ABI was measured from 2010 to 2011 at the third health examination and 4 729 final valid data were used to make statistical analysis.Based on 2007 Chinese adult dyslipidemia prevention guide for 2004 CDS of the proposed amendments as diagnostic criteria,the study population was divided into MS group and non-MS group.Multivariate logistic regression was used to identify the risk factors.Results The average ABI in MS group and the non-MS group were (1.09 ± 0.11),(1.09 ± 0.09),and the difference between groups was not statistically significant(P =0.807).The rate of people with ABI ≤ 0.9 in MS group and the non-MS group were 49(5.2％) and 120 (3.2％),and the difference between groups was statistically significant (x2 =7.41,P ＜ 0.05).Multivariate logistic regression analysis showed that the factors of male and ABI ≤ 0.9 were related to MS((RR:1.48,95％CI:1.04-2.08;RR:1.56,95％CI:1.02-2.37;P ＜0.05).Conclusion In the elderly population,MS is an independent risk factor which impact on ABI especially in male population.
