中华耳鼻咽喉头颈外科杂志
中華耳鼻嚥喉頭頸外科雜誌
중화이비인후두경외과잡지
CHINESE JOURNAL OF OTORHINOLARYNGOLOGY HEAD AND NECK SURGERY
2014年
2期
121-124
,共4页
内窥镜检查%耳鼻喉外科手术%脑脊液鼻漏%中枢神经系统感染
內窺鏡檢查%耳鼻喉外科手術%腦脊液鼻漏%中樞神經繫統感染
내규경검사%이비후외과수술%뇌척액비루%중추신경계통감염
Endoscopy%Otorhinolaryngologic surgical procedures%Cerebrospinal fluid rhinorrhea%Central nervous system infections
目的 分析经鼻内镜下脑脊液鼻漏修补术后颅内感染的因素.方法 对173例经鼻内镜下脑脊液鼻漏修补术患者资料进行回顾性分析,采用SPSS 17.0软件对可能造成颅内感染的因素进行多因素Logistic逐步回归分析.结果 173例患者中,术后感染17例(9.83％);脑脊液鼻漏修补失败(x2 =6.89,P=O.001)、颅底缺损直径＞1 cm(x2 =9.98,P =0.001)、既往有颅内感染病史(x2 =11.08,P=o.oo1)是经鼻内镜下脑脊液鼻漏修补术后颅内感染的影响因素(P值均＜0.05),而性别、年龄、漏口位置、发病原因、术前是否应用抗菌药物和术后应用抗菌药物是否＞7d、手术是否使用人工材料对术后颅内并发感染影响不明显(P值均＞0.05).结论 经鼻内镜下脑脊液鼻漏修补术后颅内感染受诸如脑脊液鼻漏修补失败、颅底缺损直径大小、既往颅内感染史等多种因素的影响.
目的 分析經鼻內鏡下腦脊液鼻漏脩補術後顱內感染的因素.方法 對173例經鼻內鏡下腦脊液鼻漏脩補術患者資料進行迴顧性分析,採用SPSS 17.0軟件對可能造成顱內感染的因素進行多因素Logistic逐步迴歸分析.結果 173例患者中,術後感染17例(9.83％);腦脊液鼻漏脩補失敗(x2 =6.89,P=O.001)、顱底缺損直徑＞1 cm(x2 =9.98,P =0.001)、既往有顱內感染病史(x2 =11.08,P=o.oo1)是經鼻內鏡下腦脊液鼻漏脩補術後顱內感染的影響因素(P值均＜0.05),而性彆、年齡、漏口位置、髮病原因、術前是否應用抗菌藥物和術後應用抗菌藥物是否＞7d、手術是否使用人工材料對術後顱內併髮感染影響不明顯(P值均＞0.05).結論 經鼻內鏡下腦脊液鼻漏脩補術後顱內感染受諸如腦脊液鼻漏脩補失敗、顱底缺損直徑大小、既往顱內感染史等多種因素的影響.
목적 분석경비내경하뇌척액비루수보술후로내감염적인소.방법 대173례경비내경하뇌척액비루수보술환자자료진행회고성분석,채용SPSS 17.0연건대가능조성로내감염적인소진행다인소Logistic축보회귀분석.결과 173례환자중,술후감염17례(9.83％);뇌척액비루수보실패(x2 =6.89,P=O.001)、로저결손직경＞1 cm(x2 =9.98,P =0.001)、기왕유로내감염병사(x2 =11.08,P=o.oo1)시경비내경하뇌척액비루수보술후로내감염적영향인소(P치균＜0.05),이성별、년령、루구위치、발병원인、술전시부응용항균약물화술후응용항균약물시부＞7d、수술시부사용인공재료대술후로내병발감염영향불명현(P치균＞0.05).결론 경비내경하뇌척액비루수보술후로내감염수제여뇌척액비루수보실패、로저결손직경대소、기왕로내감염사등다충인소적영향.
Objective To analyze the factors of intracranial infection after transnasal endoscopic repair of cerebrospinal fluid rhinorrhea.Methods One hundred and seventy-three patients who accepted transnasal endoscopic repair of cerebrospinal fluid rhinorrhea were retrospectively analyzed.The intracranial infection factors was analyzed by Logistic regression analysis with SPSS 17.0 software.Results Postoperative infection was found in 17 cases among 173 patients,the infection rate was 9.83％.The unsuccessful transnasal endoscopic repair of cerebrospinal fluid rhinorrhea (x2 =6.89,P =0.001),the defective diameter of skull base (x2 =9.98,P =0.001) and medical history of intracranial infection (x2 =11.08,P =0.001) were infection factors after transnasal endoscopic repair of cerebrospinal fluid rhinorrhea (all P ＜ 0.05),while sex,age,the site of defection,the aetiological agent,longer application of antibiotics before or after operation and the use of artificial material had no obvious effect (all P ＞ 0.05).Conclusion Intracranial infection after transnasal endoscopic repair of cerebrospinal fluid rhinorrhea is affected by many factors,such as the unsuccessful transnasal endoscopic repair of cerebrospinal fluid rhinorrhea,the defective diameter of skull base and medical history of intracranial infection.
