中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2014年
8期
828-830
,共3页
胎膜早破%早产%绒毛膜羊膜炎%C反应蛋白%宫颈分泌物细菌涂片
胎膜早破%早產%絨毛膜羊膜炎%C反應蛋白%宮頸分泌物細菌塗片
태막조파%조산%융모막양막염%C반응단백%궁경분비물세균도편
Premature rupture of membranes%Preterm%Chorioamnionitis%C reactive protein%Cervical secretions smear
目的 探讨联合检测C反应蛋白、宫颈分泌物细菌涂片对未足月胎膜早破(PPROM)合并绒毛膜羊膜炎诊断的临床价值.方法 通过对80例PPROM(PPROM组)患者C反应蛋白测定及宫颈分泌物细菌涂片检查,将诊断为绒毛膜羊膜炎55例及无绒毛膜羊膜炎25例做为研究对象分析C反应蛋白及宫颈细菌涂片检查结果的敏感性、特异性、阳性预测值、阴性预测值,同时选择相同孕周的未足月无胎膜早破孕妇60例作为PPROM组的对照组.结果 PPROM组C反应蛋白及宫颈分泌物细菌涂片的阳性率均高于对照组,差异均有统计学意义(x2值分别为50.24、54.81,P均<0.05).C反应蛋白诊断未足月胎膜早破患者80例的绒毛膜羊膜炎的敏感性、特异性、阳性预测值、阴性预测值分别为58.18%、63.64%、36.00%、32.00%,宫颈分泌物细菌涂片分别为66.67%、67.31%、29.03%、28.57%,C反应蛋白及宫颈分泌物细菌涂片两者同时阳性诊断绒毛膜羊膜炎的敏感性、特异性、阳性预测值、阴性预测值分别为69.09%、88.00%、92.68%、56.41%.结论 联合检测C反应蛋白及宫颈分泌物细菌涂片可提高对PPROM孕妇合并绒毛膜羊膜炎诊断的特异性和阳性预测值.
目的 探討聯閤檢測C反應蛋白、宮頸分泌物細菌塗片對未足月胎膜早破(PPROM)閤併絨毛膜羊膜炎診斷的臨床價值.方法 通過對80例PPROM(PPROM組)患者C反應蛋白測定及宮頸分泌物細菌塗片檢查,將診斷為絨毛膜羊膜炎55例及無絨毛膜羊膜炎25例做為研究對象分析C反應蛋白及宮頸細菌塗片檢查結果的敏感性、特異性、暘性預測值、陰性預測值,同時選擇相同孕週的未足月無胎膜早破孕婦60例作為PPROM組的對照組.結果 PPROM組C反應蛋白及宮頸分泌物細菌塗片的暘性率均高于對照組,差異均有統計學意義(x2值分彆為50.24、54.81,P均<0.05).C反應蛋白診斷未足月胎膜早破患者80例的絨毛膜羊膜炎的敏感性、特異性、暘性預測值、陰性預測值分彆為58.18%、63.64%、36.00%、32.00%,宮頸分泌物細菌塗片分彆為66.67%、67.31%、29.03%、28.57%,C反應蛋白及宮頸分泌物細菌塗片兩者同時暘性診斷絨毛膜羊膜炎的敏感性、特異性、暘性預測值、陰性預測值分彆為69.09%、88.00%、92.68%、56.41%.結論 聯閤檢測C反應蛋白及宮頸分泌物細菌塗片可提高對PPROM孕婦閤併絨毛膜羊膜炎診斷的特異性和暘性預測值.
목적 탐토연합검측C반응단백、궁경분비물세균도편대미족월태막조파(PPROM)합병융모막양막염진단적림상개치.방법 통과대80례PPROM(PPROM조)환자C반응단백측정급궁경분비물세균도편검사,장진단위융모막양막염55례급무융모막양막염25례주위연구대상분석C반응단백급궁경세균도편검사결과적민감성、특이성、양성예측치、음성예측치,동시선택상동잉주적미족월무태막조파잉부60례작위PPROM조적대조조.결과 PPROM조C반응단백급궁경분비물세균도편적양성솔균고우대조조,차이균유통계학의의(x2치분별위50.24、54.81,P균<0.05).C반응단백진단미족월태막조파환자80례적융모막양막염적민감성、특이성、양성예측치、음성예측치분별위58.18%、63.64%、36.00%、32.00%,궁경분비물세균도편분별위66.67%、67.31%、29.03%、28.57%,C반응단백급궁경분비물세균도편량자동시양성진단융모막양막염적민감성、특이성、양성예측치、음성예측치분별위69.09%、88.00%、92.68%、56.41%.결론 연합검측C반응단백급궁경분비물세균도편가제고대PPROM잉부합병융모막양막염진단적특이성화양성예측치.
Objective To explore the clinical significance in combined detection of C-reactive protein and the cervical secretion smear in chorioamnionitis with preterm premature rupture of membranes (PPROM).Methods Eighty patients with PPROM (PPROM group) were selected and divided into chorioamnionitis group (n =55) and without chorioamnionitis(n =25) according to the diagnosis.The levels of C-reactive protein and cervical smear were analysis,including sensitivity,specificity,positive predictive value and negative predictive value.Sixty cases of preterm no premature rupture of membranes pregnant women with the same gestational age were chosed as the control group.Results The positive rate of CRP and cervical secretions smear in PPROM group were higher than those of control group,and the differences were statistically significant (x2 =50.24,54.81 ;P < 0.05).The sensitivity,specificity,positive predictive value and negative predictive value by the CRP diagnosis of chorioamnionitis in patients with PPROM were 58.18%,63.64%,36.00%,32.00% respectively.Those indices of cervical secretions smear diagnosis were 66.67%,67.31%,29.03%,28.57% respectively.The sensitivity,specificity,positive predictive value regarding of CRP and cervical secretions smear joint inspection diagnosis of chorioamnionitis were 69.09%,88.00%,92.68%,56.41% respectively.Conclusion The inspection of CRP combined with cervical secretion smear can improve specificity and positive predictive value of chorioamnionitis diagnosis with PPROM pregnant women.