CAJ | 학술논문

目的了解成人散发性腹泻病毒感染情况,为临床防治提供依据.方法收集上海市第五人民医院肠道门诊2012年5月至2013年4月腹泻患者粪便标本708份,送上海市闵行区疾病预防控制中心采用反转录(RT)-PCR进行病毒检测.统计学处理采用Pearson卡方检验和Fisher确切概率检验.结果 708份粪便标本中,检出诺如病毒G Ⅰ型7份,占0.99％;诺如病毒GⅡ型150份,占21.19％;轮状病毒21份,占2.97％;星状病毒3份,占0.42％;腺病毒4份,占0.56％.男性腹泻患者感染诺如病毒GⅡ占26.80％,高于女性的15.32％,差异有统计学意义(x2=13.957,P＜0.01).结论本组腹泻患者粪便标本检测结果以诺如病毒GⅡ型多见,男性高于女性,其次为轮状病毒、星状病毒和腺病毒感染.本组成人腹泻病例病程短,预后良好.
목적 료해성인산발성복사병독감염정황,위림상방치제공의거.방법 수집상해시제오인민의원장도문진2012년5월지2013년4월복사환자분편표본708빈,송상해시민행구질병예방공제중심채용반전록(RT)-PCR진행병독검측.통계학처리채용Pearson잡방검험화Fisher학절개솔검험.결과 708빈분편표본중,검출낙여병독G Ⅰ형7빈,점0.99％;낙여병독GⅡ형150빈,점21.19％;륜상병독21빈,점2.97％;성상병독3빈,점0.42％;선병독4빈,점0.56％.남성복사환자감염낙여병독GⅡ점26.80％,고우녀성적15.32％,차이유통계학의의(x2=13.957,P＜0.01).결론 본조복사환자분편표본검측결과이낙여병독GⅡ형다견,남성고우녀성,기차위륜상병독、성상병독화선병독감염.본조성인복사병례병정단,예후량호.
Objective To explore the viral pathogens of adult sporadic diarrhea,and to provide a theoretical basis for the clinical prevention and treatment.Methods A total of 708 stool samples were collected from diarrheal patients in Enteric Diseases Clinic of Fifth People's Hospital of Shanghai from May 2012 to April 2013.Reverse transcription-polymerase chain reaction (RT-PCR) assay was used for detection of viruses in Minhang District Centers for Disease Control and Prevention in Shanghai.Pearson chi-square test and Fisher exact test were used for statistical analysis.Results Norovirus G Ⅰ was present in 0.99％ (7/708) of cases; Norovirus G Ⅱ was present in 21.19％ (150/708) of cases; Rotavirus was present in 2.97％ (21/708) of cases; Astrovirus was present in 0.42％ (3/708) of cases; Adenovirus was present in 0.56％ (4/708) of cases.Incidence of Norovirus GⅡ was significantly higher in males (26.80％) than in females (15.32％,x2 =13.957,P＜0.01).Conclusions Norovirus G Ⅱ is common etiologic agent of adult sporadic diarrhea,with incidence rate higher in males than in females.Other less common viral pathogens include Rotavirus,Astrovirus and Adenovirus,which are all with short disease duration and good prognosis.