CAJ | 학술논문

目的比较治疗外阴阴道霉菌感染的两种不同用药方案的最小成本.方法运用最小成本分析法(CMA)对氟康唑胶囊+硝酸咪康唑软胶囊+百安洗液(A组)、伊曲康唑胶囊+克霉唑栓+碳酸氢钠溶液(B组)两种给药方案进行药物经济学分析.结果两组成本分别是215.59元和159.94元,总有效率分别是96.9％和98.4％,总不良反应率分别是14.1％和12.5％,两组总有效率和总不良反应率无统计学差异(P＞0.05).结论在达到相同的治疗效果及总不良反应率无差异的情况下B组的最小成本低于A组,经济学评价效果优于A组.
목적 비교치료외음음도매균감염적량충불동용약방안적최소성본.방법 운용최소성본분석법(CMA)대불강서효낭+초산미강서연효낭+백안세액(A조)、이곡강서효낭+극매서전+탄산경납용액(B조)량충급약방안진행약물경제학분석.결과 량조성본분별시215.59원화159.94원,총유효솔분별시96.9％화98.4％,총불량반응솔분별시14.1％화12.5％,량조총유효솔화총불량반응솔무통계학차이(P＞0.05).결론 재체도상동적치료효과급총불량반응솔무차이적정황하B조적최소성본저우A조,경제학평개효과우우A조.
Objective To compare the minimum cost of different therapeutic schedules of mycotic vaginitis.Methods The cost analysis method was applied to analyze the pharmacoeconomics of two groups of treatments,which were group A (fluconazole capsule combined with miconazole soft capsule and baian lotion) and group B (itraconazole capsule combined with clotrimazole vaginal suppository and soda solution).Results The costs of two treatments were 215.59 Yuan and 159.94 Yuan with effective rates of 96.9％ and 98.4％ respectively.Rates of drug adverse reaction were 14.1％ and 12.5％.Therefore,therapeutic regimens of two groups had no statistical difference on the respects of the effectiveness and adverse drug reaction (P ＞ 0.05).Conclusion Under the conditions that the therapeutic effect and adverse drug reactions had no statistical significant difference,the minimum cost of group B is lower than that of group A.Consequently the evaluation of pharmacoeconomics of group B is superior to group A.