中华创伤杂志
中華創傷雜誌
중화창상잡지
Chinese Journal of Traumatology
2012年
9期
818-822
,共5页
茅尧生%曹淼英%吕铁%李智鑫%周鑫
茅堯生%曹淼英%呂鐵%李智鑫%週鑫
모요생%조묘영%려철%리지흠%주흠
腹部损伤%脓毒症%可溶性髓系细胞触发受体-1
腹部損傷%膿毒癥%可溶性髓繫細胞觸髮受體-1
복부손상%농독증%가용성수계세포촉발수체-1
Abdominal injuries%Sepsis%Soluble triggering receptors expressed on myeloid cells-1
目的 探讨腹部创伤患者腹腔引流液中可溶性髓系细胞触发受体-1(soluble triggering receptors expressed on myeloid cells -1,sTREM -1)的表达及其对创伤后脓毒症的预测价值.方法 将收治的80例腹部创伤患者作为创伤组,30例胃大部切除术后患者作为对照组,分别检测两组患者入院后0,24,48,72 h腹腔引流液sTREM -1、血清sTREM -1、前降钙素( procalcitonin,PCT)和C反应蛋白(C- reactive protein,CRP)的水平,评价上述指标对创伤后脓毒症的早期预测价值. 结果 创伤组患者引流液sTREM -1、血清sTREM -1、PCT和CRP的浓度明显高于对照组(P＜0.05).腹腔引流液sTREM -1预测创伤后脓毒症的受试者工作特征(receiver operating characteristic,ROC)曲线下面积为0.84,敏感性为77％,特异性为83％,优于血清sTREM -1、PCT及CRP. 结论 腹腔引流液sTREM -1可较准确预测腹部创伤并发脓毒症.
目的 探討腹部創傷患者腹腔引流液中可溶性髓繫細胞觸髮受體-1(soluble triggering receptors expressed on myeloid cells -1,sTREM -1)的錶達及其對創傷後膿毒癥的預測價值.方法 將收治的80例腹部創傷患者作為創傷組,30例胃大部切除術後患者作為對照組,分彆檢測兩組患者入院後0,24,48,72 h腹腔引流液sTREM -1、血清sTREM -1、前降鈣素( procalcitonin,PCT)和C反應蛋白(C- reactive protein,CRP)的水平,評價上述指標對創傷後膿毒癥的早期預測價值. 結果 創傷組患者引流液sTREM -1、血清sTREM -1、PCT和CRP的濃度明顯高于對照組(P＜0.05).腹腔引流液sTREM -1預測創傷後膿毒癥的受試者工作特徵(receiver operating characteristic,ROC)麯線下麵積為0.84,敏感性為77％,特異性為83％,優于血清sTREM -1、PCT及CRP. 結論 腹腔引流液sTREM -1可較準確預測腹部創傷併髮膿毒癥.
목적 탐토복부창상환자복강인류액중가용성수계세포촉발수체-1(soluble triggering receptors expressed on myeloid cells -1,sTREM -1)적표체급기대창상후농독증적예측개치.방법 장수치적80례복부창상환자작위창상조,30례위대부절제술후환자작위대조조,분별검측량조환자입원후0,24,48,72 h복강인류액sTREM -1、혈청sTREM -1、전강개소( procalcitonin,PCT)화C반응단백(C- reactive protein,CRP)적수평,평개상술지표대창상후농독증적조기예측개치. 결과 창상조환자인류액sTREM -1、혈청sTREM -1、PCT화CRP적농도명현고우대조조(P＜0.05).복강인류액sTREM -1예측창상후농독증적수시자공작특정(receiver operating characteristic,ROC)곡선하면적위0.84,민감성위77％,특이성위83％,우우혈청sTREM -1、PCT급CRP. 결론 복강인류액sTREM -1가교준학예측복부창상병발농독증.
Objective To investigate the expression of soluble triggering receptors expressed on myeloid cells-1 ( sTREM-1 ) in intraperitoneal drainage fluid of patients with abdorminal trauma and its predictive value for post-traumatic sepsis. Methods A total of 80 abdominal trauma patients were served as the trauma group and 25 patients treated with subtotal gastrectomy as the control group.Intraperitoneal drainage fluid sTREM-1,serum sTREM-1,procalcitonin (PCT) and C-reactive protein (CRP)at 0,24,48,72 hours after admission were determined in two groups for assessing their value in early prediction of post-traumatic sepsis. Results The levels of drainage fluid sTREM-1,serum sTREM-1,PCT and CRP in the trauma group were significantly higher than those in the control group (P ＜ 0.05 ).Drainage fluid sTREM-1 showed the area under the receiver operating characteristic (ROC) curve,sensitivity and specificity for 0.84,77％,and 83％ in the prediction of post-traumatic sepsis,which was superior to the serum sTREM-1,PCT and CRP. Conclusion Intraperitoneal drainage fluid sTREM-1 has high accuracy in predicting the sepsis in abdominal trauma patients.
