CAJ | 학술논문

目的探讨窄带成像技术(narrow band imaging,NBI)在鼻咽癌早期诊断中的应用.方法对2011年10月至2012年3月疑似鼻咽部病变患者55例(包括9例鼻咽癌治疗后患者)分别行白光及NBI模式下内镜检查,记录图片资料并行病理活检,以病理诊断为金标准评估两种模式下诊断的符合率.应用SPSSI3.0软件行x2检验. 结果本组首诊鼻咽癌患者37例,Ⅰ期5例,Ⅱ期7例,Ⅲ期12例,Ⅳ期13例;鼻咽癌治疗后复发6例,均为Ⅰ期;黏膜慢性炎12例.NBI模式的诊断符合率为93.0％ (40/43),白光模式诊断符合率为41.9％(18/43).NBI模式在Ⅰ期、Ⅱ期鼻咽癌病例的诊断符合率分别为100.0％ (5/5)和85.7％ (6/7),显著高于白光模式的0和14.3％ (1/7),分别差异均有统计学意义(x2=10.000,P=O.008;x2 =7.143,P=0.029).结论窄带成像技术在鼻咽癌早期诊断乃至治疗后复查方面,较普通内镜具有更高的应用价值,有望成为鼻咽癌早期确诊的重要手段之一.
목적 탐토착대성상기술(narrow band imaging,NBI)재비인암조기진단중적응용.방법 대2011년10월지2012년3월의사비인부병변환자55례(포괄9례비인암치료후환자)분별행백광급NBI모식하내경검사,기록도편자료병행병리활검,이병리진단위금표준평고량충모식하진단적부합솔.응용SPSSI3.0연건행x2검험. 결과 본조수진비인암환자37례,Ⅰ기5례,Ⅱ기7례,Ⅲ기12례,Ⅳ기13례;비인암치료후복발6례,균위Ⅰ기;점막만성염12례.NBI모식적진단부합솔위93.0％ (40/43),백광모식진단부합솔위41.9％(18/43).NBI모식재Ⅰ기、Ⅱ기비인암병례적진단부합솔분별위100.0％ (5/5)화85.7％ (6/7),현저고우백광모식적0화14.3％ (1/7),분별차이균유통계학의의(x2=10.000,P=O.008;x2 =7.143,P=0.029).결론 착대성상기술재비인암조기진단내지치료후복사방면,교보통내경구유경고적응용개치,유망성위비인암조기학진적중요수단지일.
Objective To investigate the use of NBI (narrow band imaging) in early the diagnosis of nasopharyngeal carcinoma.Methods A total of 55 cases with nasopharyngeal lesions (including 9 cases of nasopharyngeal carcinoma after treatment) were examined and diagnosed by white and NBI endoscopy between October 2011 and March 2012,and their diagnosis efficacies were evaluated based on pathological diagnosis as a gold standard.Chi-square test was used to analyze data.Results Of 55 cases,12 cases were pathologically diagnosed as chronic mucosa inflammation and 43 as nasopharyngeal carcinoma including 6 recurrent cases,of 43 cases,40(93.0％) were diagnosed by NBI endoscopy and 18 (41.9％) by white endoscopy.Of 12 cases with early nasopharyngeal carcinoma (5 for stage Ⅰ and 7 for stage Ⅱ),5(100.0％) for stage Ⅰ,and 6 (85.7％) for stage Ⅱ were diagnosed by NBI endoscopy but only 1(14.3％) for stage Ⅱ by white endoscopy,with a statistically significant difference (x2 =10.000,P =0.008 ;x2 =7.143,P =0.029).Conclusion NBI endoscopy can be used in early diagnosis of nasopharyngeal carcinoma and check after treatment.