中华耳鼻咽喉头颈外科杂志
中華耳鼻嚥喉頭頸外科雜誌
중화이비인후두경외과잡지
CHINESE JOURNAL OF OTORHINOLARYNGOLOGY HEAD AND NECK SURGERY
2013年
5期
389-393
,共5页
张青%胡娟%许信达%陈彦飞%张滟%韦俊荣%张全安%许珉%加我君孝
張青%鬍娟%許信達%陳彥飛%張滟%韋俊榮%張全安%許珉%加我君孝
장청%호연%허신체%진언비%장염%위준영%장전안%허민%가아군효
听觉丧失,突发性%前庭,迷路%耳石膜%前庭诱发肌源性电位
聽覺喪失,突髮性%前庭,迷路%耳石膜%前庭誘髮肌源性電位
은각상실,돌발성%전정,미로%이석막%전정유발기원성전위
Hearing loss,sudden%Vestibule,labyrinth%Otolithic membrane%Vestibular evoked myogenic potentials
目的 观察突发性聋(简称突聋)患者耳蜗受损时前庭耳石器传导通路受影响的范围、程度以及客观评价方法.方法 选择2011年5月至2012年5月住院接受治疗的单侧突聋患者40例,分别进行气导短纯音诱发的眼肌前庭诱发肌源性电位(ocular vestibular evoked myogenic potential,oVEMP)和颈肌前庭诱发肌源性电位(cervical vestibular evoked myogenic potential,cVEMP)检测,计算两种反射的引出率；分别以突聋对侧相对健康耳和30名健康人(60耳)为对照,分析前庭上成分(椭圆囊/前庭上神经)和前庭下成分(球囊/前庭下神经)功能受损状况.结果 突聋组患耳oVEMP引出率为40.0％ (16/40),cVEMP引出率为62.5％ (25/40)；突聋组对侧健耳oVEMP引出率为57.5％(23/40),cVEMP引出率为75.0％ (30/40)；对照组oVEMP引出率为71.7％(43/60),cVEMP引出率为81.7％ (49/60).组间对比显示突聋组患耳与对侧健耳oVEMP和cVEMP引出率差异无统计学意义(x2=2.452,P=0.117;x2 =0.251,P=0.617),突聋组患耳与对照组比较,oVEMP和cVEMP引出率差异均具有统计学意义(x2 =9.949,P=0.002；x2=4.582,P=0.032);突聋组患耳、对侧健耳、对照组正常耳组间比较,oVEMP和cVEMP的阈值、N1潜伏期、P1潜伏期、波间期、振幅等各参数差异均无统计学意义(P值均＞0.05).结论 突聋患者在耳蜗受损的同时可以伴有前庭耳石器传导通路功能受损,这种功能受损的状况可以通过oVEMP和cVEMP检测进行客观评估.
目的 觀察突髮性聾(簡稱突聾)患者耳蝸受損時前庭耳石器傳導通路受影響的範圍、程度以及客觀評價方法.方法 選擇2011年5月至2012年5月住院接受治療的單側突聾患者40例,分彆進行氣導短純音誘髮的眼肌前庭誘髮肌源性電位(ocular vestibular evoked myogenic potential,oVEMP)和頸肌前庭誘髮肌源性電位(cervical vestibular evoked myogenic potential,cVEMP)檢測,計算兩種反射的引齣率；分彆以突聾對側相對健康耳和30名健康人(60耳)為對照,分析前庭上成分(橢圓囊/前庭上神經)和前庭下成分(毬囊/前庭下神經)功能受損狀況.結果 突聾組患耳oVEMP引齣率為40.0％ (16/40),cVEMP引齣率為62.5％ (25/40)；突聾組對側健耳oVEMP引齣率為57.5％(23/40),cVEMP引齣率為75.0％ (30/40)；對照組oVEMP引齣率為71.7％(43/60),cVEMP引齣率為81.7％ (49/60).組間對比顯示突聾組患耳與對側健耳oVEMP和cVEMP引齣率差異無統計學意義(x2=2.452,P=0.117;x2 =0.251,P=0.617),突聾組患耳與對照組比較,oVEMP和cVEMP引齣率差異均具有統計學意義(x2 =9.949,P=0.002；x2=4.582,P=0.032);突聾組患耳、對側健耳、對照組正常耳組間比較,oVEMP和cVEMP的閾值、N1潛伏期、P1潛伏期、波間期、振幅等各參數差異均無統計學意義(P值均＞0.05).結論 突聾患者在耳蝸受損的同時可以伴有前庭耳石器傳導通路功能受損,這種功能受損的狀況可以通過oVEMP和cVEMP檢測進行客觀評估.
목적 관찰돌발성롱(간칭돌롱)환자이와수손시전정이석기전도통로수영향적범위、정도이급객관평개방법.방법 선택2011년5월지2012년5월주원접수치료적단측돌롱환자40례,분별진행기도단순음유발적안기전정유발기원성전위(ocular vestibular evoked myogenic potential,oVEMP)화경기전정유발기원성전위(cervical vestibular evoked myogenic potential,cVEMP)검측,계산량충반사적인출솔；분별이돌롱대측상대건강이화30명건강인(60이)위대조,분석전정상성분(타원낭/전정상신경)화전정하성분(구낭/전정하신경)공능수손상황.결과 돌롱조환이oVEMP인출솔위40.0％ (16/40),cVEMP인출솔위62.5％ (25/40)；돌롱조대측건이oVEMP인출솔위57.5％(23/40),cVEMP인출솔위75.0％ (30/40)；대조조oVEMP인출솔위71.7％(43/60),cVEMP인출솔위81.7％ (49/60).조간대비현시돌롱조환이여대측건이oVEMP화cVEMP인출솔차이무통계학의의(x2=2.452,P=0.117;x2 =0.251,P=0.617),돌롱조환이여대조조비교,oVEMP화cVEMP인출솔차이균구유통계학의의(x2 =9.949,P=0.002；x2=4.582,P=0.032);돌롱조환이、대측건이、대조조정상이조간비교,oVEMP화cVEMP적역치、N1잠복기、P1잠복기、파간기、진폭등각삼수차이균무통계학의의(P치균＞0.05).결론 돌롱환자재이와수손적동시가이반유전정이석기전도통로공능수손,저충공능수손적상황가이통과oVEMP화cVEMP검측진행객관평고.
Objective To observe the function of the otolithic end organs and their input pathways in sudden sensorineural hearing loss (SSHL) patients.Methods Forty cases of unilateral SSHL were enrolled as the observing group from May,2011 to May,2012.Thirty age-and gender-matched normal subjects were recruited as the control group.Both patients and normal subjects underwent conventional airconducted ocular vestibular evoked myogenic potential (oVEMP) and cervical vestibular evoked myogenic potential (cVEMP) in bilateral ears.The results were compared between the affected ears,the contralateral ears and the normal controls.Results Overall,oVEMP was elicited in 16 affected ears (40.0％),23 contralateral ears (57.5％) and 43 normal ears (71.7％).cVEMP could be elicited in 25 affected ears (62.5％),30 contralateral ears (75.0％) and 49 normal ears (81.7％) respectively.Significant statistical significance could be found in the oVEMP response rate between the affected ears and the normal ears (x2 =9.949,P =0.002) and in the cVEMP response rate between the affected ears and the normal ears (x2 =4.582,P =0.032).Significant statistical difference could not be found in all oVEMP and cVEMP parameters (threshold,N1 latency,P1 latcncy,latency interval and amplitude) among groups (P ＞ 0.05).Conclusions The otolithic vestibular end organs and their input pathways could be damaged in SSHL patients.Such damages could be monitored objectively by cVEMP and oVEMP examinations.
