中华病理学杂志
中華病理學雜誌
중화병이학잡지
Chinese Journal of Pathology
2013年
10期
665-668
,共4页
乳腺疾病%肉芽肿性乳腺炎%病理学,临床
乳腺疾病%肉芽腫性乳腺炎%病理學,臨床
유선질병%육아종성유선염%병이학,림상
Breast diseases%Granulomatous mastitis%Pathology,clinical
目的 分析肉芽肿性小叶性乳腺炎伴发乳腺导管扩张症的临床病理特征.方法 收集2005年8月至2013年5月诊断的此类病例32例,对其临床和组织病理学资料进行回顾性分析.结果 患者年龄26～45岁,2例未生育,其余有生育史,其中14例患侧乳腺未哺乳或哺乳障碍.大体检查乳腺肿块直径3～12 cm,与周围组织界限不清,切面见小脓腔或小囊腔,直径0.1～0.5 cm,腔内有灰白或淡黄色分泌物.镜下观察32例均有肉芽肿性小叶性乳腺炎表现,在此基础上均可见乳腺导管扩张症.11例曾行抗生素治疗无效,12例因切开引流致皮肤窦道形成.术后随访5 ～ 90个月,3例患侧复发,1例对侧发生肉芽肿性小叶性乳腺炎伴发乳腺导管扩张症,2例对侧发生肉芽肿性小叶性乳腺炎,4例失访.结论 肉芽肿性小叶性乳腺炎可与乳腺导管扩张症伴发,准确诊断有助于针对性治疗和减少复发.
目的 分析肉芽腫性小葉性乳腺炎伴髮乳腺導管擴張癥的臨床病理特徵.方法 收集2005年8月至2013年5月診斷的此類病例32例,對其臨床和組織病理學資料進行迴顧性分析.結果 患者年齡26～45歲,2例未生育,其餘有生育史,其中14例患側乳腺未哺乳或哺乳障礙.大體檢查乳腺腫塊直徑3～12 cm,與週圍組織界限不清,切麵見小膿腔或小囊腔,直徑0.1～0.5 cm,腔內有灰白或淡黃色分泌物.鏡下觀察32例均有肉芽腫性小葉性乳腺炎錶現,在此基礎上均可見乳腺導管擴張癥.11例曾行抗生素治療無效,12例因切開引流緻皮膚竇道形成.術後隨訪5 ～ 90箇月,3例患側複髮,1例對側髮生肉芽腫性小葉性乳腺炎伴髮乳腺導管擴張癥,2例對側髮生肉芽腫性小葉性乳腺炎,4例失訪.結論 肉芽腫性小葉性乳腺炎可與乳腺導管擴張癥伴髮,準確診斷有助于針對性治療和減少複髮.
목적 분석육아종성소협성유선염반발유선도관확장증적림상병리특정.방법 수집2005년8월지2013년5월진단적차류병례32례,대기림상화조직병이학자료진행회고성분석.결과 환자년령26～45세,2례미생육,기여유생육사,기중14례환측유선미포유혹포유장애.대체검사유선종괴직경3～12 cm,여주위조직계한불청,절면견소농강혹소낭강,직경0.1～0.5 cm,강내유회백혹담황색분비물.경하관찰32례균유육아종성소협성유선염표현,재차기출상균가견유선도관확장증.11례증행항생소치료무효,12례인절개인류치피부두도형성.술후수방5 ～ 90개월,3례환측복발,1례대측발생육아종성소협성유선염반발유선도관확장증,2례대측발생육아종성소협성유선염,4례실방.결론 육아종성소협성유선염가여유선도관확장증반발,준학진단유조우침대성치료화감소복발.
Objective To study the clinicopathologic features of granulomatous lobular mastitis and mammary duct ectasia.Methods The clinicopathologic data from August 2005 to May 2013 of 32 cases of granulomatous lobular mastitis and mammary duct ectasia were retrospectively reviewed.Results The age of patients ranged from 26 to 45 years.Two patients had no history of delivery.Fourteen patients had no history of lactation or lactational disorder in the lesional side.Most of the remaining patients had history of breast feeding.Gross examination showed that the lesions were poorly circumscribed and varied from 3 to 12 cm in greatest dimension.Tiny abscess cavities,ranging from 0.1 to 0.5 cm in diameter and containing light yellowish to greyish secretion,were demonstrated.Histologic examination showed granuloma formation and ductal dilatation.Eleven patients had received antibiotic treatment.Twelve cases were complicated by sinus formation related to skin incision and drainage.The duration of follow-up ranged from 5 to 90 months.Three cases showed ipsilateral recurrence and 3 cases had similar pathology in the contralateral breast.Four patients defaulted follow-up.Conclusions Granulomatous lobular mastitis is associated with mammary duct ectasia.Accurate pathologic diagnosis is prudent for clinical management and control of local recurrence.
