CAJ | 학술논문

目的分析不同年龄阶段突发性感音神经性聋(sudden sensorineural heanngloss,简称突发性聋)患者的临床资料,了解疾病在各个年龄段的临床特征及疗效预后.方法选取2008年6月至2010年5月住院治疗的突发性聋患者318例,按照年龄阶段分为三组:1组(青少年组,≤18岁)32例,2组(成年组,19 ～59岁)235例,3组(老年组,≥60岁)51例.对比分析不同年龄组突发性聋患者的临床表现、诱发因素及疗效预后情况.结果青少年组28.1％(9/32)的患者有明确的病毒感染史,成年组中有18.7％ (44/235)的患者在发病前有明显的情绪波动或劳累史.三组中伴发耳闷症状的患者分别占3.1％(1/32)、41.3％(97/235)和29.4％(15/51).三组中分别有62.5％ (20/32)、40.0％ (94/235)和33.3％(17/51)的患者为极重度听力损失,其中青少年组患者表现为极重度听力损失的比例高于其他两组(P值均＜0.05).经过系统的内科治疗,三组听力改善比例分别为:31.2％(10/32)、77.4％(182/235)和64.7％(33/51),其中青少年组患者疗效较差.结论不同年龄段突发性聋具有各自不同的临床特征和预后,其中青少年患者听力损失重、预后差.
목적 분석불동년령계단돌발성감음신경성롱(sudden sensorineural heanngloss,간칭돌발성롱)환자적림상자료,료해질병재각개년령단적림상특정급료효예후.방법 선취2008년6월지2010년5월주원치료적돌발성롱환자318례,안조년령계단분위삼조:1조(청소년조,≤18세)32례,2조(성년조,19 ～59세)235례,3조(노년조,≥60세)51례.대비분석불동년령조돌발성롱환자적림상표현、유발인소급료효예후정황.결과 청소년조28.1％(9/32)적환자유명학적병독감염사,성년조중유18.7％ (44/235)적환자재발병전유명현적정서파동혹로루사.삼조중반발이민증상적환자분별점3.1％(1/32)、41.3％(97/235)화29.4％(15/51).삼조중분별유62.5％ (20/32)、40.0％ (94/235)화33.3％(17/51)적환자위겁중도은력손실,기중청소년조환자표현위겁중도은력손실적비례고우기타량조(P치균＜0.05).경과계통적내과치료,삼조은력개선비례분별위:31.2％(10/32)、77.4％(182/235)화64.7％(33/51),기중청소년조환자료효교차.결론 불동년령단돌발성롱구유각자불동적림상특정화예후,기중청소년환자은력손실중、예후차.
Objective To investigate the clinical materials of sudden sensorineural hearing loss (SSNHL) in different ages of patients,and explore their clinical characteristics and prognosis.Methods A retrospective review was conducted by the clinical symptoms,predisposing factors and prognosis in SSNHL patients with different ages in the past two years (from 2008 to 2010).All patients were divided into three groups according to age,including Group 1 (0-18 years old),Group 2(19-59 years old),and Group 3(over 60 years old).Results Part of patients (28.1％) had a clear history of virus infection in Group 1.Some patients (18.7％) had obvious history of emotional fluctuations or fatigue before the onset of SSNHL.Three groups of patients with "aural fullness" symptom accounted for 3.1％,41.3％ and 29.4％ respectively.The proportions of patients with profound hearing loss in three groups were 62.5％,40.0％ and 33.3％ respectively.Most patients improved hearing level during systemic internal medicine treatment.However,many patients (68.8％) in Group 1 showed poor therapeutic effect.Conclusions SSNHL in different age stages has different clinical features.We can improve the personalized treatment program to this disease through the classification and grading treatment.