中华耳鼻咽喉头颈外科杂志
中華耳鼻嚥喉頭頸外科雜誌
중화이비인후두경외과잡지
CHINESE JOURNAL OF OTORHINOLARYNGOLOGY HEAD AND NECK SURGERY
2013年
2期
135-138
,共4页
韩琳%静媛媛%余力生%夏瑞明
韓琳%靜媛媛%餘力生%夏瑞明
한림%정원원%여력생%하서명
梅尼埃病%内淋巴囊%乳突
梅尼埃病%內淋巴囊%乳突
매니애병%내림파낭%유돌
Meniere disease%Endolymphatic sac%Mastoid
目的 通过观察梅尼埃病(Ménière's disease,MD)患者乳突气房发育情况,并与对照组进行比较,探讨MD的病理解剖学基础及可能的发病因素.方法 以行内淋巴囊减压术治疗的100例MD患者(113耳)作为研究对象,选取同期无耳科疾患的100例成年人(100耳)作为对照组.每个研究对象均行颞骨CT扫描,根据影像学资料(MD组同时参考术中所见)将其乳突气房分为气化型、板障型及硬化型.统计两组乳突发育不同类型所占比例,并进行统计学分析.结果 MD组板障型乳突占51.4％(57/113),明显高于对照组的18.0％(18/100),差异具有统计学意义(x2=24.476,P ＜0.001)；MD组气化型乳突占43.4％(49/113),明显低于对照组的77.0％(77/100),差异具有统计学意义(x2=24.843,P＜0.001)；MD组硬化型乳突占6.2％(7/113),对照组硬化型乳突占5.0％(5/100),二者差异无统计学意义(x2=0.142,P＞0.05).结论 MD组患者乳突发育不良,板障型乳突所占比例较对照组明显增加,这可能是MD的病理解剖基础之一,长期的通气引流障碍及其所导致的反复炎性反应发作等因素可能在MD的发生、发展及转归中起重要作用.
目的 通過觀察梅尼埃病(Ménière's disease,MD)患者乳突氣房髮育情況,併與對照組進行比較,探討MD的病理解剖學基礎及可能的髮病因素.方法 以行內淋巴囊減壓術治療的100例MD患者(113耳)作為研究對象,選取同期無耳科疾患的100例成年人(100耳)作為對照組.每箇研究對象均行顳骨CT掃描,根據影像學資料(MD組同時參攷術中所見)將其乳突氣房分為氣化型、闆障型及硬化型.統計兩組乳突髮育不同類型所佔比例,併進行統計學分析.結果 MD組闆障型乳突佔51.4％(57/113),明顯高于對照組的18.0％(18/100),差異具有統計學意義(x2=24.476,P ＜0.001)；MD組氣化型乳突佔43.4％(49/113),明顯低于對照組的77.0％(77/100),差異具有統計學意義(x2=24.843,P＜0.001)；MD組硬化型乳突佔6.2％(7/113),對照組硬化型乳突佔5.0％(5/100),二者差異無統計學意義(x2=0.142,P＞0.05).結論 MD組患者乳突髮育不良,闆障型乳突所佔比例較對照組明顯增加,這可能是MD的病理解剖基礎之一,長期的通氣引流障礙及其所導緻的反複炎性反應髮作等因素可能在MD的髮生、髮展及轉歸中起重要作用.
목적 통과관찰매니애병(Ménière's disease,MD)환자유돌기방발육정황,병여대조조진행비교,탐토MD적병리해부학기출급가능적발병인소.방법 이행내림파낭감압술치료적100례MD환자(113이)작위연구대상,선취동기무이과질환적100례성년인(100이)작위대조조.매개연구대상균행섭골CT소묘,근거영상학자료(MD조동시삼고술중소견)장기유돌기방분위기화형、판장형급경화형.통계량조유돌발육불동류형소점비례,병진행통계학분석.결과 MD조판장형유돌점51.4％(57/113),명현고우대조조적18.0％(18/100),차이구유통계학의의(x2=24.476,P ＜0.001)；MD조기화형유돌점43.4％(49/113),명현저우대조조적77.0％(77/100),차이구유통계학의의(x2=24.843,P＜0.001)；MD조경화형유돌점6.2％(7/113),대조조경화형유돌점5.0％(5/100),이자차이무통계학의의(x2=0.142,P＞0.05).결론 MD조환자유돌발육불량,판장형유돌소점비례교대조조명현증가,저가능시MD적병리해부기출지일,장기적통기인류장애급기소도치적반복염성반응발작등인소가능재MD적발생、발전급전귀중기중요작용.
Objective To investigate the fundamental pathological anatomy and possible pathogentic factors of Ménière's disease(MD),we compared the types of mastoid air cells between the MD group and the control group.Methods The MD group had 113 ears and the control group had 100 ears.Temoral bone CT scanning was performed in all the subjects.The types of mastoid air cells were determined by surgical findings and imaging data.All the mastoid air cells were divided into diploetic type,gasified type and sclerosis type.Analysis of the proportion of different types and the statistical analysis were performed between the two groups.Results 51.4％(57/113)in the MD group and 18.0％(18/100)in the control group were diploetic type mastoid,the difference was significant(x2 =24.476,P ＜ 0.001).The gasified type was 43.4％(49/113)in the MD group and 77.0％(77/100)in the control group,the difference was significant(x2 =24.843,P ＜ 0.001).The sclerosis type was 6.2％ in the MD group and 5.0％(5/100)in the control group,and there was no statistical significance(x2 =0.142,P ＞ 0.05).Conclusions The mastoid air cells are dysplasia in MD patients,and it may be one of the fundamental pathological anatomy.The long-term ventilation and drainage disorder and recurrent inflammation attack may play an important role in occurrence,development and prognosis of MD.
