中华耳鼻咽喉头颈外科杂志
中華耳鼻嚥喉頭頸外科雜誌
중화이비인후두경외과잡지
CHINESE JOURNAL OF OTORHINOLARYNGOLOGY HEAD AND NECK SURGERY
2014年
11期
897-901
,共5页
张青%许信达%牛晓蓉%胡娟%陈彦飞%许珉
張青%許信達%牛曉蓉%鬍娟%陳彥飛%許珉
장청%허신체%우효용%호연%진언비%허민
前庭诱发肌源性电位%声刺激%年龄因素
前庭誘髮肌源性電位%聲刺激%年齡因素
전정유발기원성전위%성자격%년령인소
Vestibular evoked myogenic potentials%Acoustic stimulation%Age factors
目的 了解年龄增长对正常人气导声刺激(air conducted sound,ACS)诱发的眼肌前庭诱发肌源性电位(ocular vestibular-evoked myogenic potentia,oVEMP)和颈肌前庭肌源性诱发电位(cervical vestibular-evoked myogenic potential,cVEMP)的影响.方法 选择不同年龄段健康人97名(194耳)作为研究对象,男41名(82耳),女56名(112耳);年龄4～ 83岁,平均(45.7±19.3)岁,分为≤10岁,11 ～30岁,31～50岁,51 ～70岁,＞70岁组共5个年龄段(年龄以周岁计).以气导短纯音为刺激声,分别进行气导声刺激诱发的oVEMP和cVEMP检测,进行各年龄段波形参数计算和年龄组间的对比.采用SPSS 13.0软件进行统计学分析.结果 全组健康人oVEMP和cVEMP总体引出率分别为72.70％和85.05％.随着年龄增长,无论oVEMP还是cVEMP,均表现出引出率下降、阈值增高和振幅减低的特点.＞ 70岁年龄组健康人oVEMP引出率低至15.00％ (3/20),cVEMP引出率低至45.00％ (9/20).结论 随着年龄增长,健康人前庭耳石器反射通路表现出机能下降的趋势.由于气导声刺激诱发的oVEMP和cVEMP在70岁以上年龄组引出率过低,其在高龄人群前庭疾病检测中的适用性还有待于进一步深入探讨.
目的 瞭解年齡增長對正常人氣導聲刺激(air conducted sound,ACS)誘髮的眼肌前庭誘髮肌源性電位(ocular vestibular-evoked myogenic potentia,oVEMP)和頸肌前庭肌源性誘髮電位(cervical vestibular-evoked myogenic potential,cVEMP)的影響.方法 選擇不同年齡段健康人97名(194耳)作為研究對象,男41名(82耳),女56名(112耳);年齡4～ 83歲,平均(45.7±19.3)歲,分為≤10歲,11 ～30歲,31～50歲,51 ～70歲,＞70歲組共5箇年齡段(年齡以週歲計).以氣導短純音為刺激聲,分彆進行氣導聲刺激誘髮的oVEMP和cVEMP檢測,進行各年齡段波形參數計算和年齡組間的對比.採用SPSS 13.0軟件進行統計學分析.結果 全組健康人oVEMP和cVEMP總體引齣率分彆為72.70％和85.05％.隨著年齡增長,無論oVEMP還是cVEMP,均錶現齣引齣率下降、閾值增高和振幅減低的特點.＞ 70歲年齡組健康人oVEMP引齣率低至15.00％ (3/20),cVEMP引齣率低至45.00％ (9/20).結論 隨著年齡增長,健康人前庭耳石器反射通路錶現齣機能下降的趨勢.由于氣導聲刺激誘髮的oVEMP和cVEMP在70歲以上年齡組引齣率過低,其在高齡人群前庭疾病檢測中的適用性還有待于進一步深入探討.
목적 료해년령증장대정상인기도성자격(air conducted sound,ACS)유발적안기전정유발기원성전위(ocular vestibular-evoked myogenic potentia,oVEMP)화경기전정기원성유발전위(cervical vestibular-evoked myogenic potential,cVEMP)적영향.방법 선택불동년령단건강인97명(194이)작위연구대상,남41명(82이),녀56명(112이);년령4～ 83세,평균(45.7±19.3)세,분위≤10세,11 ～30세,31～50세,51 ～70세,＞70세조공5개년령단(년령이주세계).이기도단순음위자격성,분별진행기도성자격유발적oVEMP화cVEMP검측,진행각년령단파형삼수계산화년령조간적대비.채용SPSS 13.0연건진행통계학분석.결과 전조건강인oVEMP화cVEMP총체인출솔분별위72.70％화85.05％.수착년령증장,무론oVEMP환시cVEMP,균표현출인출솔하강、역치증고화진폭감저적특점.＞ 70세년령조건강인oVEMP인출솔저지15.00％ (3/20),cVEMP인출솔저지45.00％ (9/20).결론 수착년령증장,건강인전정이석기반사통로표현출궤능하강적추세.유우기도성자격유발적oVEMP화cVEMP재70세이상년령조인출솔과저,기재고령인군전정질병검측중적괄용성환유대우진일보심입탐토.
Objective To identify the aging effects on air-conducted sound (ACS) elicited ocular vestibular-evoked myogenic potential (oVEMP) and cervical vestibular-evoked myogenic potential (cVEMP) in normal Chinese population.Methods Nighty-seven normal subjects (194 ears) were recruited for conventional ACS-oVEMP and ACS-cVEMP examinations.The candidates'age were 4-83 years old (Ave.± SD,45.7 ± 19.3),41 male and 56 female,divided into 5 groups according to age.500 Hz short tone burst was employed for examinations.Thresholds were identified and the parameters of the responses to 100dB nHL were calculated and compared among groups.SPSS 13.0 software was used to analyze the date.Results As the age growing,the response rate for oVEMP decreased.It was recorded 100％ in both ≤ 10-year-old and 11-30-year-old groups,84.00％ in the 31-50-year-old group,48.15％ in the 51-70-year-old group and 15.00％ in the ＞70-year-old group; while that for cVEMP were 100％ in both-≤10-year-old group and 11-30-year-old group,82.00％ in the 31-50-year-old group,77.78％ in the 51-70-year-old group and 45.00％ in the ＞ 70-year-old group.The thresholds elevated and the amplitudes decreased in both examinations with the age growing.However,latencies and latency-intervals of both oVEMP and cVEMP examinations displayed minor difference among groups except that nI latency of oVEMP prolonged with age growing.Conclusions With the age growing,the otolithic end organ input pathways degenerate in normal subjects,as shown that ACS elicited oVEMP and cVEMP responsed less with higher threshold and smaller amplitude.The extremely low response rates of both VEMPs in the ＞70-year-old group in this study indicates that VEMPs can only provide limited diagnostic information among very old people in clinical practice.
