CAJ | 학술논문

目的探讨胎儿大脑皮层发育异常的产前超声表现特征.方法回顾性分析我院2012年8月至2014年1月间同时接受超声及MRI检查的胎儿325例.结果 325例胎儿中诊断为大脑皮层发育异常14例(4％),其中超声提示诊断10例,包括灰质异位3例,小头畸形6例,半侧巨脑症1例;超声漏诊4例,分别为脑裂畸形2例,结节性硬化1例,颞叶缺失1例.结论大脑皮层发育异常产前影像表现具有特征性,超声联合MRI对该类疾病产前诊断具有重要作用.
목적 탐토태인대뇌피층발육이상적산전초성표현특정.방법 회고성분석아원2012년8월지2014년1월간동시접수초성급MRI검사적태인325례.결과 325례태인중진단위대뇌피층발육이상14례(4％),기중초성제시진단10례,포괄회질이위3례,소두기형6례,반측거뇌증1례;초성루진4례,분별위뇌렬기형2례,결절성경화1례,섭협결실1례.결론 대뇌피층발육이상산전영상표현구유특정성,초성연합MRI대해류질병산전진단구유중요작용.
Objective To explore sonographic manifestation of fetal malformations of cortical development.Methods From August 2012 to January 2014 three hundred and twenty-five pregnancy women referred to our institution for fetal brain MRI,which were diagnosed or suspected of central nervous system abnormalities by prenatal ultrasound examination.Results In 325 of cases,14 cases (4％) were diagnosed of malformations of cortical development.Ten eases were indicated by prenatal ultrasound,including three cases of heterotopic gray matter,six cases of microcephaly and one case of hemimegalencephaly; four cases were missed by prenatal ultrasound,including two cases of schizencephaly,one case of tuberous sclerosis,and one case of hypoplasia.Conclusions Cortical malformations can be diagnosed by prenatal ultrasonography based on typical imaging characteristics.Prenatal ultrasound combined with MRI is a powerful tool in diagnosing fetal malformations of cortical development.